RTS-500 Search Results


  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 93
    Alomone Labs snx 482
    <t>SNX-482</t> inhibition of non-L-type I Ca in cultured midbrain DA neurons. A. Representative traces illustrating the inhibition of non-L-type I Ca by 100 nM SNX-482 (red). Cells were initially perfused with a bath solution containing 3 μM isradipine (ISR, black). Full block was obtained using 2 μM Cd 2+ (blue). Square pulses (50 ms) were applied to 0 mV from a holding potential of −70 mV (top) B. Current amplitude values plotted as a function of time. After stabilization of I Ca with ISR (black circles), 100 nM SNX-482 was applied. The remaining currents was blocked by 2 μM Cd 2+ . C. SNX-482 inhibition expressed as % of control I Ca after LTCC block using 3 μM ISR. D. Mean current amplitude at the end of ISR application and at the end of SNX-482 application. Data represent the means ± SEM for the indicated number of experiments (N=4). Statistical significance was determined using paired Student’s t-test: *** p
    Snx 482, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/snx 482/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    snx 482 - by Bioz Stars, 2022-09
    93/100 stars
      Buy from Supplier

    85
    Roche rapid translation system rts 500 e coli hy kit
    <t>SNX-482</t> inhibition of non-L-type I Ca in cultured midbrain DA neurons. A. Representative traces illustrating the inhibition of non-L-type I Ca by 100 nM SNX-482 (red). Cells were initially perfused with a bath solution containing 3 μM isradipine (ISR, black). Full block was obtained using 2 μM Cd 2+ (blue). Square pulses (50 ms) were applied to 0 mV from a holding potential of −70 mV (top) B. Current amplitude values plotted as a function of time. After stabilization of I Ca with ISR (black circles), 100 nM SNX-482 was applied. The remaining currents was blocked by 2 μM Cd 2+ . C. SNX-482 inhibition expressed as % of control I Ca after LTCC block using 3 μM ISR. D. Mean current amplitude at the end of ISR application and at the end of SNX-482 application. Data represent the means ± SEM for the indicated number of experiments (N=4). Statistical significance was determined using paired Student’s t-test: *** p
    Rapid Translation System Rts 500 E Coli Hy Kit, supplied by Roche, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rapid translation system rts 500 e coli hy kit/product/Roche
    Average 85 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rapid translation system rts 500 e coli hy kit - by Bioz Stars, 2022-09
    85/100 stars
      Buy from Supplier

    80
    Roche rts 500 e coli circular template kit
    <t>SNX-482</t> inhibition of non-L-type I Ca in cultured midbrain DA neurons. A. Representative traces illustrating the inhibition of non-L-type I Ca by 100 nM SNX-482 (red). Cells were initially perfused with a bath solution containing 3 μM isradipine (ISR, black). Full block was obtained using 2 μM Cd 2+ (blue). Square pulses (50 ms) were applied to 0 mV from a holding potential of −70 mV (top) B. Current amplitude values plotted as a function of time. After stabilization of I Ca with ISR (black circles), 100 nM SNX-482 was applied. The remaining currents was blocked by 2 μM Cd 2+ . C. SNX-482 inhibition expressed as % of control I Ca after LTCC block using 3 μM ISR. D. Mean current amplitude at the end of ISR application and at the end of SNX-482 application. Data represent the means ± SEM for the indicated number of experiments (N=4). Statistical significance was determined using paired Student’s t-test: *** p
    Rts 500 E Coli Circular Template Kit, supplied by Roche, used in various techniques. Bioz Stars score: 80/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rts 500 e coli circular template kit/product/Roche
    Average 80 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rts 500 e coli circular template kit - by Bioz Stars, 2022-09
    80/100 stars
      Buy from Supplier

    85
    5 PRIME rts 500 wheat germ cecf kit
    <t>SNX-482</t> inhibition of non-L-type I Ca in cultured midbrain DA neurons. A. Representative traces illustrating the inhibition of non-L-type I Ca by 100 nM SNX-482 (red). Cells were initially perfused with a bath solution containing 3 μM isradipine (ISR, black). Full block was obtained using 2 μM Cd 2+ (blue). Square pulses (50 ms) were applied to 0 mV from a holding potential of −70 mV (top) B. Current amplitude values plotted as a function of time. After stabilization of I Ca with ISR (black circles), 100 nM SNX-482 was applied. The remaining currents was blocked by 2 μM Cd 2+ . C. SNX-482 inhibition expressed as % of control I Ca after LTCC block using 3 μM ISR. D. Mean current amplitude at the end of ISR application and at the end of SNX-482 application. Data represent the means ± SEM for the indicated number of experiments (N=4). Statistical significance was determined using paired Student’s t-test: *** p
    Rts 500 Wheat Germ Cecf Kit, supplied by 5 PRIME, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rts 500 wheat germ cecf kit/product/5 PRIME
    Average 85 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rts 500 wheat germ cecf kit - by Bioz Stars, 2022-09
    85/100 stars
      Buy from Supplier

