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  • 90
    Cayman Chemical bml 111
    Bml 111, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bml 111/product/Cayman Chemical
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    bml 111 - by Bioz Stars, 2022-10
    90/100 stars
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    92
    Enzo Biochem bml 111
    Bml 111, supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bml 111/product/Enzo Biochem
    Average 92 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    bml 111 - by Bioz Stars, 2022-10
    92/100 stars
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    92
    Abcam bml 111
    Integrin small molecule inhibitors are as effective as Nintedanib in blocking ECM accumulation. Cells were cultured for 7 days in the presence of Nintedanib (1 µM), Pirfenidone (10 µM), Bindarit (10 µM), RS504393 (10 µM), Beraprost sodium (0.3 µM), IVA337 (3 µM), SB525334 (10 μM), Obeticholic acid (10 µM), Sarpogrelate hydrochloride (1 µM), TRAM34 (10 µM), Nilotinib (0.3 µM), Baricitinib (3 µM), Rapamycin (10 µM), FTY720 (3 µM), Pyridoxamine dihydrochloride (10 µM), <t>BML-111</t> (10 µM), L3223 (10 µM), Enalapril maleate (10 µM), Emricasam (10 µM), CWHM12 (1 µM), C8 (10 µM), Cyclo (RGDyK) (0.04 µM), Cyclo (RGDfK) (0.1 µM), SB273005 (10 µM), Cilengitide (1 µM), DC9711 (10 µM). Cells were then lysed, and the ECM was fixed and stained using a total protein dye or specific antibodies. Graph shows the effect of each small molecule at the dose indicated (highest dose before effect on cell viability was observed) on the total ECM. DMSO control (0.1%) is also shown. Data are represented as fold change from the DMSO control and show the mean with 95% CIs from 2 independent experiments with 4 replicate wells per condition. * p
    Bml 111, supplied by Abcam, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bml 111/product/Abcam
    Average 92 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    bml 111 - by Bioz Stars, 2022-10
    92/100 stars
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    86
    Cayman Chemical 5 s 6 r 7 trihydroxyheptanoic acid methyl ester
    Integrin small molecule inhibitors are as effective as Nintedanib in blocking ECM accumulation. Cells were cultured for 7 days in the presence of Nintedanib (1 µM), Pirfenidone (10 µM), Bindarit (10 µM), RS504393 (10 µM), Beraprost sodium (0.3 µM), IVA337 (3 µM), SB525334 (10 μM), Obeticholic acid (10 µM), Sarpogrelate hydrochloride (1 µM), TRAM34 (10 µM), Nilotinib (0.3 µM), Baricitinib (3 µM), Rapamycin (10 µM), FTY720 (3 µM), Pyridoxamine dihydrochloride (10 µM), <t>BML-111</t> (10 µM), L3223 (10 µM), Enalapril maleate (10 µM), Emricasam (10 µM), CWHM12 (1 µM), C8 (10 µM), Cyclo (RGDyK) (0.04 µM), Cyclo (RGDfK) (0.1 µM), SB273005 (10 µM), Cilengitide (1 µM), DC9711 (10 µM). Cells were then lysed, and the ECM was fixed and stained using a total protein dye or specific antibodies. Graph shows the effect of each small molecule at the dose indicated (highest dose before effect on cell viability was observed) on the total ECM. DMSO control (0.1%) is also shown. Data are represented as fold change from the DMSO control and show the mean with 95% CIs from 2 independent experiments with 4 replicate wells per condition. * p
    5 S 6 R 7 Trihydroxyheptanoic Acid Methyl Ester, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/5 s 6 r 7 trihydroxyheptanoic acid methyl ester/product/Cayman Chemical
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    5 s 6 r 7 trihydroxyheptanoic acid methyl ester - by Bioz Stars, 2022-10
    86/100 stars
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    Image Search Results


