Journal: Tetrahedron

Article Title: Enantioselective Transesterification Catalysis by Nanosized Serine Protease Subtilisin Carlsberg Particles in Tetrahydrofuran

doi: 10.1016/j.tet.2010.01.053

Figure Lengend Snippet: Results of the computational modeling of the tetrahedral intermediates of ( R )- (A) and ( S )-4-methyl-4-phenyl-2-pentanol (B). It is apparent that only the S -enantiomer side chain comfortably fits into the substrate binding pocket (residues shown in green).

Article Snippet: Subtilisin Carlsberg (SC), MβCD, 2-butanol ( 1 ), 2-pentanol ( 2 ), 2-hexanol ( 3 ), 2-heptanol ( 4 ), 2-octanol ( 5 ), 3-methyl-2-butanol ( 6 ), 4-methyl-2-pentanol ( 7 ), 5-methyl-2-hexanol ( 8 ), 6-methyl-2-heptanol ( 9 ), 4-phenyl-2-butanol ( 10 ), 4,4-dimethyl-2-pentanol ( 11 ), 4-methyl-4-phenyl-2-pentanol ( 12 ), 1-phenyl-1-propanol ( 13 ), and 1-p-tolyl-1-propanol ( 14 ) were from Sigma-Aldrich (St. Louis, MO).

Techniques: Binding Assay

Journal:

Article Title: Initial Studies Using Aliphatic β-Nitro Alcohols for Therapeutic Corneal Cross-Linking

doi: 10.1167/iovs.08-2202

Figure Lengend Snippet: Stiffening effect induced by short-chain aliphatic β -nitro alcohols. Porcine cornea samples were reacted as described for . ( A ) 2-nitroethanol, ( B ) 2-nitro-1-propanol, and ( C ) 3-nitro-2-pentanol cross-linked samples all showed significant

Article Snippet: 2-Nitroethanol (2ne), 2-nitro-1-propanol (2nprop), 3-nitro-2-pentanol (3n2pent) [mixture of (±) threo and (±) erythro], dextran T500, NaH2 PO4 , Na2 HPO4 , penicillin (5000 U/mL)/streptomycin (5000 μ g/mL), and ethylenediaminetetraacetic acid (EDTA) were obtained from Sigma Chemical (St. Louis, MO).

Techniques: