4-aminoantipyrine Search Results


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  • 96
    Millipore 4 aminoantipyrine
    Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were pretreated (Pretreat) iv with vehicle (V) or with 2 mg/kg SR59230A (SRA) 15 min before iv treatment (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), <t>4-aminoantipyrine</t> (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 6 animals per group. *P
    4 Aminoantipyrine, supplied by Millipore, used in various techniques. Bioz Stars score: 96/100, based on 602 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/4 aminoantipyrine/product/Millipore
    Average 96 stars, based on 602 article reviews
    Price from $9.99 to $1999.99
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    91
    Roche 4 aminoantipyrine
    Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were pretreated (Pretreat) iv with vehicle (V) or with 2 mg/kg SR59230A (SRA) 15 min before iv treatment (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), <t>4-aminoantipyrine</t> (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 6 animals per group. *P
    4 Aminoantipyrine, supplied by Roche, used in various techniques. Bioz Stars score: 91/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/4 aminoantipyrine/product/Roche
    Average 91 stars, based on 5 article reviews
    Price from $9.99 to $1999.99
    4 aminoantipyrine - by Bioz Stars, 2020-08
    91/100 stars
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    91
    Thermo Fisher 4 aminoantipyrine
    Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were pretreated (Pretreat) iv with vehicle (V) or with 2 mg/kg SR59230A (SRA) 15 min before iv treatment (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), <t>4-aminoantipyrine</t> (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 6 animals per group. *P
    4 Aminoantipyrine, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 91/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/4 aminoantipyrine/product/Thermo Fisher
    Average 91 stars, based on 8 article reviews
    Price from $9.99 to $1999.99
    4 aminoantipyrine - by Bioz Stars, 2020-08
    91/100 stars
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    91
    Nacalai 4 aminoantipyrine
    Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were pretreated (Pretreat) iv with vehicle (V) or with 2 mg/kg SR59230A (SRA) 15 min before iv treatment (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), <t>4-aminoantipyrine</t> (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 6 animals per group. *P
    4 Aminoantipyrine, supplied by Nacalai, used in various techniques. Bioz Stars score: 91/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/4 aminoantipyrine/product/Nacalai
    Average 91 stars, based on 10 article reviews
    Price from $9.99 to $1999.99
    4 aminoantipyrine - by Bioz Stars, 2020-08
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    93
    Fluka Chemie 4 aminoantipyrine
    Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were pretreated (Pretreat) iv with vehicle (V) or with 2 mg/kg SR59230A (SRA) 15 min before iv treatment (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), <t>4-aminoantipyrine</t> (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 6 animals per group. *P
    4 Aminoantipyrine, supplied by Fluka Chemie, used in various techniques. Bioz Stars score: 93/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/4 aminoantipyrine/product/Fluka Chemie
    Average 93 stars, based on 2 article reviews
    Price from $9.99 to $1999.99
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    85
    Thermo Fisher 4 aminoantipyrine hydrochloride
    Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were pretreated (Pretreat) iv with vehicle (V) or with 2 mg/kg SR59230A (SRA) 15 min before iv treatment (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), <t>4-aminoantipyrine</t> (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 6 animals per group. *P
    4 Aminoantipyrine Hydrochloride, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    92
    Kishida Chemical 4 aminoantipyrine
    Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were pretreated (Pretreat) iv with vehicle (V) or with 2 mg/kg SR59230A (SRA) 15 min before iv treatment (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), <t>4-aminoantipyrine</t> (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 6 animals per group. *P
    4 Aminoantipyrine, supplied by Kishida Chemical, used in various techniques. Bioz Stars score: 92/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/4 aminoantipyrine/product/Kishida Chemical
    Average 92 stars, based on 2 article reviews
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    91
    J&K Scientific 4 aminoantipyrine
    Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were pretreated (Pretreat) iv with vehicle (V) or with 2 mg/kg SR59230A (SRA) 15 min before iv treatment (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), <t>4-aminoantipyrine</t> (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 6 animals per group. *P
    4 Aminoantipyrine, supplied by J&K Scientific, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/4 aminoantipyrine/product/J&K Scientific
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
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    Image Search Results


    Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were pretreated (Pretreat) iv with vehicle (V) or with 2 mg/kg SR59230A (SRA) 15 min before iv treatment (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), 4-aminoantipyrine (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 6 animals per group. *P

    Journal: Brazilian Journal of Medical and Biological Research

    Article Title: Effect of selective β-adrenoceptor blockade and surgical resection of the celiac-superior mesenteric ganglion complex on delayed liquid gastric emptying induced by dipyrone, 4-aminoantipyrine, and antipyrine in rats

    doi: 10.1590/1414-431X20155011

    Figure Lengend Snippet: Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were pretreated (Pretreat) iv with vehicle (V) or with 2 mg/kg SR59230A (SRA) 15 min before iv treatment (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), 4-aminoantipyrine (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 6 animals per group. *P

    Article Snippet: Dipyrone, 4-aminoantipyrine, antipyrine, atenolol, butoxamine, SR59230A, and dimethyl sulfoxide (DMSO) were purchased from Sigma, USA.

