6113 Search Results


  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 93
    Toronto Research Chemicals neat α cypermethrin
    Top DE Genes Induced by Main Effects and Interaction of <t> Cypermethrin </t> and Stress a
    Neat α Cypermethrin, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/neat α cypermethrin/product/Toronto Research Chemicals
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    neat α cypermethrin - by Bioz Stars, 2024-05
    93/100 stars
      Buy from Supplier

    93
    Bio-Techne corporation ferroptosis liproxstatin 1
    Top DE Genes Induced by Main Effects and Interaction of <t> Cypermethrin </t> and Stress a
    Ferroptosis Liproxstatin 1, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ferroptosis liproxstatin 1/product/Bio-Techne corporation
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    ferroptosis liproxstatin 1 - by Bioz Stars, 2024-05
    93/100 stars
      Buy from Supplier

    93
    DSMZ bacillus thuringiensis 1
    Top DE Genes Induced by Main Effects and Interaction of <t> Cypermethrin </t> and Stress a
    Bacillus Thuringiensis 1, supplied by DSMZ, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bacillus thuringiensis 1/product/DSMZ
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    bacillus thuringiensis 1 - by Bioz Stars, 2024-05
    93/100 stars
      Buy from Supplier

    93
    DSMZ parvimonas micra dsm20468
    Top DE Genes Induced by Main Effects and Interaction of <t> Cypermethrin </t> and Stress a
    Parvimonas Micra Dsm20468, supplied by DSMZ, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/parvimonas micra dsm20468/product/DSMZ
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    parvimonas micra dsm20468 - by Bioz Stars, 2024-05
    93/100 stars
      Buy from Supplier

    93
    DSMZ blautia producta dsm3507
    a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta <t>DSM3507,</t> G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.
    Blautia Producta Dsm3507, supplied by DSMZ, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/blautia producta dsm3507/product/DSMZ
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    blautia producta dsm3507 - by Bioz Stars, 2024-05
    93/100 stars
      Buy from Supplier

    Image Search Results


    Top DE Genes Induced by Main Effects and Interaction of  Cypermethrin  and Stress a

    Journal: Toxicological Sciences

    Article Title: Combined Maternal Exposure to Cypermethrin and Stress Affect Embryonic Brain and Placental Outcomes in Mice

    doi: 10.1093/toxsci/kfaa040

    Figure Lengend Snippet: Top DE Genes Induced by Main Effects and Interaction of Cypermethrin and Stress a

    Article Snippet: Neat α-cypermethrin (98%, Toronto Research Chemicals, North York, Canada) for the animal studies was further purified by recrystallization in isopropanol to 99% purity (based on relative peak area).

    Techniques:

    Pathway Enrichment Analysis of Genes Altered by  Cypermethrin,  Stress, and Combination a

    Journal: Toxicological Sciences

    Article Title: Combined Maternal Exposure to Cypermethrin and Stress Affect Embryonic Brain and Placental Outcomes in Mice

    doi: 10.1093/toxsci/kfaa040

    Figure Lengend Snippet: Pathway Enrichment Analysis of Genes Altered by Cypermethrin, Stress, and Combination a

    Article Snippet: Neat α-cypermethrin (98%, Toronto Research Chemicals, North York, Canada) for the animal studies was further purified by recrystallization in isopropanol to 99% purity (based on relative peak area).

    Techniques: Activation Assay, Homologous Recombination

    Maternal cypermethrin exposure impaired tangential migration of GABAergic progenitors. A, Representative pictures highlighting the furthest extent of GABAergic progenitor tangential migration (arrows). B, Cypermethrin impaired GABAergic progenitor tangential migration. C, Ingenuity Pathway Analysis Pathway Comparison Analysis assessing canonical pathways enriched by cypermethrin (NS cyp), stress (PS veh), and the combination of the 2 treatments (PS cyp) in isolated GABAergic progenitors. D, Cypermethrin-induced delays in GABAergic migration were correlated with fetal growth restriction (r = .9598), despite no significant correlation in vehicle-treated embryos (r = .4936). Means ± SEMs are shown. n = 5–7 litters per treatment group (*p < .05 by post hoc tests) (##p < .01 main effect by 2-way ANOVA). Abbreviations: NS, nonstressed; PS, prenatal stress.

