Structured Review

5 PRIME utr
PCA of gene features grouped by <t>MSL</t> binding and expression status . Results of PCA of gene feature sequences of genes that are expressed/unexpressed and strongly/weakly bound by MSL. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; O = all genes, Δ = expressed genes (EXP), ∇ = unexpressed genes (UN-EXP), + = MSL strongly bound genes (MSL-SB), × = MSL weakly bound genes (MSL-WB), Δ = expressed MSL strongly bound genes (EXP-MSL-SB), ∇ = expressed MSL weakly bound genes (EXP-MSL-WB). (A) , (B) , (C) , (D) , (E) and (F) show 1 st vs 2 nd component score plots (R2cum = 0.657, 0.517, 0.732, 0.872, 0.577 and 0.761, respectively) of the AT-normalized 2-6 mer promoter, 5' <t>UTR,</t> coding sequence, intron, 3' UTR and intergenic sequence analyses, respectively.
Utr, supplied by 5 PRIME, used in various techniques. Bioz Stars score: 92/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/utr/product/5 PRIME
Average 92 stars, based on 5 article reviews
Price from $9.99 to $1999.99
utr - by Bioz Stars, 2020-08
92/100 stars

Images

1) Product Images from "Sequence signatures involved in targeting the male-specific lethal complex to X-chromosomal genes in Drosophila melanogaster"

Article Title: Sequence signatures involved in targeting the male-specific lethal complex to X-chromosomal genes in Drosophila melanogaster

Journal: BMC Genomics

doi: 10.1186/1471-2164-13-97

PCA of gene features grouped by MSL binding and expression status . Results of PCA of gene feature sequences of genes that are expressed/unexpressed and strongly/weakly bound by MSL. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; O = all genes, Δ = expressed genes (EXP), ∇ = unexpressed genes (UN-EXP), + = MSL strongly bound genes (MSL-SB), × = MSL weakly bound genes (MSL-WB), Δ = expressed MSL strongly bound genes (EXP-MSL-SB), ∇ = expressed MSL weakly bound genes (EXP-MSL-WB). (A) , (B) , (C) , (D) , (E) and (F) show 1 st vs 2 nd component score plots (R2cum = 0.657, 0.517, 0.732, 0.872, 0.577 and 0.761, respectively) of the AT-normalized 2-6 mer promoter, 5' UTR, coding sequence, intron, 3' UTR and intergenic sequence analyses, respectively.
Figure Legend Snippet: PCA of gene features grouped by MSL binding and expression status . Results of PCA of gene feature sequences of genes that are expressed/unexpressed and strongly/weakly bound by MSL. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; O = all genes, Δ = expressed genes (EXP), ∇ = unexpressed genes (UN-EXP), + = MSL strongly bound genes (MSL-SB), × = MSL weakly bound genes (MSL-WB), Δ = expressed MSL strongly bound genes (EXP-MSL-SB), ∇ = expressed MSL weakly bound genes (EXP-MSL-WB). (A) , (B) , (C) , (D) , (E) and (F) show 1 st vs 2 nd component score plots (R2cum = 0.657, 0.517, 0.732, 0.872, 0.577 and 0.761, respectively) of the AT-normalized 2-6 mer promoter, 5' UTR, coding sequence, intron, 3' UTR and intergenic sequence analyses, respectively.