    Techniques:

    Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were first subjected to surgical resection of the celiac-superior mesenteric ganglion complex (GLX) or to sham surgery (SH) and treated iv (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), 4-aminoantipyrine (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 10 animals per group. *P

    Journal: Brazilian Journal of Medical and Biological Research

    Article Title: Effect of selective β-adrenoceptor blockade and surgical resection of the celiac-superior mesenteric ganglion complex on delayed liquid gastric emptying induced by dipyrone, 4-aminoantipyrine, and antipyrine in rats

    doi: 10.1590/1414-431X20155011

    Figure Lengend Snippet: Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were first subjected to surgical resection of the celiac-superior mesenteric ganglion complex (GLX) or to sham surgery (SH) and treated iv (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), 4-aminoantipyrine (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 10 animals per group. *P

    Article Snippet: Dipyrone, 4-aminoantipyrine, antipyrine, atenolol, butoxamine, SR59230A, and dimethyl sulfoxide (DMSO) were purchased from Sigma, USA.

    Techniques:

    Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were pretreated (Pretreat) iv with vehicle (V), 30 mg/kg atenolol (ATE), or 25 mg/kg butoxamine (BUT) 15 min before iv treatment (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), 4-aminoantipyrine (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 6 animals per group. *P

    Journal: Brazilian Journal of Medical and Biological Research

    Article Title: Effect of selective β-adrenoceptor blockade and surgical resection of the celiac-superior mesenteric ganglion complex on delayed liquid gastric emptying induced by dipyrone, 4-aminoantipyrine, and antipyrine in rats

    doi: 10.1590/1414-431X20155011

    Figure Lengend Snippet: Gastric retention (%) of a saline test meal provided to rats by gavage. The rats were pretreated (Pretreat) iv with vehicle (V), 30 mg/kg atenolol (ATE), or 25 mg/kg butoxamine (BUT) 15 min before iv treatment (Treat) with saline (S), 240 µmol/kg dipyrone (Dp), 4-aminoantipyrine (AA), or antipyrine (At). The test meal was administered 10 min after treatment. Data are reported as means±SE for 6 animals per group. *P

    Article Snippet: Dipyrone, 4-aminoantipyrine, antipyrine, atenolol, butoxamine, SR59230A, and dimethyl sulfoxide (DMSO) were purchased from Sigma, USA.

    Techniques:

    Dose-response curve for basophil activation test performed with metamizole metabolites. 4-methylamino antipyrine (MAA), 4-aminoantipyrine (AA), 4-acetylamino antipyrine (AAA) and 4-formylamino antipyrine (FAA). Results are expressed as the mean + SD of stimulation index (SI). Patients (N = 16) and healthy controls (N = 15).

    Journal: Scientific Reports

    Article Title: Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole

    doi: 10.1038/srep23845

    Figure Lengend Snippet: Dose-response curve for basophil activation test performed with metamizole metabolites. 4-methylamino antipyrine (MAA), 4-aminoantipyrine (AA), 4-acetylamino antipyrine (AAA) and 4-formylamino antipyrine (FAA). Results are expressed as the mean + SD of stimulation index (SI). Patients (N = 16) and healthy controls (N = 15).

    Article Snippet: Metabolites obtention Metamizole metabolites were purified from human urine samples, obtained from healthy individuals who received an oral dose of 575 mg of metamizole (Nolotil®, Boehringer Ingelheim, Barcelona, Spain), with the exception of 4-aminoantipyrine (AA) which was purchased from SIGMA chemical Co. (St. Louis, MO, USA).

    Techniques: Activation Assay

    Main metabolic pathways of metamizole in humans. Metabolites are: 4-methylamino antipyrine (MAA), 4-aminoantipyrine (AA), 4-acetylamino antipyrine (AAA) and 4-formylamino antipyrine (FAA).

    Journal: Scientific Reports

    Article Title: Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole

    doi: 10.1038/srep23845

    Figure Lengend Snippet: Main metabolic pathways of metamizole in humans. Metabolites are: 4-methylamino antipyrine (MAA), 4-aminoantipyrine (AA), 4-acetylamino antipyrine (AAA) and 4-formylamino antipyrine (FAA).