    Journal: Toxicological Sciences

    Article Title: Combined Maternal Exposure to Cypermethrin and Stress Affect Embryonic Brain and Placental Outcomes in Mice

    doi: 10.1093/toxsci/kfaa040

    Figure Lengend Snippet: Maternal cypermethrin exposure impaired tangential migration of GABAergic progenitors. A, Representative pictures highlighting the furthest extent of GABAergic progenitor tangential migration (arrows). B, Cypermethrin impaired GABAergic progenitor tangential migration. C, Ingenuity Pathway Analysis Pathway Comparison Analysis assessing canonical pathways enriched by cypermethrin (NS cyp), stress (PS veh), and the combination of the 2 treatments (PS cyp) in isolated GABAergic progenitors. D, Cypermethrin-induced delays in GABAergic migration were correlated with fetal growth restriction (r = .9598), despite no significant correlation in vehicle-treated embryos (r = .4936). Means ± SEMs are shown. n = 5–7 litters per treatment group (*p < .05 by post hoc tests) (##p < .01 main effect by 2-way ANOVA). Abbreviations: NS, nonstressed; PS, prenatal stress.

    Article Snippet: Neat α-cypermethrin (98%, Toronto Research Chemicals, North York, Canada) for the animal studies was further purified by recrystallization in isopropanol to 99% purity (based on relative peak area).

    Techniques: Migration, Isolation

    Maternal stress and cypermethrin exposure reduced maternal and fetal weight gain. A, Treatment changed maternal weight gain throughout pregnancy (E0–E14). B, Maternal weight gain specifically during the treatment period (E11–E14) was decreased by stress, cypermethrin, or combined exposure. C, Fetal body weight was reduced by cypermethrin exposure alone or in combination with stress. Means ± SEMs are shown. n = 5–7 litters per treatment group (*p < .05, **p < .01, ***p < .001 by post hoc tests) (##p < .01, ###p < .001 main effect by 2-way ANOVA). Abbreviations: NS, nonstressed; PS, prenatal stress.

    Journal: Toxicological Sciences

    Article Title: Combined Maternal Exposure to Cypermethrin and Stress Affect Embryonic Brain and Placental Outcomes in Mice

    doi: 10.1093/toxsci/kfaa040

    Figure Lengend Snippet: Maternal stress and cypermethrin exposure reduced maternal and fetal weight gain. A, Treatment changed maternal weight gain throughout pregnancy (E0–E14). B, Maternal weight gain specifically during the treatment period (E11–E14) was decreased by stress, cypermethrin, or combined exposure. C, Fetal body weight was reduced by cypermethrin exposure alone or in combination with stress. Means ± SEMs are shown. n = 5–7 litters per treatment group (*p < .05, **p < .01, ***p < .001 by post hoc tests) (##p < .01, ###p < .001 main effect by 2-way ANOVA). Abbreviations: NS, nonstressed; PS, prenatal stress.

    Article Snippet: Neat α-cypermethrin (98%, Toronto Research Chemicals, North York, Canada) for the animal studies was further purified by recrystallization in isopropanol to 99% purity (based on relative peak area).

    Techniques:

    Maternal cypermethrin and stress exposure impaired forebrain growth and GABAergic system development. A, Representative pictures highlighting ganglionic eminence proliferative zone (white outline). B, Cypermethrin reduced forebrain volume. C, Cypermethrin increased ganglionic eminence proliferative zone volume. (D) Cypermethrin increased ventral forebrain gene expression of cell proliferation marker Ki-67 and (E) stem cell marker Sox2. (F) Cypermethrin increased gene expression of apoptotic inhibitor Bcl2 in the ventral forebrain (G) but had no effect on gene expression of proapoptotic regulator Bax. Means ± SEMs are shown. n = 5–7 litters per treatment group (*p < .05, **p < .01 by post hoc tests) (#p < .05, ##p < .01 main effect by 2-way ANOVA). Abbreviations: G.E., ganglionic eminence; NS, nonstressed; PS, prenatal stress.

    Journal: Toxicological Sciences

    Article Title: Combined Maternal Exposure to Cypermethrin and Stress Affect Embryonic Brain and Placental Outcomes in Mice

    doi: 10.1093/toxsci/kfaa040

    Figure Lengend Snippet: Maternal cypermethrin and stress exposure impaired forebrain growth and GABAergic system development. A, Representative pictures highlighting ganglionic eminence proliferative zone (white outline). B, Cypermethrin reduced forebrain volume. C, Cypermethrin increased ganglionic eminence proliferative zone volume. (D) Cypermethrin increased ventral forebrain gene expression of cell proliferation marker Ki-67 and (E) stem cell marker Sox2. (F) Cypermethrin increased gene expression of apoptotic inhibitor Bcl2 in the ventral forebrain (G) but had no effect on gene expression of proapoptotic regulator Bax. Means ± SEMs are shown. n = 5–7 litters per treatment group (*p < .05, **p < .01 by post hoc tests) (#p < .05, ##p < .01 main effect by 2-way ANOVA). Abbreviations: G.E., ganglionic eminence; NS, nonstressed; PS, prenatal stress.

    Article Snippet: Neat α-cypermethrin (98%, Toronto Research Chemicals, North York, Canada) for the animal studies was further purified by recrystallization in isopropanol to 99% purity (based on relative peak area).

    Techniques: Expressing, Marker

    Maternal cypermethrin and stress altered microglia morphology in the E14 dorsal forebrain. A, Representative pictures of E14 microglia morphologies: (1) Multivacuolated, with multiple vacuoles and/or pyknotic nuclei, (2) Ameboid, with no processes and normal nucleus, (3) Transitional, with 1 process and normal nucleus, (4) Ramified, with 2 or more processes and normal nuclei (high magnification). Representative picture of the forebrain stained for Iba1 to the right (low magnification). B, Cypermethrin increased percentage of ameboid microglia. C, No effect for either treatment on transitional microglia. D, Cypermethrin decreased the percentage of ramified microglia. E, Cypermethrin alone, but not in combination with stress, increased the percentage of multivacuolated microglia. F, No effect for either treatment on total microglia density. Means ± SEMs are shown. n = 5–7 litters per treatment group (**p < .01 by post hoc tests) (#p < .05, ##p < .01 main effect by 2-way ANOVA) (^p < .05 interaction by 2-way ANOVA). Abbreviations: NS, nonstressed; PS, prenatal stress.

    Journal: Toxicological Sciences

    Article Title: Combined Maternal Exposure to Cypermethrin and Stress Affect Embryonic Brain and Placental Outcomes in Mice

    doi: 10.1093/toxsci/kfaa040

    Figure Lengend Snippet: Maternal cypermethrin and stress altered microglia morphology in the E14 dorsal forebrain. A, Representative pictures of E14 microglia morphologies: (1) Multivacuolated, with multiple vacuoles and/or pyknotic nuclei, (2) Ameboid, with no processes and normal nucleus, (3) Transitional, with 1 process and normal nucleus, (4) Ramified, with 2 or more processes and normal nuclei (high magnification). Representative picture of the forebrain stained for Iba1 to the right (low magnification). B, Cypermethrin increased percentage of ameboid microglia. C, No effect for either treatment on transitional microglia. D, Cypermethrin decreased the percentage of ramified microglia. E, Cypermethrin alone, but not in combination with stress, increased the percentage of multivacuolated microglia. F, No effect for either treatment on total microglia density. Means ± SEMs are shown. n = 5–7 litters per treatment group (**p < .01 by post hoc tests) (#p < .05, ##p < .01 main effect by 2-way ANOVA) (^p < .05 interaction by 2-way ANOVA). Abbreviations: NS, nonstressed; PS, prenatal stress.

    Article Snippet: Neat α-cypermethrin (98%, Toronto Research Chemicals, North York, Canada) for the animal studies was further purified by recrystallization in isopropanol to 99% purity (based on relative peak area).

    Techniques: Staining

    Maternal stress increased concentration of cypermethrin in maternal serum and altered maternal hepatic expression of cytochrome P450 enzymes after cypermethrin exposure. A, Restraint stress increased the concentration of cypermethrin in maternal serum. B, Cypermethrin levels in amniotic fluid were below the limit of quantification. C, Stress suppressed cypermethrin-dependent upregulation of hepatic Cyp1a1 expression. D, Stress reduced hepatic expression of Cyp1a2. E, Stress reduced hepatic expression of Cyp2b10. F–H, Stress or cypermethrin did not affect hepatic expression of Cyp2e1, Cyp3a11, or Cyp3a41b. Means ± SEMs are shown. n = 5–7 litters per treatment group (*p < .05 by Mann-Whitney or post hoc tests) (#p < .05, ##p < .01 main effect by 2-way ANOVA) (^p < .05 interaction by 2-way ANOVA). Abbreviations: NS, nonstressed; PS, prenatal stress.

    Journal: Toxicological Sciences

    Article Title: Combined Maternal Exposure to Cypermethrin and Stress Affect Embryonic Brain and Placental Outcomes in Mice

    doi: 10.1093/toxsci/kfaa040

    Figure Lengend Snippet: Maternal stress increased concentration of cypermethrin in maternal serum and altered maternal hepatic expression of cytochrome P450 enzymes after cypermethrin exposure. A, Restraint stress increased the concentration of cypermethrin in maternal serum. B, Cypermethrin levels in amniotic fluid were below the limit of quantification. C, Stress suppressed cypermethrin-dependent upregulation of hepatic Cyp1a1 expression. D, Stress reduced hepatic expression of Cyp1a2. E, Stress reduced hepatic expression of Cyp2b10. F–H, Stress or cypermethrin did not affect hepatic expression of Cyp2e1, Cyp3a11, or Cyp3a41b. Means ± SEMs are shown. n = 5–7 litters per treatment group (*p < .05 by Mann-Whitney or post hoc tests) (#p < .05, ##p < .01 main effect by 2-way ANOVA) (^p < .05 interaction by 2-way ANOVA). Abbreviations: NS, nonstressed; PS, prenatal stress.