Techniques Used: Binding Assay, Expressing, Western Blot, Sequencing

PCA of D. melanogaster gene features . Results of PCA of frequencies of sequence words within gene features in Dm chromosome arms. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; ∇ = promoter, Δ = 5'UTR, □ = CDS, O = intron, + = 3'UTR, × = intergenic. (A) Scatter plot of PCA first component scores of the gene features versus their AT contents. (B), (C) and (D): 1 st vs 2 nd , 3 rd vs 4 th and 5 th vs 6 th component score plots (R2cum = 0.774, 0.923 and 0.954, respectively) of the AT-normalized analysis of 2-6 mer frequencies in gene features.
Figure Legend Snippet: PCA of D. melanogaster gene features . Results of PCA of frequencies of sequence words within gene features in Dm chromosome arms. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; ∇ = promoter, Δ = 5'UTR, □ = CDS, O = intron, + = 3'UTR, × = intergenic. (A) Scatter plot of PCA first component scores of the gene features versus their AT contents. (B), (C) and (D): 1 st vs 2 nd , 3 rd vs 4 th and 5 th vs 6 th component score plots (R2cum = 0.774, 0.923 and 0.954, respectively) of the AT-normalized analysis of 2-6 mer frequencies in gene features.

Techniques Used: Sequencing

2) Product Images from "Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs"

Article Title: Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs

Journal: Frontiers in Molecular Biosciences

doi: 10.3389/fmolb.2018.00027

(A) Distribution of RNA binding proteins sites from (A) Clipdb-PARalyzer, (B) starBase, and (C) doRiNA datasets across protein coding genes. X-axis of the graph depicts the RBP sites in protein coding genes and Y-axis is the percentage of mapping of these binding sites across the 5′UTR, CDS, and 3′ UTR.
Figure Legend Snippet: (A) Distribution of RNA binding proteins sites from (A) Clipdb-PARalyzer, (B) starBase, and (C) doRiNA datasets across protein coding genes. X-axis of the graph depicts the RBP sites in protein coding genes and Y-axis is the percentage of mapping of these binding sites across the 5′UTR, CDS, and 3′ UTR.

Techniques Used: RNA Binding Assay, Binding Assay

3) Product Images from "Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs"

Article Title: Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs

Journal: Frontiers in Molecular Biosciences

doi: 10.3389/fmolb.2018.00027

(A) Distribution of RNA binding proteins sites from (A) Clipdb-PARalyzer, (B) starBase, and (C) doRiNA datasets across protein coding genes. X-axis of the graph depicts the RBP sites in protein coding genes and Y-axis is the percentage of mapping of these binding sites across the 5′UTR, CDS, and 3′ UTR.
Figure Legend Snippet: (A) Distribution of RNA binding proteins sites from (A) Clipdb-PARalyzer, (B) starBase, and (C) doRiNA datasets across protein coding genes. X-axis of the graph depicts the RBP sites in protein coding genes and Y-axis is the percentage of mapping of these binding sites across the 5′UTR, CDS, and 3′ UTR.

Techniques Used: RNA Binding Assay, Binding Assay

4) Product Images from "Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs"

Article Title: Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs

Journal: Frontiers in Molecular Biosciences

doi: 10.3389/fmolb.2018.00027

(A) Distribution of RNA binding proteins sites from (A) Clipdb-PARalyzer, (B) starBase, and (C) doRiNA datasets across protein coding genes. X-axis of the graph depicts the RBP sites in protein coding genes and Y-axis is the percentage of mapping of these binding sites across the 5′UTR, CDS, and 3′ UTR.
Figure Legend Snippet: (A) Distribution of RNA binding proteins sites from (A) Clipdb-PARalyzer, (B) starBase, and (C) doRiNA datasets across protein coding genes. X-axis of the graph depicts the RBP sites in protein coding genes and Y-axis is the percentage of mapping of these binding sites across the 5′UTR, CDS, and 3′ UTR.

