This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to

Calcitonin/Calcitonin Gene Related Peptide/CGRP/CALCA causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Katacalcin (a cleavage product) is a

Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicule. Target gene of Wnt signaling.

AKT1S1 is a proline-rich substrate of AKT that binds 14-3-3 protein when phosphorylated. [supplied by OMIM].