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    Sino Biological sars cov 2 2019 ncov spike neutralizing antibody mouse mab
    NP-based inhibition assay. (a) Left: The structure of neutralizing antibody (top) bound to <t>SARS-CoV-2</t> Spike RBD (bottom, green). Right: Schematic diagram of the inhibition assay depicting blocking of the interaction between RBD and ACE2 and the resulting inhibition of energy transfer from QD to AuNP. (b) PL recovery of QD 514 -RBD in the presence of neutralizing antibody Ab1. (c) Inhibition test using anti-Spike antibody without neutralizing ability, showing almost no PL recovery of QD 514 -RBD. (d) Calculated EC 50 s for neutralizing antibodies Ab1 and Ab2 were 60 nM and 125 nM with R 2 > 99%, respectively.
    Sars Cov 2 2019 Ncov Spike Neutralizing Antibody Mouse Mab, supplied by Sino Biological, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/sars cov 2 2019 ncov spike neutralizing antibody mouse mab/product/Sino Biological
    Average 96 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    sars cov 2 2019 ncov spike neutralizing antibody mouse mab - by Bioz Stars, 2021-07
    96/100 stars
      Buy from Supplier

    94
    Sino Biological sars cov 2 2019 ncov spike s1 mfc recombinant protein covid 19 spike s1 research
    NP-based inhibition assay. (a) Left: The structure of neutralizing antibody (top) bound to <t>SARS-CoV-2</t> Spike RBD (bottom, green). Right: Schematic diagram of the inhibition assay depicting blocking of the interaction between RBD and ACE2 and the resulting inhibition of energy transfer from QD to AuNP. (b) PL recovery of QD 514 -RBD in the presence of neutralizing antibody Ab1. (c) Inhibition test using anti-Spike antibody without neutralizing ability, showing almost no PL recovery of QD 514 -RBD. (d) Calculated EC 50 s for neutralizing antibodies Ab1 and Ab2 were 60 nM and 125 nM with R 2 > 99%, respectively.
    Sars Cov 2 2019 Ncov Spike S1 Mfc Recombinant Protein Covid 19 Spike S1 Research, supplied by Sino Biological, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/sars cov 2 2019 ncov spike s1 mfc recombinant protein covid 19 spike s1 research/product/Sino Biological
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    sars cov 2 2019 ncov spike s1 mfc recombinant protein covid 19 spike s1 research - by Bioz Stars, 2021-07
    94/100 stars
      Buy from Supplier

    Image Search Results


    NP-based inhibition assay. (a) Left: The structure of neutralizing antibody (top) bound to SARS-CoV-2 Spike RBD (bottom, green). Right: Schematic diagram of the inhibition assay depicting blocking of the interaction between RBD and ACE2 and the resulting inhibition of energy transfer from QD to AuNP. (b) PL recovery of QD 514 -RBD in the presence of neutralizing antibody Ab1. (c) Inhibition test using anti-Spike antibody without neutralizing ability, showing almost no PL recovery of QD 514 -RBD. (d) Calculated EC 50 s for neutralizing antibodies Ab1 and Ab2 were 60 nM and 125 nM with R 2 > 99%, respectively.

    Journal: ACS Nano

    Article Title: Quantum Dot-Conjugated SARS-CoV-2 Spike Pseudo-Virions Enable Tracking of Angiotensin Converting Enzyme 2 Binding and Endocytosis

    doi: 10.1021/acsnano.0c05975

    Figure Lengend Snippet: NP-based inhibition assay. (a) Left: The structure of neutralizing antibody (top) bound to SARS-CoV-2 Spike RBD (bottom, green). Right: Schematic diagram of the inhibition assay depicting blocking of the interaction between RBD and ACE2 and the resulting inhibition of energy transfer from QD to AuNP. (b) PL recovery of QD 514 -RBD in the presence of neutralizing antibody Ab1. (c) Inhibition test using anti-Spike antibody without neutralizing ability, showing almost no PL recovery of QD 514 -RBD. (d) Calculated EC 50 s for neutralizing antibodies Ab1 and Ab2 were 60 nM and 125 nM with R 2 > 99%, respectively.

    Article Snippet: SARS-CoV S1-His (40150-V08B1), SARS-CoV-2 S1S2 ECD-His (40589-V08B1), SARS-CoV-2 S1-His (40591-V08H), SARS-CoV-2 RBD-His (40592-V08B), anti-SARS-CoV-2 S1 neutralizing antibody mouse mAb Ab1 (40591-MM43), and anti-SARS-CoV-2 RBD neutralizing antibody mouse mAb Ab2 (40592-MM57) were purchased from Sino Biological.

    Techniques: Inhibition, Blocking Assay

    Illustrations of the interactions involving SARS-CoV-2 RBD. ( A ) Interactions between the RBD portion of SARS-CoV-2 and the ACE2 receptor on the host cell can be impaired via neutralizing antibodies. ( B ) Interactions between HiBiT-RBD and LgBiT lead to the generation of bioluminescence signal after substrate digestion.

    Journal: Nanomaterials

    Article Title: A High-Throughput NanoBiT-Based Serological Assay Detects SARS-CoV-2 Seroconversion

    doi: 10.3390/nano11030807

    Figure Lengend Snippet: Illustrations of the interactions involving SARS-CoV-2 RBD. ( A ) Interactions between the RBD portion of SARS-CoV-2 and the ACE2 receptor on the host cell can be impaired via neutralizing antibodies. ( B ) Interactions between HiBiT-RBD and LgBiT lead to the generation of bioluminescence signal after substrate digestion.

    Article Snippet: High Accuracy of the HiBiT-RBD Reporter for SARS-CoV-2 Neutralizing Antibodies with Considerable AffinityThe HiBiT-RBD reporter was initially validated by testing two different commercial SARS-CoV-2 neutralizing antibodies, SinoBiological 40592 and ActiveMotif 1414, in comparison to control IgG ( A,B).

    Techniques:

    The detection of antibodies using the HiBiT-RBD serological assay. ( A ) Illustration of the NanoBiT serological assay. ( B ) High signal intensity and detection of the SARS-CoV-2 neutralizing antibodies compared to no signal for the control antibody. ( C ) Presence of signal in all positive patient cases and no false-positive results in negative samples. This experiment performed in the 96 well plates which showed the compatibility of the assay for high through put screening.

    Journal: Nanomaterials

    Article Title: A High-Throughput NanoBiT-Based Serological Assay Detects SARS-CoV-2 Seroconversion

    doi: 10.3390/nano11030807

    Figure Lengend Snippet: The detection of antibodies using the HiBiT-RBD serological assay. ( A ) Illustration of the NanoBiT serological assay. ( B ) High signal intensity and detection of the SARS-CoV-2 neutralizing antibodies compared to no signal for the control antibody. ( C ) Presence of signal in all positive patient cases and no false-positive results in negative samples. This experiment performed in the 96 well plates which showed the compatibility of the assay for high through put screening.

    Article Snippet: High Accuracy of the HiBiT-RBD Reporter for SARS-CoV-2 Neutralizing Antibodies with Considerable AffinityThe HiBiT-RBD reporter was initially validated by testing two different commercial SARS-CoV-2 neutralizing antibodies, SinoBiological 40592 and ActiveMotif 1414, in comparison to control IgG ( A,B).

    Techniques: Serologic Assay