Becton Dickinson
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2023-05
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Santa Cruz Biotechnology
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p22 phox - by Bioz Stars,
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Abcam
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Thermo Fisher
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Sanquin
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Image Search Results

Journal: Experimental and Therapeutic Medicine
Article Title: Ursolic acid suppresses TGF-β1-induced quiescent HSC activation and transformation by inhibiting NADPH oxidase expression and Hedgehog signaling
doi: 10.3892/etm.2017.5001
Figure Lengend Snippet: Effect of ursolic acid (UA) on the NOX subunits and Hh signaling pathway during quiescent hepatic stellate cell (HSC) activation. Quiescent HSCs were stimulated with transforming growth factor (TGF)-β1 (5 µg/l) for 24 h. Protein expression levels of gp91 phox , p67 phox , p22 phox , Rac1, Shh, Smo, and Gli2 were significantly higher than in the control group. Treatment with UA (40 µM) inhibited expression of these proteins. UA and DPI had comparable effects. DPI, diphenyleneiodonium chloride; Shh, sonic hedgehog; Smo, sterol-4-alpha-methyl oxidase; Gli2, Gli family zinc finger 2.
Article Snippet: Dulbecco's modified Eagle's medium (DMEM) was purchased from Thermo Fisher Scientific, Inc. Antibodies against NOX2/gp91 phox ,
Techniques: Activation Assay, Expressing