42902 Search Results


mycobacterium tuberculosis sumu003  (ATCC)
90
ATCC mycobacterium tuberculosis sumu003
Mycobacterium Tuberculosis Sumu003, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mycobacterium tuberculosis sumu003/product/ATCC
Average 90 stars, based on 1 article reviews
mycobacterium tuberculosis sumu003 - by Bioz Stars, 2025-07
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nbi 42902  (Neurocrine Biosciences)
86
Neurocrine Biosciences nbi 42902
Competition binding of GnRH peptides to wild-type and Phe178(4.64) mutant receptors. COS-7 cells transfected with wild-type or mutant receptors were preincubated with (F178L) or without (F178A and F178W) 1 μm <t>NBI-42902</t> for 48 h and then washed prior to the binding assay. Details are given under “Experimental Procedures.” Normalized competitive binding of GnRH I (A), GnRH II (B), and [Phe3]GnRH I (C) at the wild-type ■, F174A ▴, F178L ●, and F178W ⧫ receptors. Results are representative experiments repeated at least three times with essentially the same results. Points are mean ± S.E. of triplicate measurements.
Nbi 42902, supplied by Neurocrine Biosciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nbi 42902/product/Neurocrine Biosciences
Average 86 stars, based on 1 article reviews
nbi 42902 - by Bioz Stars, 2025-07
86/100 stars
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nbi 42902 1 2 6 difluorobenzyl  (Neurocrine Biosciences)
86
Neurocrine Biosciences nbi 42902 1 2 6 difluorobenzyl
Competition binding of GnRH peptides to wild-type and Phe178(4.64) mutant receptors. COS-7 cells transfected with wild-type or mutant receptors were preincubated with (F178L) or without (F178A and F178W) 1 μm <t>NBI-42902</t> for 48 h and then washed prior to the binding assay. Details are given under “Experimental Procedures.” Normalized competitive binding of GnRH I (A), GnRH II (B), and [Phe3]GnRH I (C) at the wild-type ■, F174A ▴, F178L ●, and F178W ⧫ receptors. Results are representative experiments repeated at least three times with essentially the same results. Points are mean ± S.E. of triplicate measurements.
Nbi 42902 1 2 6 Difluorobenzyl, supplied by Neurocrine Biosciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nbi 42902 1 2 6 difluorobenzyl/product/Neurocrine Biosciences
Average 86 stars, based on 1 article reviews
nbi 42902 1 2 6 difluorobenzyl - by Bioz Stars, 2025-07
86/100 stars
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va cervical dysplasia 703 506 9460 nbi 42902 neurocrine biosciences breast  (Neurocrine Biosciences)
86
Neurocrine Biosciences va cervical dysplasia 703 506 9460 nbi 42902 neurocrine biosciences breast
Competition binding of GnRH peptides to wild-type and Phe178(4.64) mutant receptors. COS-7 cells transfected with wild-type or mutant receptors were preincubated with (F178L) or without (F178A and F178W) 1 μm <t>NBI-42902</t> for 48 h and then washed prior to the binding assay. Details are given under “Experimental Procedures.” Normalized competitive binding of GnRH I (A), GnRH II (B), and [Phe3]GnRH I (C) at the wild-type ■, F174A ▴, F178L ●, and F178W ⧫ receptors. Results are representative experiments repeated at least three times with essentially the same results. Points are mean ± S.E. of triplicate measurements.
Va Cervical Dysplasia 703 506 9460 Nbi 42902 Neurocrine Biosciences Breast, supplied by Neurocrine Biosciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/va cervical dysplasia 703 506 9460 nbi 42902 neurocrine biosciences breast/product/Neurocrine Biosciences
Average 86 stars, based on 1 article reviews
va cervical dysplasia 703 506 9460 nbi 42902 neurocrine biosciences breast - by Bioz Stars, 2025-07
86/100 stars
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shcdh1 b  (Addgene inc)
88
Addgene inc shcdh1 b
Competition binding of GnRH peptides to wild-type and Phe178(4.64) mutant receptors. COS-7 cells transfected with wild-type or mutant receptors were preincubated with (F178L) or without (F178A and F178W) 1 μm <t>NBI-42902</t> for 48 h and then washed prior to the binding assay. Details are given under “Experimental Procedures.” Normalized competitive binding of GnRH I (A), GnRH II (B), and [Phe3]GnRH I (C) at the wild-type ■, F174A ▴, F178L ●, and F178W ⧫ receptors. Results are representative experiments repeated at least three times with essentially the same results. Points are mean ± S.E. of triplicate measurements.
Shcdh1 B, supplied by Addgene inc, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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shcdh1 b - by Bioz Stars, 2025-07
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Image Search Results


Competition binding of GnRH peptides to wild-type and Phe178(4.64) mutant receptors. COS-7 cells transfected with wild-type or mutant receptors were preincubated with (F178L) or without (F178A and F178W) 1 μm NBI-42902 for 48 h and then washed prior to the binding assay. Details are given under “Experimental Procedures.” Normalized competitive binding of GnRH I (A), GnRH II (B), and [Phe3]GnRH I (C) at the wild-type ■, F174A ▴, F178L ●, and F178W ⧫ receptors. Results are representative experiments repeated at least three times with essentially the same results. Points are mean ± S.E. of triplicate measurements.

Journal: The Journal of Biological Chemistry

Article Title: Role of the Transmembrane Domain 4/Extracellular Loop 2 Junction of the Human Gonadotropin-releasing Hormone Receptor in Ligand Binding and Receptor Conformational Selection

doi: 10.1074/jbc.M111.240341

Figure Lengend Snippet: Competition binding of GnRH peptides to wild-type and Phe178(4.64) mutant receptors. COS-7 cells transfected with wild-type or mutant receptors were preincubated with (F178L) or without (F178A and F178W) 1 μm NBI-42902 for 48 h and then washed prior to the binding assay. Details are given under “Experimental Procedures.” Normalized competitive binding of GnRH I (A), GnRH II (B), and [Phe3]GnRH I (C) at the wild-type ■, F174A ▴, F178L ●, and F178W ⧫ receptors. Results are representative experiments repeated at least three times with essentially the same results. Points are mean ± S.E. of triplicate measurements.

Article Snippet: We greatly appreciate the gift of NBI-42902, provided by Neurocrine Biosciences.

Techniques: Binding Assay, Mutagenesis, Transfection

Effects of mutations on the functional responses. A, effects of mutational changes in receptor binding affinity (pIC50 values) on the functional potency (pEC50 values). Inset, mutants of Phe178(4.64) only: GnRH I, ●; GnRH II, △. B, effects of mutations on the maximum signaling efficacy. *, denotes mutants pretreated with NBI-42902. For detailed results see Tables 1 and ​and33.

Journal: The Journal of Biological Chemistry

Article Title: Role of the Transmembrane Domain 4/Extracellular Loop 2 Junction of the Human Gonadotropin-releasing Hormone Receptor in Ligand Binding and Receptor Conformational Selection

doi: 10.1074/jbc.M111.240341

Figure Lengend Snippet: Effects of mutations on the functional responses. A, effects of mutational changes in receptor binding affinity (pIC50 values) on the functional potency (pEC50 values). Inset, mutants of Phe178(4.64) only: GnRH I, ●; GnRH II, △. B, effects of mutations on the maximum signaling efficacy. *, denotes mutants pretreated with NBI-42902. For detailed results see Tables 1 and ​and33.

Article Snippet: We greatly appreciate the gift of NBI-42902, provided by Neurocrine Biosciences.

Techniques: Functional Assay, Binding Assay