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GeneTex twf1
miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or <t>TWF1</t> siRNA. *p
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Images

1) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

2) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

3) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

4) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

5) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

6) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

7) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

8) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

9) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

10) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

11) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

12) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

13) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

14) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

15) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

16) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

17) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

18) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

19) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

20) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

21) Product Images from "MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11"

Article Title: MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11

Journal: Nature communications

doi: 10.1038/ncomms2393

IL-11 as a downstream target of TWF1
Figure Legend Snippet: IL-11 as a downstream target of TWF1

Techniques Used:

miR-30c regulates EMT and directly targets TWF1
Figure Legend Snippet: miR-30c regulates EMT and directly targets TWF1

Techniques Used:

TWF1 is required for miR-30c functions
Figure Legend Snippet: TWF1 is required for miR-30c functions

Techniques Used:

22) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

23) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

24) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

25) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

26) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

27) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

28) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

29) Product Images from "MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway"

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-16-0943

miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p
Figure Legend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

Techniques Used: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection

Related Articles

Reverse Transcription Polymerase Chain Reaction:

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway
Article Snippet: .. RT-PCR results also demonstrated that in MCF7 cells miR-206 overexpression led to a comparable reduction of TWF1, MKL1, and IL-11 expression levels and signaling from TWF1 to MKL1 and IL-11 as in other breast cancer cells ( ). ..

other:

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway
Article Snippet: These findings show IL-11 is an important downstream target of miR-206 and TWF1 in regulating breast cancer invasion and metastasis.

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway
Article Snippet: Bockhorn J, Dalton R, Nwachukwu C, Huang S, Prat A, Yee K, et al. MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11.

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway
Article Snippet: These data indicate that TWF1 is an important and direct target of miR-206 in regulating breast cancer cell invasion.

Migration:

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway
Article Snippet: .. We also observed that both miR-206 upregulation and IL-11 knockdown reduced the CD44 expression that is a marker of cancer stem cells in breast cancer ( ) Overall our data report a novel signaling pathway mediated by miR-206 that targets TWF1, MKL1 and SRF, and subsequently IL-11 expression, thereby inhibiting cell cycle and self-renewal in tumorigenesis as well as cell motility (EMT, migration, invadopodia formation, and invasion) in breast cancer metastasis ( ). .. High levels of miR-206 reduce TWF1 expression that not only causes high free G-actin to trap MKL1 in the cytoplasm and reduce its transcriptional activity along with SRF, but also reduces its expression levels.

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway
Article Snippet: .. Knockdown of TWF1 also mimicked miR-206 upregulation in decreasing cell motility (migration) of MCF-7 cells ( ). .. However, the downstream signaling of TWF1 was not fully understood, and we decided to seek out mesenchymal regulators related to miR-206/TWF1 functions.

Expressing:

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway
Article Snippet: .. Forced expression of miR-206 caused a significant decrease in mRNA levels for NOTCH2, G6PD, and TWF1 compared to the scrambled control (Scr) ( ). ..

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway
Article Snippet: .. RT-PCR results also demonstrated that in MCF7 cells miR-206 overexpression led to a comparable reduction of TWF1, MKL1, and IL-11 expression levels and signaling from TWF1 to MKL1 and IL-11 as in other breast cancer cells ( ). ..

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway
Article Snippet: .. We also observed that both miR-206 upregulation and IL-11 knockdown reduced the CD44 expression that is a marker of cancer stem cells in breast cancer ( ) Overall our data report a novel signaling pathway mediated by miR-206 that targets TWF1, MKL1 and SRF, and subsequently IL-11 expression, thereby inhibiting cell cycle and self-renewal in tumorigenesis as well as cell motility (EMT, migration, invadopodia formation, and invasion) in breast cancer metastasis ( ). .. High levels of miR-206 reduce TWF1 expression that not only causes high free G-actin to trap MKL1 in the cytoplasm and reduce its transcriptional activity along with SRF, but also reduces its expression levels.

Marker:

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway
Article Snippet: .. We also observed that both miR-206 upregulation and IL-11 knockdown reduced the CD44 expression that is a marker of cancer stem cells in breast cancer ( ) Overall our data report a novel signaling pathway mediated by miR-206 that targets TWF1, MKL1 and SRF, and subsequently IL-11 expression, thereby inhibiting cell cycle and self-renewal in tumorigenesis as well as cell motility (EMT, migration, invadopodia formation, and invasion) in breast cancer metastasis ( ). .. High levels of miR-206 reduce TWF1 expression that not only causes high free G-actin to trap MKL1 in the cytoplasm and reduce its transcriptional activity along with SRF, but also reduces its expression levels.

Over Expression:

Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway
Article Snippet: .. RT-PCR results also demonstrated that in MCF7 cells miR-206 overexpression led to a comparable reduction of TWF1, MKL1, and IL-11 expression levels and signaling from TWF1 to MKL1 and IL-11 as in other breast cancer cells ( ). ..

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    GeneTex twf1
    miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or <t>TWF1</t> siRNA. *p
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    miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

    Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

    Article Title: MicroRNA-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway

    doi: 10.1158/1078-0432.CCR-16-0943

    Figure Lengend Snippet: miR-206 decreases invasion through regulating MKL1/SRF and IL-11 A. Realtime PCR of MKL1 expression in MDA-MB-231 cells transfected with either scramble, miR-206 or TWF1 siRNA. *p

    Article Snippet: Knockdown of TWF1 also mimicked miR-206 upregulation in decreasing cell motility (migration) of MCF-7 cells ( ).

    Techniques: Polymerase Chain Reaction, Expressing, Multiple Displacement Amplification, Transfection