d1r Search Results


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  • 94
    Bio-Techne corporation antibodies against drd1
    Protein-drug binding simulations. Seven transmembrane domains of <t>DRD1</t> are shown as multicolor bands. METH or CBD are marked in cyan, while key DRD1 residues are marked in yellow. (A) Docking pose, binding sites, and interactions between DRD1 model and METH. (B) Docking pose, binding sites, and interactions between DRD1 model and CBD. (C) Docking pose, binding sites, and interactions among CBD, METH, and DRD1 model.
    Antibodies Against Drd1, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/antibodies against drd1/product/Bio-Techne corporation
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    antibodies against drd1 - by Bioz Stars, 2024-06
    94/100 stars
      Buy from Supplier

    93
    Addgene inc pcag d1r
    Protein-drug binding simulations. Seven transmembrane domains of <t>DRD1</t> are shown as multicolor bands. METH or CBD are marked in cyan, while key DRD1 residues are marked in yellow. (A) Docking pose, binding sites, and interactions between DRD1 model and METH. (B) Docking pose, binding sites, and interactions between DRD1 model and CBD. (C) Docking pose, binding sites, and interactions among CBD, METH, and DRD1 model.
    Pcag D1r, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pcag d1r/product/Addgene inc
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    pcag d1r - by Bioz Stars, 2024-06
    93/100 stars
      Buy from Supplier

    86
    Millipore d1r
    Key resources table
    D1r, supplied by Millipore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/d1r/product/Millipore
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    d1r - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    86
    Intra-Cellular Therapies Inc d1r
    Key resources table
    D1r, supplied by Intra-Cellular Therapies Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/d1r/product/Intra-Cellular Therapies Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    d1r - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    Image Search Results


    Protein-drug binding simulations. Seven transmembrane domains of DRD1 are shown as multicolor bands. METH or CBD are marked in cyan, while key DRD1 residues are marked in yellow. (A) Docking pose, binding sites, and interactions between DRD1 model and METH. (B) Docking pose, binding sites, and interactions between DRD1 model and CBD. (C) Docking pose, binding sites, and interactions among CBD, METH, and DRD1 model.

    Journal: Frontiers in Pharmacology

    Article Title: Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2

    doi: 10.3389/fphar.2022.972828

    Figure Lengend Snippet: Protein-drug binding simulations. Seven transmembrane domains of DRD1 are shown as multicolor bands. METH or CBD are marked in cyan, while key DRD1 residues are marked in yellow. (A) Docking pose, binding sites, and interactions between DRD1 model and METH. (B) Docking pose, binding sites, and interactions between DRD1 model and CBD. (C) Docking pose, binding sites, and interactions among CBD, METH, and DRD1 model.

    Article Snippet: The membranes were blocked with 5% dry skimmed milk in Tris-buffered saline and incubated overnight at 4°C in blocking solution containing primary antibodies against DRD1 (Bio-Techne, #NB110-60017, 1:800, Minneapolis, MN, United States), pMeCP2 (phospho Ser421) (Abcam, #ab254050, 1:1,000, Cambridge, United Kingdom), caspase-8 (Abcam, #ab25901, 1:1,000, Cambridge, United Kingdom), cleaved caspase-8 (Proteintech, #66093-1-Ig, 1:2,000, IL, United States), caspase-3 (Cell Signaling Technology, #9662, 1:1,000, MA, United States), cleaved caspase-3 (Cell Signaling Technology, #9664, 1:1,000, MA, United States), and β-actin (Proteintech, #66009–1, 1:5,000, IL, United States).

    Techniques: Binding Assay

    Protein levels and colocalization in neurons incubated with CBD and/or METH. (A) Levels of pMeCP2 and apoptosis-related proteins. (B) DRD1 and pMeCP2 levels and their colocalization. (C) Cleaved caspase-8 and cleaved caspase-3 levels and their colocalization. ** p < 0.01 or *** p < 0.001 compared with control group, # p < 0.05 or ### p < 0.001 compared with METH group; Tukey HSD post-hoc comparison after significant ANOVA.

    Journal: Frontiers in Pharmacology

    Article Title: Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2

    doi: 10.3389/fphar.2022.972828

    Figure Lengend Snippet: Protein levels and colocalization in neurons incubated with CBD and/or METH. (A) Levels of pMeCP2 and apoptosis-related proteins. (B) DRD1 and pMeCP2 levels and their colocalization. (C) Cleaved caspase-8 and cleaved caspase-3 levels and their colocalization. ** p < 0.01 or *** p < 0.001 compared with control group, # p < 0.05 or ### p < 0.001 compared with METH group; Tukey HSD post-hoc comparison after significant ANOVA.