Techniques Used: RNA Binding Assay, Binding Assay

5) Product Images from "Sequence signatures involved in targeting the male-specific lethal complex to X-chromosomal genes in Drosophila melanogaster"

Article Title: Sequence signatures involved in targeting the male-specific lethal complex to X-chromosomal genes in Drosophila melanogaster

Journal: BMC Genomics

doi: 10.1186/1471-2164-13-97

PCA of gene features grouped by MSL binding and expression status . Results of PCA of gene feature sequences of genes that are expressed/unexpressed and strongly/weakly bound by MSL. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; O = all genes, Δ = expressed genes (EXP), ∇ = unexpressed genes (UN-EXP), + = MSL strongly bound genes (MSL-SB), × = MSL weakly bound genes (MSL-WB), Δ = expressed MSL strongly bound genes (EXP-MSL-SB), ∇ = expressed MSL weakly bound genes (EXP-MSL-WB). (A) , (B) , (C) , (D) , (E) and (F) show 1 st vs 2 nd component score plots (R2cum = 0.657, 0.517, 0.732, 0.872, 0.577 and 0.761, respectively) of the AT-normalized 2-6 mer promoter, 5' UTR, coding sequence, intron, 3' UTR and intergenic sequence analyses, respectively.
Figure Legend Snippet: PCA of gene features grouped by MSL binding and expression status . Results of PCA of gene feature sequences of genes that are expressed/unexpressed and strongly/weakly bound by MSL. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; O = all genes, Δ = expressed genes (EXP), ∇ = unexpressed genes (UN-EXP), + = MSL strongly bound genes (MSL-SB), × = MSL weakly bound genes (MSL-WB), Δ = expressed MSL strongly bound genes (EXP-MSL-SB), ∇ = expressed MSL weakly bound genes (EXP-MSL-WB). (A) , (B) , (C) , (D) , (E) and (F) show 1 st vs 2 nd component score plots (R2cum = 0.657, 0.517, 0.732, 0.872, 0.577 and 0.761, respectively) of the AT-normalized 2-6 mer promoter, 5' UTR, coding sequence, intron, 3' UTR and intergenic sequence analyses, respectively.

Techniques Used: Binding Assay, Expressing, Western Blot, Sequencing

PCA of D. melanogaster gene features . Results of PCA of frequencies of sequence words within gene features in Dm chromosome arms. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; ∇ = promoter, Δ = 5'UTR, □ = CDS, O = intron, + = 3'UTR, × = intergenic. (A) Scatter plot of PCA first component scores of the gene features versus their AT contents. (B), (C) and (D): 1 st vs 2 nd , 3 rd vs 4 th and 5 th vs 6 th component score plots (R2cum = 0.774, 0.923 and 0.954, respectively) of the AT-normalized analysis of 2-6 mer frequencies in gene features.
Figure Legend Snippet: PCA of D. melanogaster gene features . Results of PCA of frequencies of sequence words within gene features in Dm chromosome arms. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; ∇ = promoter, Δ = 5'UTR, □ = CDS, O = intron, + = 3'UTR, × = intergenic. (A) Scatter plot of PCA first component scores of the gene features versus their AT contents. (B), (C) and (D): 1 st vs 2 nd , 3 rd vs 4 th and 5 th vs 6 th component score plots (R2cum = 0.774, 0.923 and 0.954, respectively) of the AT-normalized analysis of 2-6 mer frequencies in gene features.

Techniques Used: Sequencing

6) Product Images from "Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs"

Article Title: Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs

Journal: Frontiers in Molecular Biosciences

doi: 10.3389/fmolb.2018.00027

(A) Distribution of RNA binding proteins sites from (A) Clipdb-PARalyzer, (B) starBase, and (C) doRiNA datasets across protein coding genes. X-axis of the graph depicts the RBP sites in protein coding genes and Y-axis is the percentage of mapping of these binding sites across the 5′UTR, CDS, and 3′ UTR.
Figure Legend Snippet: (A) Distribution of RNA binding proteins sites from (A) Clipdb-PARalyzer, (B) starBase, and (C) doRiNA datasets across protein coding genes. X-axis of the graph depicts the RBP sites in protein coding genes and Y-axis is the percentage of mapping of these binding sites across the 5′UTR, CDS, and 3′ UTR.