    Article Snippet: Metabolites obtention Metamizole metabolites were purified from human urine samples, obtained from healthy individuals who received an oral dose of 575 mg of metamizole (Nolotil®, Boehringer Ingelheim, Barcelona, Spain), with the exception of 4-aminoantipyrine (AA) which was purchased from SIGMA chemical Co. (St. Louis, MO, USA).

    Techniques:

    Representative dot plot graph of patient 4 showing basophil activation with negative control, positive controls (fMLP and anti-IgE), metamizole and metamizole metabolites: 4-methylamino antipyrine (MAA), 4-aminoantipyrine (AA), 4-acetylamino antipyrine (AAA) and 4-formylamino antipyrine (FAA) at 0.25 mg/mL. The figure also shows the stimulation index (SI) values for each determination.

    Journal: Scientific Reports

    Article Title: Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole

    doi: 10.1038/srep23845

    Figure Lengend Snippet: Representative dot plot graph of patient 4 showing basophil activation with negative control, positive controls (fMLP and anti-IgE), metamizole and metamizole metabolites: 4-methylamino antipyrine (MAA), 4-aminoantipyrine (AA), 4-acetylamino antipyrine (AAA) and 4-formylamino antipyrine (FAA) at 0.25 mg/mL. The figure also shows the stimulation index (SI) values for each determination.

    Article Snippet: Metabolites obtention Metamizole metabolites were purified from human urine samples, obtained from healthy individuals who received an oral dose of 575 mg of metamizole (Nolotil®, Boehringer Ingelheim, Barcelona, Spain), with the exception of 4-aminoantipyrine (AA) which was purchased from SIGMA chemical Co. (St. Louis, MO, USA).

    Techniques: Activation Assay, Negative Control

    Sodium chlorate attenuates neuronal polarization of neural precursor cell-derived neurons. (A-D, G)  Photomicrographs of differentiated NPCs stained for cleaved Caspase3, MAP2, and Tau after seven days of differentiation.  (A-D)  NaClO 3  treatment did not result in an increased apoptotic cell death after seven days. However, in line with an increased percentage of βIII-Tubulin-positive neurons after four days, the relative number of MAP2-positive cells was enhanced in response to NaClO 3 .  (E)  The quantification of MAP2-positive neurons revealed a significant increase in the relative amount of neurons in NaClO 3  treated cultures (n = 4;  P  = 0.015).  (F, G)  Interestingly, the percentage of Tau-positive cells among MAP2-positive neurons was strongly reduced after NaClO 3  treatment (n = 4;  P  = 0.002). To visualize the nuclei the cells were counterstained with Hoechst 33528. Scale bar: 50 μm (A-D), 25 μm (G).

    Journal: Neural Development

    Article Title: Normal sulfation levels regulate spinal cord neural precursor cell proliferation and differentiation

    doi: 10.1186/1749-8104-7-20

    Figure Lengend Snippet: Sodium chlorate attenuates neuronal polarization of neural precursor cell-derived neurons. (A-D, G) Photomicrographs of differentiated NPCs stained for cleaved Caspase3, MAP2, and Tau after seven days of differentiation. (A-D) NaClO 3 treatment did not result in an increased apoptotic cell death after seven days. However, in line with an increased percentage of βIII-Tubulin-positive neurons after four days, the relative number of MAP2-positive cells was enhanced in response to NaClO 3 . (E) The quantification of MAP2-positive neurons revealed a significant increase in the relative amount of neurons in NaClO 3 treated cultures (n = 4; P  = 0.015). (F, G) Interestingly, the percentage of Tau-positive cells among MAP2-positive neurons was strongly reduced after NaClO 3 treatment (n = 4; P  = 0.002). To visualize the nuclei the cells were counterstained with Hoechst 33528. Scale bar: 50 μm (A-D), 25 μm (G).

    Article Snippet: Hoechst 33528 (Sigma) was included (diluted 1:105 in PBS), to additionally label the nuclei.

    Techniques: Derivative Assay, Staining

    Sodium chlorate efficiently reduces the expression level of the sulfation-dependent 473HD-epitope. (A) Western blot analysis of neurosphere detergent extracts, showing a reduced 473HD expression level upon NaClO 3 treatment. The expression level of different RPTPβ/ζ isoforms, known 473HD carrier proteins, did not appear to be changed in the presence of NaClO 3 . (B) Immunohistochemical detection of the 473HD-epitope and RPTPβ/ζ isoforms on neurosphere cryosections confirmed the reduced 473HD expression levels in NaClO 3 -treated cultures. Here, the immunoreactivity for the 473HD carrier proteins seemed to be enhanced. Hoechst 33528 was used to visualize the cell nuclei. Scale bar: 50 μm.

    Journal: Neural Development

    Article Title: Normal sulfation levels regulate spinal cord neural precursor cell proliferation and differentiation

    doi: 10.1186/1749-8104-7-20

    Figure Lengend Snippet: Sodium chlorate efficiently reduces the expression level of the sulfation-dependent 473HD-epitope. (A) Western blot analysis of neurosphere detergent extracts, showing a reduced 473HD expression level upon NaClO 3 treatment. The expression level of different RPTPβ/ζ isoforms, known 473HD carrier proteins, did not appear to be changed in the presence of NaClO 3 . (B) Immunohistochemical detection of the 473HD-epitope and RPTPβ/ζ isoforms on neurosphere cryosections confirmed the reduced 473HD expression levels in NaClO 3 -treated cultures. Here, the immunoreactivity for the 473HD carrier proteins seemed to be enhanced. Hoechst 33528 was used to visualize the cell nuclei. Scale bar: 50 μm.

    Article Snippet: Hoechst 33528 (Sigma) was included (diluted 1:105 in PBS), to additionally label the nuclei.

    Techniques: Expressing, Western Blot, Immunohistochemistry

    The 473HD epitope is expressed by neural precursor cells during embryonic mouse spinal cord development. (A)  Schematic drawing of frontal E13.5 spinal cord sections, illustrating the spinal cord region shown in B-D.  (B-D)  Photomicrographs of frontal spinal cord sections stained against the 473HD- epitope and the NPC marker Nestin, showing the colocalization of the 473HD- epitope with Nestin-positive NPC processes around the central canal.  (E-H)  Photomicrographs of acutely dissociated spinal cord cells stained against the 473HD-epitope in combination with either the NPC markers Nestin, BLBP and GLAST or the neuronal marker βIII-Tubulin. The 473HD-epitope was exclusively expressed by NPCs. In contrast, we never observed any neuronal expression of the 473HD-epitope.  (I)  Quantification of double immunopositive cells. At E13.5, the percentage of 473HD-positive cells that also expressed one of the NPC markers was relatively low. The relative amount of 473HD-and-Nestin-positive cells peaked at E15.5. In contrast the 473HD-and-BLBP-positive and the 473HD-and-GLAST-positive populations gradually increased towards the end of embryogenesis.  (J)  Quantification of 473HD-positive cells throughout embryonic spinal cord development, showing the gradual increase of 473HD-positive cells between E12.5 and E18.5. To visualize the nuclei, the cells were counterstained with Hoechst 33528. Scale bar: 50 μm (B-D), 25 μm (E-H).

    Journal: Neural Development

    Article Title: Normal sulfation levels regulate spinal cord neural precursor cell proliferation and differentiation

    doi: 10.1186/1749-8104-7-20

    Figure Lengend Snippet: The 473HD epitope is expressed by neural precursor cells during embryonic mouse spinal cord development. (A) Schematic drawing of frontal E13.5 spinal cord sections, illustrating the spinal cord region shown in B-D. (B-D) Photomicrographs of frontal spinal cord sections stained against the 473HD- epitope and the NPC marker Nestin, showing the colocalization of the 473HD- epitope with Nestin-positive NPC processes around the central canal. (E-H) Photomicrographs of acutely dissociated spinal cord cells stained against the 473HD-epitope in combination with either the NPC markers Nestin, BLBP and GLAST or the neuronal marker βIII-Tubulin. The 473HD-epitope was exclusively expressed by NPCs. In contrast, we never observed any neuronal expression of the 473HD-epitope. (I) Quantification of double immunopositive cells. At E13.5, the percentage of 473HD-positive cells that also expressed one of the NPC markers was relatively low. The relative amount of 473HD-and-Nestin-positive cells peaked at E15.5. In contrast the 473HD-and-BLBP-positive and the 473HD-and-GLAST-positive populations gradually increased towards the end of embryogenesis. (J) Quantification of 473HD-positive cells throughout embryonic spinal cord development, showing the gradual increase of 473HD-positive cells between E12.5 and E18.5. To visualize the nuclei, the cells were counterstained with Hoechst 33528. Scale bar: 50 μm (B-D), 25 μm (E-H).

    Article Snippet: Hoechst 33528 (Sigma) was included (diluted 1:105 in PBS), to additionally label the nuclei.

    Techniques: Staining, Marker, Expressing