    Article Snippet: The membranes were blocked with 5% dry skimmed milk in Tris-buffered saline and incubated overnight at 4°C in blocking solution containing primary antibodies against DRD1 (Bio-Techne, #NB110-60017, 1:800, Minneapolis, MN, United States), pMeCP2 (phospho Ser421) (Abcam, #ab254050, 1:1,000, Cambridge, United Kingdom), caspase-8 (Abcam, #ab25901, 1:1,000, Cambridge, United Kingdom), cleaved caspase-8 (Proteintech, #66093-1-Ig, 1:2,000, IL, United States), caspase-3 (Cell Signaling Technology, #9662, 1:1,000, MA, United States), cleaved caspase-3 (Cell Signaling Technology, #9664, 1:1,000, MA, United States), and β-actin (Proteintech, #66009–1, 1:5,000, IL, United States).

    Techniques: Incubation, Comparison

    Protein levels and colocalization in neurons incubated with SCH23390 and/or METH. (A) Levels of pMeCP2 and apoptosis-related proteins. (B) DRD1 and pMeCP2 levels and their colocalization. (C) Cleaved caspase-8 and cleaved caspase-3 levels and their colocalization. ** p < 0.01 or *** p < 0.001 compared with control group, ## p < 0.01 or ### p < 0.001 compared with METH group, && p < 0.01 or &&& p < 0.001 compared with SCH23390 group; Tukey HSD post-hoc comparison after significant ANOVA.

    Journal: Frontiers in Pharmacology

    Article Title: Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2

    doi: 10.3389/fphar.2022.972828

    Figure Lengend Snippet: Protein levels and colocalization in neurons incubated with SCH23390 and/or METH. (A) Levels of pMeCP2 and apoptosis-related proteins. (B) DRD1 and pMeCP2 levels and their colocalization. (C) Cleaved caspase-8 and cleaved caspase-3 levels and their colocalization. ** p < 0.01 or *** p < 0.001 compared with control group, ## p < 0.01 or ### p < 0.001 compared with METH group, && p < 0.01 or &&& p < 0.001 compared with SCH23390 group; Tukey HSD post-hoc comparison after significant ANOVA.

    Article Snippet: The membranes were blocked with 5% dry skimmed milk in Tris-buffered saline and incubated overnight at 4°C in blocking solution containing primary antibodies against DRD1 (Bio-Techne, #NB110-60017, 1:800, Minneapolis, MN, United States), pMeCP2 (phospho Ser421) (Abcam, #ab254050, 1:1,000, Cambridge, United Kingdom), caspase-8 (Abcam, #ab25901, 1:1,000, Cambridge, United Kingdom), cleaved caspase-8 (Proteintech, #66093-1-Ig, 1:2,000, IL, United States), caspase-3 (Cell Signaling Technology, #9662, 1:1,000, MA, United States), cleaved caspase-3 (Cell Signaling Technology, #9664, 1:1,000, MA, United States), and β-actin (Proteintech, #66009–1, 1:5,000, IL, United States).

    Techniques: Incubation, Comparison

    Protein levels and colocalization in neurons incubated with CBD and/or SKF81297. (A) Levels of pMeCP2 and apoptosis-related proteins. (B) DRD1 and pMeCP2 levels and their colocalization. (C) Cleaved caspase-8 and cleaved caspase-3 levels and their colocalization. ** p < 0.01 or *** p < 0.001 compared with control group, ## p < 0.01 or ### p < 0.001 compared with METH group; Tukey HSD post-hoc comparison after significant ANOVA.

    Journal: Frontiers in Pharmacology

    Article Title: Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2

    doi: 10.3389/fphar.2022.972828

    Figure Lengend Snippet: Protein levels and colocalization in neurons incubated with CBD and/or SKF81297. (A) Levels of pMeCP2 and apoptosis-related proteins. (B) DRD1 and pMeCP2 levels and their colocalization. (C) Cleaved caspase-8 and cleaved caspase-3 levels and their colocalization. ** p < 0.01 or *** p < 0.001 compared with control group, ## p < 0.01 or ### p < 0.001 compared with METH group; Tukey HSD post-hoc comparison after significant ANOVA.

    Article Snippet: The membranes were blocked with 5% dry skimmed milk in Tris-buffered saline and incubated overnight at 4°C in blocking solution containing primary antibodies against DRD1 (Bio-Techne, #NB110-60017, 1:800, Minneapolis, MN, United States), pMeCP2 (phospho Ser421) (Abcam, #ab254050, 1:1,000, Cambridge, United Kingdom), caspase-8 (Abcam, #ab25901, 1:1,000, Cambridge, United Kingdom), cleaved caspase-8 (Proteintech, #66093-1-Ig, 1:2,000, IL, United States), caspase-3 (Cell Signaling Technology, #9662, 1:1,000, MA, United States), cleaved caspase-3 (Cell Signaling Technology, #9664, 1:1,000, MA, United States), and β-actin (Proteintech, #66009–1, 1:5,000, IL, United States).