    Integrin small molecule inhibitors are as effective as Nintedanib in blocking ECM accumulation. Cells were cultured for 7 days in the presence of Nintedanib (1 µM), Pirfenidone (10 µM), Bindarit (10 µM), RS504393 (10 µM), Beraprost sodium (0.3 µM), IVA337 (3 µM), SB525334 (10 μM), Obeticholic acid (10 µM), Sarpogrelate hydrochloride (1 µM), TRAM34 (10 µM), Nilotinib (0.3 µM), Baricitinib (3 µM), Rapamycin (10 µM), FTY720 (3 µM), Pyridoxamine dihydrochloride (10 µM), BML-111 (10 µM), L3223 (10 µM), Enalapril maleate (10 µM), Emricasam (10 µM), CWHM12 (1 µM), C8 (10 µM), Cyclo (RGDyK) (0.04 µM), Cyclo (RGDfK) (0.1 µM), SB273005 (10 µM), Cilengitide (1 µM), DC9711 (10 µM). Cells were then lysed, and the ECM was fixed and stained using a total protein dye or specific antibodies. Graph shows the effect of each small molecule at the dose indicated (highest dose before effect on cell viability was observed) on the total ECM. DMSO control (0.1%) is also shown. Data are represented as fold change from the DMSO control and show the mean with 95% CIs from 2 independent experiments with 4 replicate wells per condition. * p

    Journal: Nephron. Clinical Practice

    Article Title: Spontaneous Extracellular Matrix Accumulation in a Human in vitro Model of Renal Fibrosis Is Mediated by αV Integrins

    doi: 10.1159/000499506

    Figure Lengend Snippet: Integrin small molecule inhibitors are as effective as Nintedanib in blocking ECM accumulation. Cells were cultured for 7 days in the presence of Nintedanib (1 µM), Pirfenidone (10 µM), Bindarit (10 µM), RS504393 (10 µM), Beraprost sodium (0.3 µM), IVA337 (3 µM), SB525334 (10 μM), Obeticholic acid (10 µM), Sarpogrelate hydrochloride (1 µM), TRAM34 (10 µM), Nilotinib (0.3 µM), Baricitinib (3 µM), Rapamycin (10 µM), FTY720 (3 µM), Pyridoxamine dihydrochloride (10 µM), BML-111 (10 µM), L3223 (10 µM), Enalapril maleate (10 µM), Emricasam (10 µM), CWHM12 (1 µM), C8 (10 µM), Cyclo (RGDyK) (0.04 µM), Cyclo (RGDfK) (0.1 µM), SB273005 (10 µM), Cilengitide (1 µM), DC9711 (10 µM). Cells were then lysed, and the ECM was fixed and stained using a total protein dye or specific antibodies. Graph shows the effect of each small molecule at the dose indicated (highest dose before effect on cell viability was observed) on the total ECM. DMSO control (0.1%) is also shown. Data are represented as fold change from the DMSO control and show the mean with 95% CIs from 2 independent experiments with 4 replicate wells per condition. * p

    Article Snippet: For treatment with small molecule inhibitors, cells were incubated in the presence of nintedanib (Selleckchem), pirfenidone (Sigma-Aldrich), bindarit (Abcam), RS504393 (Sigma-Aldrich), beraprost sodium (Tocris Bioscience), IVA337 (UCB), obeticholic acid (Selleckchem), sarpogrelate hydrochloride (Sigma-Aldrich), TRAM34 (Sigma-Aldrich), nilotinib (Abcam), baricitinib (Selleckchem), rapamycin (Sigma-Aldrich), FTY720 (Sigma-Aldrich), pyridoxamine dihydrochloride (Sigma-Aldrich), BML-111 (Abcam), L3223 (Echelon Biosciences), enalapril maleate (Sigma-Aldrich), emricasam (Selleckchem), CWHM12 (UCB), C8 (UCB), Cyclo (RGDyK) (Selleckchem), Cyclo (RGDfK) (Selleckchem), SB273005 (Selleckchem), cilengitide (Selleckchem) and DC9711 (DC Chemicals) at the indicated concentrations.

    Techniques: Blocking Assay, Cell Culture, Staining