4 cholesten 3 one Steraloids Inc Search Results


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    steraloids inc 4 cholesten 3 one
    Hepatic mRNA expression levels of several enzymes involved in bile acid biosynthesis are altered in the Cyp27a1 −/− mouse. Relative hepatic RNA levels were determined by Northern analysis from male, mixed-strain, wild-type and Cyp27a1 −/− mice fed a standard rodent diet. The values shown in boxes represent the mean ± SEM of the fold change in mRNA levels ( n = 6 mice per genotype). Bile acid intermediates that would be predicted to accumulate upstream of CYP3A11 because of these changes in enzyme levels include the following: 1 , 7α-hydroxycholesterol (5-cholesten-3β,7α-diol); 2 , <t>7α-hydroxy-4-cholesten-3-one</t> (4-cholesten-7α-ol-3-one); 3 , 5β-cholestan-3α,7α,12α-triol; 4 , 4-cholesten-3-one; and 5 , cholestanol (5α-cholestan-3β-ol).
    4 Cholesten 3 One, supplied by steraloids inc, used in various techniques. Bioz Stars score: 92/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    4 cholesten 3 one - by Bioz Stars, 2020-04
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    84
    steraloids inc 4 cholesten 3 one chne
    Hepatic mRNA expression levels of several enzymes involved in bile acid biosynthesis are altered in the Cyp27a1 −/− mouse. Relative hepatic RNA levels were determined by Northern analysis from male, mixed-strain, wild-type and Cyp27a1 −/− mice fed a standard rodent diet. The values shown in boxes represent the mean ± SEM of the fold change in mRNA levels ( n = 6 mice per genotype). Bile acid intermediates that would be predicted to accumulate upstream of CYP3A11 because of these changes in enzyme levels include the following: 1 , 7α-hydroxycholesterol (5-cholesten-3β,7α-diol); 2 , <t>7α-hydroxy-4-cholesten-3-one</t> (4-cholesten-7α-ol-3-one); 3 , 5β-cholestan-3α,7α,12α-triol; 4 , 4-cholesten-3-one; and 5 , cholestanol (5α-cholestan-3β-ol).
    4 Cholesten 3 One Chne, supplied by steraloids inc, used in various techniques. Bioz Stars score: 84/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    85
    steraloids inc 7α hydroxy 4 cholesten 3 one
    Levels of cholestanol and <t>7α-hydroxy-4-cholesten-3-one</t> (C4) in female wild-type (WT) and CYP27KO mice (A) in plasma. B: Cerebrum cholestanol levels and plasma 7α-hydroxy-4-cholesten-3-one levels shown in the same diagrams. Number of mice, used to measure 7α-hydroxy-4-cholesten-3-one levels in plasma, per group were: WT and KO; ctrl n4 (pool) and n3, cholestyramine n4 (pool) and n3, cholic acid n5 and n5). Number of mice, used to measure cholestanol levels in plasma and cerebrum, per group were: WT and KO; ctrl n4 and n5, cholestyramine n4 and n3, cholic acid n5 and n5.
    7α Hydroxy 4 Cholesten 3 One, supplied by steraloids inc, used in various techniques. Bioz Stars score: 85/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    steraloids inc 4 cholesten 3 one 25s carboxylic acid
    Levels of cholestanol and <t>7α-hydroxy-4-cholesten-3-one</t> (C4) in female wild-type (WT) and CYP27KO mice (A) in plasma. B: Cerebrum cholestanol levels and plasma 7α-hydroxy-4-cholesten-3-one levels shown in the same diagrams. Number of mice, used to measure 7α-hydroxy-4-cholesten-3-one levels in plasma, per group were: WT and KO; ctrl n4 (pool) and n3, cholestyramine n4 (pool) and n3, cholic acid n5 and n5). Number of mice, used to measure cholestanol levels in plasma and cerebrum, per group were: WT and KO; ctrl n4 and n5, cholestyramine n4 and n3, cholic acid n5 and n5.
    4 Cholesten 3 One 25s Carboxylic Acid, supplied by steraloids inc, used in various techniques. Bioz Stars score: 84/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    93
    steraloids inc cholestenone
    Levels of cholestanol and <t>7α-hydroxy-4-cholesten-3-one</t> (C4) in female wild-type (WT) and CYP27KO mice (A) in plasma. B: Cerebrum cholestanol levels and plasma 7α-hydroxy-4-cholesten-3-one levels shown in the same diagrams. Number of mice, used to measure 7α-hydroxy-4-cholesten-3-one levels in plasma, per group were: WT and KO; ctrl n4 (pool) and n3, cholestyramine n4 (pool) and n3, cholic acid n5 and n5). Number of mice, used to measure cholestanol levels in plasma and cerebrum, per group were: WT and KO; ctrl n4 and n5, cholestyramine n4 and n3, cholic acid n5 and n5.
    Cholestenone, supplied by steraloids inc, used in various techniques. Bioz Stars score: 93/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Hepatic mRNA expression levels of several enzymes involved in bile acid biosynthesis are altered in the Cyp27a1 −/− mouse. Relative hepatic RNA levels were determined by Northern analysis from male, mixed-strain, wild-type and Cyp27a1 −/− mice fed a standard rodent diet. The values shown in boxes represent the mean ± SEM of the fold change in mRNA levels ( n = 6 mice per genotype). Bile acid intermediates that would be predicted to accumulate upstream of CYP3A11 because of these changes in enzyme levels include the following: 1 , 7α-hydroxycholesterol (5-cholesten-3β,7α-diol); 2 , 7α-hydroxy-4-cholesten-3-one (4-cholesten-7α-ol-3-one); 3 , 5β-cholestan-3α,7α,12α-triol; 4 , 4-cholesten-3-one; and 5 , cholestanol (5α-cholestan-3β-ol).