    Techniques: Incubation, Comparison

    Protein, intracellular Ca 2+ , and apoptosis levels in prefrontal cortex of rats repeatedly exposed to CBD and/or METH. (A) Levels of DRD1, pMeCP2, and apoptosis-related proteins in prefrontal cortex. (B) Intracellular Ca 2+ level in prefrontal cortex. (C) Apoptosis level in prefrontal cortex. *** p < 0.001 compared with control group, ### p < 0.001 compared with METH group; Tukey HSD post-hoc comparison after significant ANOVA.

    Journal: Frontiers in Pharmacology

    Article Title: Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2

    doi: 10.3389/fphar.2022.972828

    Figure Lengend Snippet: Protein, intracellular Ca 2+ , and apoptosis levels in prefrontal cortex of rats repeatedly exposed to CBD and/or METH. (A) Levels of DRD1, pMeCP2, and apoptosis-related proteins in prefrontal cortex. (B) Intracellular Ca 2+ level in prefrontal cortex. (C) Apoptosis level in prefrontal cortex. *** p < 0.001 compared with control group, ### p < 0.001 compared with METH group; Tukey HSD post-hoc comparison after significant ANOVA.

    Article Snippet: The membranes were blocked with 5% dry skimmed milk in Tris-buffered saline and incubated overnight at 4°C in blocking solution containing primary antibodies against DRD1 (Bio-Techne, #NB110-60017, 1:800, Minneapolis, MN, United States), pMeCP2 (phospho Ser421) (Abcam, #ab254050, 1:1,000, Cambridge, United Kingdom), caspase-8 (Abcam, #ab25901, 1:1,000, Cambridge, United Kingdom), cleaved caspase-8 (Proteintech, #66093-1-Ig, 1:2,000, IL, United States), caspase-3 (Cell Signaling Technology, #9662, 1:1,000, MA, United States), cleaved caspase-3 (Cell Signaling Technology, #9664, 1:1,000, MA, United States), and β-actin (Proteintech, #66009–1, 1:5,000, IL, United States).

    Techniques: Comparison

    Protein, intracellular Ca 2+ , and apoptosis levels in hippocampus of rats repeatedly exposed to CBD and/or METH. (A) Levels of DRD1, pMeCP2, and apoptosis-related proteins in hippocampus. (B) Intracellular Ca 2+ level in hippocampus. (C) Apoptosis level in hippocampus. *** p < 0.001 compared with control group, ### p < 0.001 compared with METH group; Tukey HSD post-hoc comparison after significant ANOVA.

    Journal: Frontiers in Pharmacology

    Article Title: Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2

    doi: 10.3389/fphar.2022.972828

    Figure Lengend Snippet: Protein, intracellular Ca 2+ , and apoptosis levels in hippocampus of rats repeatedly exposed to CBD and/or METH. (A) Levels of DRD1, pMeCP2, and apoptosis-related proteins in hippocampus. (B) Intracellular Ca 2+ level in hippocampus. (C) Apoptosis level in hippocampus. *** p < 0.001 compared with control group, ### p < 0.001 compared with METH group; Tukey HSD post-hoc comparison after significant ANOVA.

    Article Snippet: The membranes were blocked with 5% dry skimmed milk in Tris-buffered saline and incubated overnight at 4°C in blocking solution containing primary antibodies against DRD1 (Bio-Techne, #NB110-60017, 1:800, Minneapolis, MN, United States), pMeCP2 (phospho Ser421) (Abcam, #ab254050, 1:1,000, Cambridge, United Kingdom), caspase-8 (Abcam, #ab25901, 1:1,000, Cambridge, United Kingdom), cleaved caspase-8 (Proteintech, #66093-1-Ig, 1:2,000, IL, United States), caspase-3 (Cell Signaling Technology, #9662, 1:1,000, MA, United States), cleaved caspase-3 (Cell Signaling Technology, #9664, 1:1,000, MA, United States), and β-actin (Proteintech, #66009–1, 1:5,000, IL, United States).

    Techniques: Comparison

    Key resources table

    Journal: iScience

    Article Title: Thrombospondin1 mimics rapidly relieve depression via Shank3 dependent uncoupling between dopamine D1 and D2 receptors

    doi: 10.1016/j.isci.2023.106488

    Figure Lengend Snippet: Key resources table

    Article Snippet: D1R , Sigma-Aldrich , Cat# D2944, RRID: AB_1840787.

    Techniques: Recombinant, Magnetic Beads, Real-time Polymerase Chain Reaction, Software