19-1400 Search Results


coa derivatives palmitoyl coa  (Larodan)
93
Larodan coa derivatives palmitoyl coa
Substrate specificity of Mycobacterium hassiacum OctT towards A) acyl donor B) acceptor substrate C) acyl donors with oligosaccharides mimicking specific acylated motifs found in mature MGLP structure.
Coa Derivatives Palmitoyl Coa, supplied by Larodan, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/coa derivatives palmitoyl coa/product/Larodan
Average 93 stars, based on 1 article reviews
coa derivatives palmitoyl coa - by Bioz Stars, 2025-11
93/100 stars
  Buy from Supplier

Image Search Results


Substrate specificity of Mycobacterium hassiacum OctT towards A) acyl donor B) acceptor substrate C) acyl donors with oligosaccharides mimicking specific acylated motifs found in mature MGLP structure.

Journal: Scientific Reports

Article Title: Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides

doi: 10.1038/srep13610

Figure Lengend Snippet: Substrate specificity of Mycobacterium hassiacum OctT towards A) acyl donor B) acceptor substrate C) acyl donors with oligosaccharides mimicking specific acylated motifs found in mature MGLP structure.

Article Snippet: The CoA derivatives palmitoyl-CoA (C16), tetradecanoyl-CoA (C14), dodecanoyl-CoA (C12), decanoyl-CoA (C10), octanoyl-CoA (C8, Oct-CoA), hexanoyl-CoA (C6, Hex-CoA), succinyl-CoA, butyryl-CoA (C4), propionyl-CoA (C3) and acetyl-CoA (C2) (last three from Larodan Fine Chemicals) were tested as possible acyl donors.

Techniques:

DGG was incubated individually with acyl-CoAs including C2 (a), C3 (b), C4 (c), C6 (d), C8 (e), C10 (f), C12 (g) C14 (h) and C16 (i) in addition to succinyl-CoA (j) in the presence of OctT from M. hassiacum . Mass spectra from reactions where transferase activity was observed are colored red while spectra lacking product are colored blue. In all cases except for C14 the spectra from control reactions lacked the observed product peaks. A peak at the expected size of the C14 reaction product was observed in both control reactions and the C12 spectra. Its presence in those spectra and the lack of product in the C12 and C16 reactions makes it unlikely that this ion represents an authentic DGG-C14 reaction product. Spectra were normalized and analyzed using the open-source mMass software package and all identified masses are the [M-H] −1 ions.

Journal: Scientific Reports

Article Title: Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides

doi: 10.1038/srep13610

Figure Lengend Snippet: DGG was incubated individually with acyl-CoAs including C2 (a), C3 (b), C4 (c), C6 (d), C8 (e), C10 (f), C12 (g) C14 (h) and C16 (i) in addition to succinyl-CoA (j) in the presence of OctT from M. hassiacum . Mass spectra from reactions where transferase activity was observed are colored red while spectra lacking product are colored blue. In all cases except for C14 the spectra from control reactions lacked the observed product peaks. A peak at the expected size of the C14 reaction product was observed in both control reactions and the C12 spectra. Its presence in those spectra and the lack of product in the C12 and C16 reactions makes it unlikely that this ion represents an authentic DGG-C14 reaction product. Spectra were normalized and analyzed using the open-source mMass software package and all identified masses are the [M-H] −1 ions.

Article Snippet: The CoA derivatives palmitoyl-CoA (C16), tetradecanoyl-CoA (C14), dodecanoyl-CoA (C12), decanoyl-CoA (C10), octanoyl-CoA (C8, Oct-CoA), hexanoyl-CoA (C6, Hex-CoA), succinyl-CoA, butyryl-CoA (C4), propionyl-CoA (C3) and acetyl-CoA (C2) (last three from Larodan Fine Chemicals) were tested as possible acyl donors.

Techniques: Incubation, Activity Assay, Software