Techniques Used: RNA Binding Assay, Binding Assay

Related Articles

Sequencing:

Article Title: Sequence signatures involved in targeting the male-specific lethal complex to X-chromosomal genes in Drosophila melanogaster
Article Snippet: .. Abbreviations Dm : Drosophila melanogaster ; MSL: Male-specific lethal; CDS: Coding Sequence; 5' UTR: 5 prime untranslated region; 3' UTR: 3 prime untranslated region; TSS: Transcription start site; HAS: High affinity site; PCA: Principal component analysis; OPLS-DA: Orthogonal partial least squares discriminant analysis; PWM: Position weight matrix ..

Functional Assay:

Article Title: Genome-Wide SNPs and InDels Characteristics of Three Chinese Cattle Breeds
Article Snippet: .. The SnpEff functional class vocabulary assigned to both SNPs and InDels were Untranslated Region(UTR) variant include 3 prime UTR and 5 prime UTR, Downstream and upstream gene variant, intergenic region, intragenic, intron, non-coding transcript exon and non-coding transcript variant, splice variant (splice acceptor, splice donor and splice region), start lost, stop gained, stop lost and stop retained. .. Functional classes exclusively used for InDels were conserved in-frame deletion and insertion, disruptive in-frame deletion and insertion, bidirectional gene fusion, frameshift, conservative-disruptive inframe InDel, whereas missense, initiator codon and synonymous were only assigned to SNPs.

Variant Assay:

Article Title: Genome-Wide SNPs and InDels Characteristics of Three Chinese Cattle Breeds
Article Snippet: .. The SnpEff functional class vocabulary assigned to both SNPs and InDels were Untranslated Region(UTR) variant include 3 prime UTR and 5 prime UTR, Downstream and upstream gene variant, intergenic region, intragenic, intron, non-coding transcript exon and non-coding transcript variant, splice variant (splice acceptor, splice donor and splice region), start lost, stop gained, stop lost and stop retained. .. Functional classes exclusively used for InDels were conserved in-frame deletion and insertion, disruptive in-frame deletion and insertion, bidirectional gene fusion, frameshift, conservative-disruptive inframe InDel, whereas missense, initiator codon and synonymous were only assigned to SNPs.

RNA Binding Assay:

Article Title: Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs
Article Snippet: .. We observed that RNA binding protein interaction sites were distributed in 3 prime UTR, 5 prime UTR, and coding exons and frequencies varied for each protein. ..

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  • utr  (5 PRIME)
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    5 PRIME utr
    PCA of gene features grouped by <t>MSL</t> binding and expression status . Results of PCA of gene feature sequences of genes that are expressed/unexpressed and strongly/weakly bound by MSL. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; O = all genes, Δ = expressed genes (EXP), ∇ = unexpressed genes (UN-EXP), + = MSL strongly bound genes (MSL-SB), × = MSL weakly bound genes (MSL-WB), Δ = expressed MSL strongly bound genes (EXP-MSL-SB), ∇ = expressed MSL weakly bound genes (EXP-MSL-WB). (A) , (B) , (C) , (D) , (E) and (F) show 1 st vs 2 nd component score plots (R2cum = 0.657, 0.517, 0.732, 0.872, 0.577 and 0.761, respectively) of the AT-normalized 2-6 mer promoter, 5' <t>UTR,</t> coding sequence, intron, 3' UTR and intergenic sequence analyses, respectively.
    Utr, supplied by 5 PRIME, used in various techniques. Bioz Stars score: 92/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/utr/product/5 PRIME
    Average 92 stars, based on 5 article reviews
    Price from $9.99 to $1999.99
    utr - by Bioz Stars, 2020-08
    92/100 stars
      Buy from Supplier

    86
    5 PRIME 5 prime utr introns
    Intragenic deletion involving a portion of MBD5 <t>intron</t> 4 . A schematic representation of MBD5, depicting the <t>5′-UTR,</t> exons (black boxes), and intronic regions. We depict the .061 Mb intron 4 deletion (in red) in the 5′-noncoding region of MBD5 at chr(2)(q23.1); (chr2.hg19:g.149,036,875-149,098,081).
    5 Prime Utr Introns, supplied by 5 PRIME, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/5 prime utr introns/product/5 PRIME
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    5 prime utr introns - by Bioz Stars, 2020-08
    86/100 stars
      Buy from Supplier

