Journal: Iranian Journal of Medical Sciences
Article Title: Upregulation of Endothelin-1/Endothelin A Receptor Expression Correlates with Heparanase Expression in Ovarian Carcinoma
Figure Lengend Snippet: Based on the immunohistochemical staining of heparanase (black arrow), endothelin A receptor (ET A R) (orange arrow), and Ki-67 (red arrow), overexpression of heparanase and ET A R was detected in the malignant ovarian epithelial tumors (i.e., mucinous [G-I] and serous cystadenocarcinoma [J-L], endometrioid [M-O], and clear cell carcinoma [P-R]). Nevertheless, lesser expression was shown in the benign ovarian epithelial tumors (i.e., mucinous [A-C] and serous [D-F] cystadenoma (magnification ×400).
Article Snippet: The paraffin-embedded tissues were used for immunohistochemistry with heparanase (AB85543, Abcam, dilution 1:200), ETA R (SC33535, Santa Cruz, dilution 1:100), and Ki-67 (CRM 325 B, Biocare Medical, dilution 1:100) antibodies.
Techniques: Immunohistochemistry, Staining, Over Expression, Expressing