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    MedChemExpress riociguat
    Post‐mortem computerized tomographic measurement of pulmonary vascular volumes with representative images (a = Sham, b = PE, c = PE+SU5416, d = PE+SU5416+CINA; no image available for PE+SU+RIO). CINA, cinaciguat; PE, pulmonary embolism with microspheres alone; RIO, <t>riociguat.</t> The asterisk indicates significance at p
    Riociguat, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/riociguat/product/MedChemExpress
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    riociguat - by Bioz Stars, 2022-07
    94/100 stars
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    Image Search Results


    Post‐mortem computerized tomographic measurement of pulmonary vascular volumes with representative images (a = Sham, b = PE, c = PE+SU5416, d = PE+SU5416+CINA; no image available for PE+SU+RIO). CINA, cinaciguat; PE, pulmonary embolism with microspheres alone; RIO, riociguat. The asterisk indicates significance at p

    Journal: Physiological Reports

    Article Title: Modulation of soluble guanylate cyclase ameliorates pulmonary hypertension in a rat model of chronic thromboembolic pulmonary hypertension by stimulating angiogenesis). Modulation of soluble guanylate cyclase ameliorates pulmonary hypertension in a rat model of chronic thromboembolic pulmonary hypertension by stimulating angiogenesis

    doi: 10.14814/phy2.15156

    Figure Lengend Snippet: Post‐mortem computerized tomographic measurement of pulmonary vascular volumes with representative images (a = Sham, b = PE, c = PE+SU5416, d = PE+SU5416+CINA; no image available for PE+SU+RIO). CINA, cinaciguat; PE, pulmonary embolism with microspheres alone; RIO, riociguat. The asterisk indicates significance at p

    Article Snippet: CINA (Tocris 6052 or BAY 582667; gifted from Bayer‐AG) or RIO (MedChem Express, #HY‐14779) was administered to rats by subcutaneous injection twice daily with 0.83 ml/kg chemical dissolved in DMSO at 3 mg/ml (2.5 mg/kg/injection final dose).

    Techniques:

    Geltrex tube assays of rat endothelial cells treated with SU5416 plus cinaciguat (CINA) or riociguat (RIO). Panel a: Phase‐contrast images of representative wells from triplicate assays of pulmonary microvascular endothelial cells (PMVECs) (25k/well) treated with the indicated supplements. Control cells were incubated with M1266 basal medium containing glutamine and antibiotic‐antimycotic mix without growth factors or serum. DMSO was added at a concentration of 0.2% in control samples. SU5416, CINA, and RIO dissolved in DMSO were added to M1266 basal medium at the indicated concentrations. Panel b: Angiogenesis Analyzer metrics of PMVECs treated in Panel a. Representative metrics in which SU5416+CINA treatments were significantly different from SU5416 alone are shown ( p

    Journal: Physiological Reports

    Article Title: Modulation of soluble guanylate cyclase ameliorates pulmonary hypertension in a rat model of chronic thromboembolic pulmonary hypertension by stimulating angiogenesis). Modulation of soluble guanylate cyclase ameliorates pulmonary hypertension in a rat model of chronic thromboembolic pulmonary hypertension by stimulating angiogenesis

    doi: 10.14814/phy2.15156

    Figure Lengend Snippet: Geltrex tube assays of rat endothelial cells treated with SU5416 plus cinaciguat (CINA) or riociguat (RIO). Panel a: Phase‐contrast images of representative wells from triplicate assays of pulmonary microvascular endothelial cells (PMVECs) (25k/well) treated with the indicated supplements. Control cells were incubated with M1266 basal medium containing glutamine and antibiotic‐antimycotic mix without growth factors or serum. DMSO was added at a concentration of 0.2% in control samples. SU5416, CINA, and RIO dissolved in DMSO were added to M1266 basal medium at the indicated concentrations. Panel b: Angiogenesis Analyzer metrics of PMVECs treated in Panel a. Representative metrics in which SU5416+CINA treatments were significantly different from SU5416 alone are shown ( p

    Article Snippet: CINA (Tocris 6052 or BAY 582667; gifted from Bayer‐AG) or RIO (MedChem Express, #HY‐14779) was administered to rats by subcutaneous injection twice daily with 0.83 ml/kg chemical dissolved in DMSO at 3 mg/ml (2.5 mg/kg/injection final dose).

    Techniques: Incubation, Concentration Assay