Journal: Turkish Archives of Otorhinolaryngology

Article Title: Antimicrobial Activity of Garlic Derivatives on Common Causative Microorganisms of the External Ear Canal and Chronic Middle Ear Infections

doi: 10.5152/tao.2019.4413

Figure Lengend Snippet: Antifungal activity (MIC and MFC) of the allicin, S-allylcysteine, S-allylmercaptocysteine, and diallyl disulfide

Article Snippet: The MICs of SAMC were > 640 μg/mL for the tested bacteria and yeasts. table ft1 table-wrap mode="anchored" t5 caption a7 S-Allylcysteine Allicin S-Allylmercaptocysteine Diallyl disulfide Control antibiotic (Ciprofloxacin) MIC MBC MIC MBC MIC MBC MIC MBC MIC E. coli ATCC 25922 0.125 0.250 0.125 0.250 >640 >640 80 160 0.125 K. pneumoniae ATCC 700603 20 40 20 40 >640 >640 40 80 0.250 P. aeruginosa ATCC 27853 80 160 80 160 >640 >640 160 320 1 A. baumannii ATCC 19606 20 40 20 40 >640 >640 40 80 0.03 S. aureus ATCC 29213 10 20 10 20 >640 >640 80 160 0.06 E. faecium ATCC BAA2127 5 20 5 20 >640 >640 40 160 0.06 Open in a separate window MIC: minimum inhibitory concentrations (μg/mL); MBC: minimum bactericidal concentration (μg/mL) Antibacterial activity (MIC and MBC) of the allicin, S-allylcysteine, S-allylmercaptocysteine, and diallyl disulfide table ft1 table-wrap mode="anchored" t5 Table 2 caption a7 S-Allylcysteine Allicin S-Allylmercaptocysteine Diallyl disulfide Control antifungal (fluconazole) MIC MFC MIC MFC MIC MFC MIC MFC MIC C. albicans ATCC 102316 80 160 80 160 >640 >640 20 40 0.5 C. tropicalis ATCC 13803 40 80 40 80 >640 >640 40 80 0.5 Open in a separate window MIC: minimum inhibitory concentrations (μg/mL); MFC: minimum fungicidal concentration (μg/mL) Antifungal activity (MIC and MFC) of the allicin, S-allylcysteine, S-allylmercaptocysteine, and diallyl disulfide No antimicrobial activities were detected at the tested concentrations of methanol, HCL and DMSO.

Techniques: Activity Assay