    Image Search Results


    SNX-482 inhibition of non-L-type I Ca in cultured midbrain DA neurons. A. Representative traces illustrating the inhibition of non-L-type I Ca by 100 nM SNX-482 (red). Cells were initially perfused with a bath solution containing 3 μM isradipine (ISR, black). Full block was obtained using 2 μM Cd 2+ (blue). Square pulses (50 ms) were applied to 0 mV from a holding potential of −70 mV (top) B. Current amplitude values plotted as a function of time. After stabilization of I Ca with ISR (black circles), 100 nM SNX-482 was applied. The remaining currents was blocked by 2 μM Cd 2+ . C. SNX-482 inhibition expressed as % of control I Ca after LTCC block using 3 μM ISR. D. Mean current amplitude at the end of ISR application and at the end of SNX-482 application. Data represent the means ± SEM for the indicated number of experiments (N=4). Statistical significance was determined using paired Student’s t-test: *** p

    Journal: bioRxiv

    Article Title: Alternative splicing of auxiliary β2-subunits stabilizes Cav2.3 Ca2+ channel activity in continuously active midbrain dopamine neurons

    doi: 10.1101/2021.02.10.430224

    Figure Lengend Snippet: SNX-482 inhibition of non-L-type I Ca in cultured midbrain DA neurons. A. Representative traces illustrating the inhibition of non-L-type I Ca by 100 nM SNX-482 (red). Cells were initially perfused with a bath solution containing 3 μM isradipine (ISR, black). Full block was obtained using 2 μM Cd 2+ (blue). Square pulses (50 ms) were applied to 0 mV from a holding potential of −70 mV (top) B. Current amplitude values plotted as a function of time. After stabilization of I Ca with ISR (black circles), 100 nM SNX-482 was applied. The remaining currents was blocked by 2 μM Cd 2+ . C. SNX-482 inhibition expressed as % of control I Ca after LTCC block using 3 μM ISR. D. Mean current amplitude at the end of ISR application and at the end of SNX-482 application. Data represent the means ± SEM for the indicated number of experiments (N=4). Statistical significance was determined using paired Student’s t-test: *** p

    Article Snippet: For inhibition experiments, 100 nM SNX-482 (Alomone, Cat # RTS-500 dissolved in ACSF) or 10 µM nifedipine (Alomone, Cat # N-120 diluted into ACSF from a freshly prepared 10 mM stock solution in DMSO) was bath applied (in ACSF).

    Techniques: Inhibition, Cell Culture, Blocking Assay

    SNX-482 effects on pacemaking of cultured mouse midbrain DA neurons. A. Representative recording of spontaneous firing activity of cultured midbrain dopaminergic neurons before, during and after the application (wash-out) of 100 nM SNX-482. Inset (bottom right): overlay of one single AP before (control) and during the application of 100 nM SNX-482. B. Firing frequency [Hz], coefficient of variation of the interspike interval [%], and AHP peak [mV] before (control) and during the application of 100 nM SNX-482. Data represent the means ± SEM for the indicated number of experiments (N=3). Statistical significance was determined using paired Student’s t-test.: *** p

    Journal: bioRxiv

    Article Title: Alternative splicing of auxiliary β2-subunits stabilizes Cav2.3 Ca2+ channel activity in continuously active midbrain dopamine neurons

    doi: 10.1101/2021.02.10.430224

    Figure Lengend Snippet: SNX-482 effects on pacemaking of cultured mouse midbrain DA neurons. A. Representative recording of spontaneous firing activity of cultured midbrain dopaminergic neurons before, during and after the application (wash-out) of 100 nM SNX-482. Inset (bottom right): overlay of one single AP before (control) and during the application of 100 nM SNX-482. B. Firing frequency [Hz], coefficient of variation of the interspike interval [%], and AHP peak [mV] before (control) and during the application of 100 nM SNX-482. Data represent the means ± SEM for the indicated number of experiments (N=3). Statistical significance was determined using paired Student’s t-test.: *** p

    Article Snippet: For inhibition experiments, 100 nM SNX-482 (Alomone, Cat # RTS-500 dissolved in ACSF) or 10 µM nifedipine (Alomone, Cat # N-120 diluted into ACSF from a freshly prepared 10 mM stock solution in DMSO) was bath applied (in ACSF).

    Techniques: Cell Culture, Activity Assay