A-285 Search Results


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    • arcaine sulfate  (Alomone Labs)
    94
    Alomone Labs arcaine sulfate
    ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by <t>arcaine</t> (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p<0.05 when compared to control group (in d ). *** indicates p< 0.001 when compared to control group exposed to the same spermine concentration. n.s., not significant. hGluN2B- wt , n=9; hGluN2B-G689C, n=10; hGluN2B-G689S, n=9.
    Arcaine Sulfate, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/arcaine sulfate/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    arcaine sulfate - by Bioz Stars, 2023-02
    94/100 stars
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    collagenase a 285 solution termed adf  (Thermo Fisher)
    86
    Thermo Fisher collagenase a 285 solution termed adf
    ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by <t>arcaine</t> (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p<0.05 when compared to control group (in d ). *** indicates p< 0.001 when compared to control group exposed to the same spermine concentration. n.s., not significant. hGluN2B- wt , n=9; hGluN2B-G689C, n=10; hGluN2B-G689S, n=9.
    Collagenase A 285 Solution Termed Adf, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/collagenase a 285 solution termed adf/product/Thermo Fisher
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    collagenase a 285 solution termed adf - by Bioz Stars, 2023-02
    86/100 stars
    		  Buy from Supplier
    a285  (Sanofi)
    86
    Sanofi a285
    ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by <t>arcaine</t> (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p<0.05 when compared to control group (in d ). *** indicates p< 0.001 when compared to control group exposed to the same spermine concentration. n.s., not significant. hGluN2B- wt , n=9; hGluN2B-G689C, n=10; hGluN2B-G689S, n=9.
    A285, supplied by Sanofi, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/a285/product/Sanofi
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    a285 - by Bioz Stars, 2023-02
    86/100 stars
    		  Buy from Supplier
    bmj a285 pmcid pmc2432122 hannah j durrington  (Wellcome Trust)
    86
    Wellcome Trust bmj a285 pmcid pmc2432122 hannah j durrington
    ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by <t>arcaine</t> (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p<0.05 when compared to control group (in d ). *** indicates p< 0.001 when compared to control group exposed to the same spermine concentration. n.s., not significant. hGluN2B- wt , n=9; hGluN2B-G689C, n=10; hGluN2B-G689S, n=9.
    Bmj A285 Pmcid Pmc2432122 Hannah J Durrington, supplied by Wellcome Trust, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bmj a285 pmcid pmc2432122 hannah j durrington/product/Wellcome Trust
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    bmj a285 pmcid pmc2432122 hannah j durrington - by Bioz Stars, 2023-02
    86/100 stars
    		  Buy from Supplier
    rocco m a285 w po40022 roche  (Roche)
    86
    Roche rocco m a285 w po40022 roche
    ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by <t>arcaine</t> (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p<0.05 when compared to control group (in d ). *** indicates p< 0.001 when compared to control group exposed to the same spermine concentration. n.s., not significant. hGluN2B- wt , n=9; hGluN2B-G689C, n=10; hGluN2B-G689S, n=9.
    Rocco M A285 W Po40022 Roche, supplied by Roche, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rocco m a285 w po40022 roche/product/Roche
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rocco m a285 w po40022 roche - by Bioz Stars, 2023-02
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by arcaine (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p<0.05 when compared to control group (in d ). *** indicates p< 0.001 when compared to control group exposed to the same spermine concentration. n.s., not significant. hGluN2B- wt , n=9; hGluN2B-G689C, n=10; hGluN2B-G689S, n=9.

    Journal: eLife

    Article Title: Two de novo GluN2B mutations affect multiple NMDAR-functions and instigate severe pediatric encephalopathy

    doi: 10.7554/eLife.67555

    Figure Lengend Snippet: ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by arcaine (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p<0.05 when compared to control group (in d ). *** indicates p< 0.001 when compared to control group exposed to the same spermine concentration. n.s., not significant. hGluN2B- wt , n=9; hGluN2B-G689C, n=10; hGluN2B-G689S, n=9.

    Article Snippet: Arcaine sulfate was purchased from Alomone labs (Cat. # 14923-17-2).

    Techniques: Expressing, Blocking Assay, Concentration Assay