    Article Snippet: Neat α-cypermethrin (98%, Toronto Research Chemicals, North York, Canada) for the animal studies was further purified by recrystallization in isopropanol to 99% purity (based on relative peak area).

    Techniques: Concentration Assay, Expressing, MANN-WHITNEY

    Maternal cypermethrin and stress altered placental oxidative stress and gene expression. A, Cypermethrin increased lipid peroxidation marker malondialdehyde in placental tissue. B, Neither treatment significantly affected placental reduced thiol content. C, Placental endothelin-1 expression increased in response to both cypermethrin and stress. (D) Cypermethrin treatment increased placental gene expression of several angiogenic genes responsive to oxidative stress, including Hif-1alpha, (E) heme oxygenase 1, and (F) Vegfr2. Means ± SEMs are shown. n = 4–7 litters per treatment group (*p < .05, **p < .01, ***p < .001 by post hoc tests) (#p < .05, ##p < .01, ###p < .001 main effect by 2-way ANOVA). Abbreviations: NS, nonstressed; PS, prenatal stress.

    Journal: Toxicological Sciences

    Article Title: Combined Maternal Exposure to Cypermethrin and Stress Affect Embryonic Brain and Placental Outcomes in Mice

    doi: 10.1093/toxsci/kfaa040

    Figure Lengend Snippet: Maternal cypermethrin and stress altered placental oxidative stress and gene expression. A, Cypermethrin increased lipid peroxidation marker malondialdehyde in placental tissue. B, Neither treatment significantly affected placental reduced thiol content. C, Placental endothelin-1 expression increased in response to both cypermethrin and stress. (D) Cypermethrin treatment increased placental gene expression of several angiogenic genes responsive to oxidative stress, including Hif-1alpha, (E) heme oxygenase 1, and (F) Vegfr2. Means ± SEMs are shown. n = 4–7 litters per treatment group (*p < .05, **p < .01, ***p < .001 by post hoc tests) (#p < .05, ##p < .01, ###p < .001 main effect by 2-way ANOVA). Abbreviations: NS, nonstressed; PS, prenatal stress.

    Article Snippet: Neat α-cypermethrin (98%, Toronto Research Chemicals, North York, Canada) for the animal studies was further purified by recrystallization in isopropanol to 99% purity (based on relative peak area).

    Techniques: Expressing, Marker

    Maternal cypermethrin and stress altered placental gene expression of nutrient transporters. A, Cypermethrin increased gene expression of Snat1. B, Cypermethrin increased expression of Glut1. C, Cypermethrin and stress had interacting effects on placental Glut3 expression. Means ± SEMs are shown. n = 5–7 litters per treatment group (*p < .05 by post hoc tests) (#p < .05, ##p < .01 main effect by 2-way ANOVA) (^p < .05 interaction by 2-way ANOVA). Abbreviations: NS, nonstressed; PS, prenatal stress.

    Journal: Toxicological Sciences

    Article Title: Combined Maternal Exposure to Cypermethrin and Stress Affect Embryonic Brain and Placental Outcomes in Mice

    doi: 10.1093/toxsci/kfaa040

    Figure Lengend Snippet: Maternal cypermethrin and stress altered placental gene expression of nutrient transporters. A, Cypermethrin increased gene expression of Snat1. B, Cypermethrin increased expression of Glut1. C, Cypermethrin and stress had interacting effects on placental Glut3 expression. Means ± SEMs are shown. n = 5–7 litters per treatment group (*p < .05 by post hoc tests) (#p < .05, ##p < .01 main effect by 2-way ANOVA) (^p < .05 interaction by 2-way ANOVA). Abbreviations: NS, nonstressed; PS, prenatal stress.

    Article Snippet: Neat α-cypermethrin (98%, Toronto Research Chemicals, North York, Canada) for the animal studies was further purified by recrystallization in isopropanol to 99% purity (based on relative peak area).

    Techniques: Expressing

    a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta DSM3507, G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.

    Journal: Nature microbiology

    Article Title: Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria

    doi: 10.1038/s41564-019-0596-1

    Figure Lengend Snippet: a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta DSM3507, G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.

    Article Snippet: Blautia producta DSM3507 and Lactonifactor longoviformis DSM17459 T were purchased from DSMZ and de novo sequenced as before with draft genomes available ( ).

    Techniques: Quantitation Assay, MANN-WHITNEY, Two Tailed Test, Mass Spectrometry