    Image Search Results


    PCA of gene features grouped by MSL binding and expression status . Results of PCA of gene feature sequences of genes that are expressed/unexpressed and strongly/weakly bound by MSL. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; O = all genes, Δ = expressed genes (EXP), ∇ = unexpressed genes (UN-EXP), + = MSL strongly bound genes (MSL-SB), × = MSL weakly bound genes (MSL-WB), Δ = expressed MSL strongly bound genes (EXP-MSL-SB), ∇ = expressed MSL weakly bound genes (EXP-MSL-WB). (A) , (B) , (C) , (D) , (E) and (F) show 1 st vs 2 nd component score plots (R2cum = 0.657, 0.517, 0.732, 0.872, 0.577 and 0.761, respectively) of the AT-normalized 2-6 mer promoter, 5' UTR, coding sequence, intron, 3' UTR and intergenic sequence analyses, respectively.

    Journal: BMC Genomics

    Article Title: Sequence signatures involved in targeting the male-specific lethal complex to X-chromosomal genes in Drosophila melanogaster

    doi: 10.1186/1471-2164-13-97

    Figure Lengend Snippet: PCA of gene features grouped by MSL binding and expression status . Results of PCA of gene feature sequences of genes that are expressed/unexpressed and strongly/weakly bound by MSL. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; O = all genes, Δ = expressed genes (EXP), ∇ = unexpressed genes (UN-EXP), + = MSL strongly bound genes (MSL-SB), × = MSL weakly bound genes (MSL-WB), Δ = expressed MSL strongly bound genes (EXP-MSL-SB), ∇ = expressed MSL weakly bound genes (EXP-MSL-WB). (A) , (B) , (C) , (D) , (E) and (F) show 1 st vs 2 nd component score plots (R2cum = 0.657, 0.517, 0.732, 0.872, 0.577 and 0.761, respectively) of the AT-normalized 2-6 mer promoter, 5' UTR, coding sequence, intron, 3' UTR and intergenic sequence analyses, respectively.

    Article Snippet: Abbreviations Dm : Drosophila melanogaster ; MSL: Male-specific lethal; CDS: Coding Sequence; 5' UTR: 5 prime untranslated region; 3' UTR: 3 prime untranslated region; TSS: Transcription start site; HAS: High affinity site; PCA: Principal component analysis; OPLS-DA: Orthogonal partial least squares discriminant analysis; PWM: Position weight matrix

    Techniques: Binding Assay, Expressing, Western Blot, Sequencing

    PCA of D. melanogaster gene features . Results of PCA of frequencies of sequence words within gene features in Dm chromosome arms. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; ∇ = promoter, Δ = 5'UTR, □ = CDS, O = intron, + = 3'UTR, × = intergenic. (A) Scatter plot of PCA first component scores of the gene features versus their AT contents. (B), (C) and (D): 1 st vs 2 nd , 3 rd vs 4 th and 5 th vs 6 th component score plots (R2cum = 0.774, 0.923 and 0.954, respectively) of the AT-normalized analysis of 2-6 mer frequencies in gene features.

    Journal: BMC Genomics

    Article Title: Sequence signatures involved in targeting the male-specific lethal complex to X-chromosomal genes in Drosophila melanogaster

    doi: 10.1186/1471-2164-13-97

    Figure Lengend Snippet: PCA of D. melanogaster gene features . Results of PCA of frequencies of sequence words within gene features in Dm chromosome arms. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; ∇ = promoter, Δ = 5'UTR, □ = CDS, O = intron, + = 3'UTR, × = intergenic. (A) Scatter plot of PCA first component scores of the gene features versus their AT contents. (B), (C) and (D): 1 st vs 2 nd , 3 rd vs 4 th and 5 th vs 6 th component score plots (R2cum = 0.774, 0.923 and 0.954, respectively) of the AT-normalized analysis of 2-6 mer frequencies in gene features.

    Article Snippet: Abbreviations Dm : Drosophila melanogaster ; MSL: Male-specific lethal; CDS: Coding Sequence; 5' UTR: 5 prime untranslated region; 3' UTR: 3 prime untranslated region; TSS: Transcription start site; HAS: High affinity site; PCA: Principal component analysis; OPLS-DA: Orthogonal partial least squares discriminant analysis; PWM: Position weight matrix

    Techniques: Sequencing

    (A) Distribution of RNA binding proteins sites from (A) Clipdb-PARalyzer, (B) starBase, and (C) doRiNA datasets across protein coding genes. X-axis of the graph depicts the RBP sites in protein coding genes and Y-axis is the percentage of mapping of these binding sites across the 5′UTR, CDS, and 3′ UTR.

    Journal: Frontiers in Molecular Biosciences

    Article Title: Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs

    doi: 10.3389/fmolb.2018.00027

    Figure Lengend Snippet: (A) Distribution of RNA binding proteins sites from (A) Clipdb-PARalyzer, (B) starBase, and (C) doRiNA datasets across protein coding genes. X-axis of the graph depicts the RBP sites in protein coding genes and Y-axis is the percentage of mapping of these binding sites across the 5′UTR, CDS, and 3′ UTR.

    Article Snippet: We observed that RNA binding protein interaction sites were distributed in 3 prime UTR, 5 prime UTR, and coding exons and frequencies varied for each protein.

    Techniques: RNA Binding Assay, Binding Assay

    (A) Distribution of RNA binding proteins sites from (A) Clipdb-PARalyzer, (B) starBase, and (C) doRiNA datasets across protein coding genes. X-axis of the graph depicts the RBP sites in protein coding genes and Y-axis is the percentage of mapping of these binding sites across the 5′UTR, CDS, and 3′ UTR.

    Journal: Frontiers in Molecular Biosciences

    Article Title: Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs

    doi: 10.3389/fmolb.2018.00027

    Figure Lengend Snippet: (A) Distribution of RNA binding proteins sites from (A) Clipdb-PARalyzer, (B) starBase, and (C) doRiNA datasets across protein coding genes. X-axis of the graph depicts the RBP sites in protein coding genes and Y-axis is the percentage of mapping of these binding sites across the 5′UTR, CDS, and 3′ UTR.

    Article Snippet: We observed that RNA binding protein interaction sites were distributed in 3 prime UTR, 5 prime UTR, and coding exons and frequencies varied for each protein.

    Techniques: RNA Binding Assay, Binding Assay

    Intragenic deletion involving a portion of MBD5 intron 4 . A schematic representation of MBD5, depicting the 5′-UTR, exons (black boxes), and intronic regions. We depict the .061 Mb intron 4 deletion (in red) in the 5′-noncoding region of MBD5 at chr(2)(q23.1); (chr2.hg19:g.149,036,875-149,098,081).

    Journal: Molecular Cytogenetics

    Article Title: Intragenic MBD5 familial deletion variant does not negatively impact MBD5 mRNA expression

    doi: 10.1186/s13039-014-0080-9

    Figure Lengend Snippet: Intragenic deletion involving a portion of MBD5 intron 4 . A schematic representation of MBD5, depicting the 5′-UTR, exons (black boxes), and intronic regions. We depict the .061 Mb intron 4 deletion (in red) in the 5′-noncoding region of MBD5 at chr(2)(q23.1); (chr2.hg19:g.149,036,875-149,098,081).

    Article Snippet: Further, deletions in 5-prime UTR introns could lead to altered expression if transcription factor binding is affected.

    Techniques: