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vcap cell line  (ATCC)


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    ATCC vcap cell line
    Vcap Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1270 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/vcap+cells/VCaP/pm42265380-92-0-6
    Average 97 stars, based on 1270 article reviews
    vcap cell line - by Bioz Stars, 2026-10
    97/100 stars

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    other:

    Article Title: Drugging the intrinsically disordered transactivation domain of androgen receptor
    Article Snippet: LNCaP cells were obtained from Dr. Lelund Chung (Cedars Sinai Medical Center, Los Angeles, CA), LNCaP95 cells from Dr. Jun Luo (Johns Hopkins University, Baltimore, MD) and PC3 and VCaP cells were obtained from American Type Culture Collection (Manassas, VA).

    Multiple Displacement Amplification:

    Article Title: Landscape of allele-specific expression in prostate cancer reveals recurrent, stage-specific events in AR signaling and resistance pathways
    Article Snippet: Correspondence to Franklin W. Huang. franklin.huang@ucsf.edu; Mailing Address: 513 Parnassus Avenue, S1457C, San Francisco, CA 94143.. Author contributions Conceptualization: M.T., J.L., and F.W.H.. ; Data curation and acquisition: M.T., K.H., D.A.Q.

    Article Title: A Novel Drug Candidate that Selectively Targets the Critical Androgen Receptor-ELK1 Growth Axis in Advanced and Drug-Resistant Prostate Cancer
    Article Snippet: .. 22Rv1 cells, LNCaP cells, VCaP cells, DU145 cells, A549 cells, MDA-231 cells and HeLa cells were purchased from ATCC and frozen after less than 5 passages. ..

    Cell Culture:

    Article Title: Landscape of allele-specific expression in prostate cancer reveals recurrent, stage-specific events in AR signaling and resistance pathways
    Article Snippet: Correspondence to Franklin W. Huang. franklin.huang@ucsf.edu; Mailing Address: 513 Parnassus Avenue, S1457C, San Francisco, CA 94143.. Author contributions Conceptualization: M.T., J.L., and F.W.H.. ; Data curation and acquisition: M.T., K.H., D.A.Q.

    Article Title: AURKA inhibitor VIC-1911 induces mitotic defects and functional BRCAness, sensitizing prostate cancer to PARP inhibition.
    Article Snippet: LNCaP, C4-2B, 22Rv1, DU145, PC3 cells were cultured in RPMI 1640 (Gibco) (with 10% fetal bovine serum (FBS) and 1% penn/strep. .. VCaP cells were cultured in DMEM (ATCC) with 10% FBS and 1% penicillin/streptomycin. .. LAPC4 were cultured in 10% FBS, 1% Pen/strep in IMDM (Gibco).

    Article Title: Single-cell imaging analysis, therapeutic modeling and a Phase Ib trial validate BCL-2 as a target across heterogeneous castration-resistant prostate cancer
    Article Snippet: .. LNCaP, LAPC4 and VCaP cells were purchased from the American Type Culture Collection (ATCC) and cultured in RPMI-1640 medium (for LNCaP) or DMEM (for LAPC4 and VCaP) plus 10% heat-inactivated fetal bovine serum (FBS) and antibiotics. ..

    Article Title: Effect of TGF-β mediated phenotypic changes on prostate cancer cell anoikis response
    Article Snippet: These cells were maintained in RPMI medium (10-040CM) from Corning, NY, supplemented with 10% Fetal Bovine Serum and 1% Penicillin-Streptomycin from Thermo Fisher Scientific, MA, in an incubator (37 °C, 5% CO 2 ). .. VCaP cells (androgen-sensitive; TGF-β responsive) (ATCC CRL-2876) (RRID:CVCL_2235) were cultured in Dulbecco’s Modified Eagle’s Medium containing 4500 mg/L glucose (30-2002) from ATCC, Manassas, VA supplemented with 10% Fetal Bovine Serum and 1% Penicillin-Streptomycin. ..

    Modification:

    Article Title: Effect of TGF-β mediated phenotypic changes on prostate cancer cell anoikis response
    Article Snippet: These cells were maintained in RPMI medium (10-040CM) from Corning, NY, supplemented with 10% Fetal Bovine Serum and 1% Penicillin-Streptomycin from Thermo Fisher Scientific, MA, in an incubator (37 °C, 5% CO 2 ). .. VCaP cells (androgen-sensitive; TGF-β responsive) (ATCC CRL-2876) (RRID:CVCL_2235) were cultured in Dulbecco’s Modified Eagle’s Medium containing 4500 mg/L glucose (30-2002) from ATCC, Manassas, VA supplemented with 10% Fetal Bovine Serum and 1% Penicillin-Streptomycin. ..



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    Panels A-I: Viability of VCaP cells, LNCaP cells or CWR22Rv1-AR-EK cells was determined at the indicated time points of treatment with vehicle or three concentrations of the enzalutamide, KCI807 or KCI838, as indicated, using a standard MTT assay conducted as described under Methods and values were plotted as percent of the Day 0 values. For statistical analysis, the treatment curves were compared in each case with the corresponding vehicle control as described under Methods. Panels J-M: Viability of the AR-negative DU145 cells, MDA-MB-231 cells, HeLa cells and MDA-MB-231 cells was determined at the end of four days of treatment with vehicle and two concentrations of KCI838, as indicated, using a standard MTT assay conducted as described under Methods and values were plotted as percent of the Day 0 values, considering the Day 0 values to be 100 percent. Statistical analysis of the histograms, conducted as described under Methods, did not show significant effects of the compounds.

    Journal: bioRxiv

    Article Title: A Novel Drug Candidate that Selectively Targets the Critical Androgen Receptor-ELK1 Growth Axis in Advanced and Drug-Resistant Prostate Cancer

    doi: 10.64898/2026.05.26.727474

    Figure Lengend Snippet: Panels A-I: Viability of VCaP cells, LNCaP cells or CWR22Rv1-AR-EK cells was determined at the indicated time points of treatment with vehicle or three concentrations of the enzalutamide, KCI807 or KCI838, as indicated, using a standard MTT assay conducted as described under Methods and values were plotted as percent of the Day 0 values. For statistical analysis, the treatment curves were compared in each case with the corresponding vehicle control as described under Methods. Panels J-M: Viability of the AR-negative DU145 cells, MDA-MB-231 cells, HeLa cells and MDA-MB-231 cells was determined at the end of four days of treatment with vehicle and two concentrations of KCI838, as indicated, using a standard MTT assay conducted as described under Methods and values were plotted as percent of the Day 0 values, considering the Day 0 values to be 100 percent. Statistical analysis of the histograms, conducted as described under Methods, did not show significant effects of the compounds.

    Article Snippet: 22Rv1 cells, LNCaP cells, VCaP cells, DU145 cells, A549 cells, MDA-231 cells and HeLa cells were purchased from ATCC and frozen after less than 5 passages.

    Techniques: MTT Assay, Control