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor

    doi: 10.1073/pnas.0237082100

    Figure Lengend Snippet: Hepatic mRNA expression levels of several enzymes involved in bile acid biosynthesis are altered in the Cyp27a1 −/− mouse. Relative hepatic RNA levels were determined by Northern analysis from male, mixed-strain, wild-type and Cyp27a1 −/− mice fed a standard rodent diet. The values shown in boxes represent the mean ± SEM of the fold change in mRNA levels ( n = 6 mice per genotype). Bile acid intermediates that would be predicted to accumulate upstream of CYP3A11 because of these changes in enzyme levels include the following: 1 , 7α-hydroxycholesterol (5-cholesten-3β,7α-diol); 2 , 7α-hydroxy-4-cholesten-3-one (4-cholesten-7α-ol-3-one); 3 , 5β-cholestan-3α,7α,12α-triol; 4 , 4-cholesten-3-one; and 5 , cholestanol (5α-cholestan-3β-ol).

    Article Snippet: 5-Cholesten-3β 7α-diol (7α-OH-cholesterol), 4-cholesten-7α-ol-3-one (7α-OH-4-cholesten-3-one), and 4-cholesten-3-one were purchased from Steraloids (Newport, RI).

    Techniques: Expressing, Northern Blot, Mouse Assay

    Levels of cholestanol and 7α-hydroxy-4-cholesten-3-one (C4) in female wild-type (WT) and CYP27KO mice (A) in plasma. B: Cerebrum cholestanol levels and plasma 7α-hydroxy-4-cholesten-3-one levels shown in the same diagrams. Number of mice, used to measure 7α-hydroxy-4-cholesten-3-one levels in plasma, per group were: WT and KO; ctrl n4 (pool) and n3, cholestyramine n4 (pool) and n3, cholic acid n5 and n5). Number of mice, used to measure cholestanol levels in plasma and cerebrum, per group were: WT and KO; ctrl n4 and n5, cholestyramine n4 and n3, cholic acid n5 and n5.

    Journal: Journal of Lipid Research

    Article Title: On the mechanism of accumulation of cholestanol in the brain of mice with a disruption of sterol 27-hydroxylase

    doi: 10.1194/jlr.M008326

    Figure Lengend Snippet: Levels of cholestanol and 7α-hydroxy-4-cholesten-3-one (C4) in female wild-type (WT) and CYP27KO mice (A) in plasma. B: Cerebrum cholestanol levels and plasma 7α-hydroxy-4-cholesten-3-one levels shown in the same diagrams. Number of mice, used to measure 7α-hydroxy-4-cholesten-3-one levels in plasma, per group were: WT and KO; ctrl n4 (pool) and n3, cholestyramine n4 (pool) and n3, cholic acid n5 and n5). Number of mice, used to measure cholestanol levels in plasma and cerebrum, per group were: WT and KO; ctrl n4 and n5, cholestyramine n4 and n3, cholic acid n5 and n5.

    Article Snippet: 7α-Hydroxy-4-cholesten-3-one was obtained from Steraloids.

    Techniques: Mouse Assay