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  • 97
    Bio-Techne corporation 6 cyano 7 nitroquinoxaline 2 3 dione
    6 Cyano 7 Nitroquinoxaline 2 3 Dione, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/6 cyano 7 nitroquinoxaline 2 3 dione/product/Bio-Techne corporation
    Average 97 stars, based on 1 article reviews
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    93
    Alomone Labs cnqx disodium salt
    Cnqx Disodium Salt, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cnqx disodium salt/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
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    cnqx disodium salt - by Bioz Stars, 2024-06
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    cnqx  (Tocris)
    96
    Tocris cnqx
    Cnqx, supplied by Tocris, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    cnqx - by Bioz Stars, 2024-06
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    94
    Tocris cnqx ampa ka receptor antagonist 7
    Cnqx Ampa Ka Receptor Antagonist 7, supplied by Tocris, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    94
    Alomone Labs cnqx
    CCK-positive interneurons also release glutamate onto a subset of postsynaptic targets. A, Examples from a postsynaptic interneuron showing an EPSC (blue arrow) that consistently follows the onset of the light-evoked IPSC in successive light flashes. B, Glutamate receptor blockers <t>CNQX</t> <t>and</t> <t>APV</t> selectively inhibit the EPSC, leaving the IPSC intact. C, The further addition of a GABA-A receptor antagonist to the glutamate blockers eliminates the light-evoked postsynaptic responses completely. D, Histogram of latency from light onset demonstrates the respective timing of the light-evoked EPSCs (orange) and IPSCs (blue). The EPSCs occur later than the IPSCs but within 5–9 ms of light onset. E, Pie chart shows the relative proportions of cell types showing light-evoked EPSCs. Regular spiking (RS) interneurons are the most common type that show these light-evoked glutamatergic EPSCs, with examples also seen in a low threshold (LT) interneuron and in regular (RS) and burst spiking (BS) pyramidal (Pyr)neurons.
    Cnqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cnqx/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
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    cnqx - by Bioz Stars, 2024-06
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    Image Search Results


    CCK-positive interneurons also release glutamate onto a subset of postsynaptic targets. A, Examples from a postsynaptic interneuron showing an EPSC (blue arrow) that consistently follows the onset of the light-evoked IPSC in successive light flashes. B, Glutamate receptor blockers CNQX and APV selectively inhibit the EPSC, leaving the IPSC intact. C, The further addition of a GABA-A receptor antagonist to the glutamate blockers eliminates the light-evoked postsynaptic responses completely. D, Histogram of latency from light onset demonstrates the respective timing of the light-evoked EPSCs (orange) and IPSCs (blue). The EPSCs occur later than the IPSCs but within 5–9 ms of light onset. E, Pie chart shows the relative proportions of cell types showing light-evoked EPSCs. Regular spiking (RS) interneurons are the most common type that show these light-evoked glutamatergic EPSCs, with examples also seen in a low threshold (LT) interneuron and in regular (RS) and burst spiking (BS) pyramidal (Pyr)neurons.

    Journal: The Journal of Neuroscience

    Article Title: Cholecystokinin-Expressing Interneurons of the Medial Prefrontal Cortex Mediate Working Memory Retrieval

    doi: 10.1523/JNEUROSCI.1919-19.2020

    Figure Lengend Snippet: CCK-positive interneurons also release glutamate onto a subset of postsynaptic targets. A, Examples from a postsynaptic interneuron showing an EPSC (blue arrow) that consistently follows the onset of the light-evoked IPSC in successive light flashes. B, Glutamate receptor blockers CNQX and APV selectively inhibit the EPSC, leaving the IPSC intact. C, The further addition of a GABA-A receptor antagonist to the glutamate blockers eliminates the light-evoked postsynaptic responses completely. D, Histogram of latency from light onset demonstrates the respective timing of the light-evoked EPSCs (orange) and IPSCs (blue). The EPSCs occur later than the IPSCs but within 5–9 ms of light onset. E, Pie chart shows the relative proportions of cell types showing light-evoked EPSCs. Regular spiking (RS) interneurons are the most common type that show these light-evoked glutamatergic EPSCs, with examples also seen in a low threshold (LT) interneuron and in regular (RS) and burst spiking (BS) pyramidal (Pyr)neurons.

    Article Snippet: CNQX (Alomone Labs, 20 μ m ) and APV (Alomone Labs, 50 μ m ) were used to block AMPA receptors.

    Techniques: