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tnc shrna lentiviral particle  (Santa Cruz Biotechnology)

 
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    Santa Cruz Biotechnology tnc shrna lentiviral particle
    Tnc Shrna Lentiviral Particle, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tnc shrna lentiviral particle/product/Santa Cruz Biotechnology
    Average 88 stars, based on 1 article reviews
    tnc shrna lentiviral particle - by Bioz Stars, 2025-06
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    Knocking-down of <t>TNC</t> expression blunts MET-mediated stromal activation. ( a ) TNC-specific qRT-PCR analysis of mRNA derived from HPAF-II cells (wild-type or genetically engineered to express <t>TNC-shRNAs)</t> treated with HGF. Data are expressed as fold-change values relative to the untreated control (wild-type HPAF-II). ( b ) α-SMA-specific qRT-PCR analysis of mRNA derived from human PSCs co-cultured with HPAF-II wild-type or genetically engineered to express TNC-shRNAs, treated with MvDN30 and decoyMET K842E in combination (Combo). Data are expressed as fold-change values relative to untreated control (PSCs co-cultured with wild-type HPAF-II). NT, untreated controls. Each bar represents the average value ± SD. Student’s t test: *, p ≤ 0.05; **, p ≤ 0.01; ***, p ≤ 0.001; ns, not significant. Data reported in figure are representative of at least two independent experiments.
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    tnc shrna lentiviral particle  (Santa Cruz Biotechnology)
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    Santa Cruz Biotechnology tnc shrna lentiviral particle
    Knocking-down of <t>TNC</t> expression blunts MET-mediated stromal activation. ( a ) TNC-specific qRT-PCR analysis of mRNA derived from HPAF-II cells (wild-type or genetically engineered to express <t>TNC-shRNAs)</t> treated with HGF. Data are expressed as fold-change values relative to the untreated control (wild-type HPAF-II). ( b ) α-SMA-specific qRT-PCR analysis of mRNA derived from human PSCs co-cultured with HPAF-II wild-type or genetically engineered to express TNC-shRNAs, treated with MvDN30 and decoyMET K842E in combination (Combo). Data are expressed as fold-change values relative to untreated control (PSCs co-cultured with wild-type HPAF-II). NT, untreated controls. Each bar represents the average value ± SD. Student’s t test: *, p ≤ 0.05; **, p ≤ 0.01; ***, p ≤ 0.001; ns, not significant. Data reported in figure are representative of at least two independent experiments.
    Tnc Shrna Lentiviral Particle, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 88 stars, based on 1 article reviews
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    tnc shrna lentiviral particles  (Santa Cruz Biotechnology)
    88
    Santa Cruz Biotechnology tnc shrna lentiviral particles
    Knocking-down of <t>TNC</t> expression blunts MET-mediated stromal activation. ( a ) TNC-specific qRT-PCR analysis of mRNA derived from HPAF-II cells (wild-type or genetically engineered to express <t>TNC-shRNAs)</t> treated with HGF. Data are expressed as fold-change values relative to the untreated control (wild-type HPAF-II). ( b ) α-SMA-specific qRT-PCR analysis of mRNA derived from human PSCs co-cultured with HPAF-II wild-type or genetically engineered to express TNC-shRNAs, treated with MvDN30 and decoyMET K842E in combination (Combo). Data are expressed as fold-change values relative to untreated control (PSCs co-cultured with wild-type HPAF-II). NT, untreated controls. Each bar represents the average value ± SD. Student’s t test: *, p ≤ 0.05; **, p ≤ 0.01; ***, p ≤ 0.001; ns, not significant. Data reported in figure are representative of at least two independent experiments.
    Tnc Shrna Lentiviral Particles, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tnc shrna lentiviral particles/product/Santa Cruz Biotechnology
    Average 88 stars, based on 1 article reviews
    tnc shrna lentiviral particles - by Bioz Stars, 2025-06
    88/100 stars
    		  Buy from Supplier

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    Knocking-down of TNC expression blunts MET-mediated stromal activation. ( a ) TNC-specific qRT-PCR analysis of mRNA derived from HPAF-II cells (wild-type or genetically engineered to express TNC-shRNAs) treated with HGF. Data are expressed as fold-change values relative to the untreated control (wild-type HPAF-II). ( b ) α-SMA-specific qRT-PCR analysis of mRNA derived from human PSCs co-cultured with HPAF-II wild-type or genetically engineered to express TNC-shRNAs, treated with MvDN30 and decoyMET K842E in combination (Combo). Data are expressed as fold-change values relative to untreated control (PSCs co-cultured with wild-type HPAF-II). NT, untreated controls. Each bar represents the average value ± SD. Student’s t test: *, p ≤ 0.05; **, p ≤ 0.01; ***, p ≤ 0.001; ns, not significant. Data reported in figure are representative of at least two independent experiments.

    Journal: Cancers

    Article Title: HGF/MET Axis Induces Tumor Secretion of Tenascin-C and Promotes Stromal Rewiring in Pancreatic Cancer

    doi: 10.3390/cancers13143519

    Figure Lengend Snippet: Knocking-down of TNC expression blunts MET-mediated stromal activation. ( a ) TNC-specific qRT-PCR analysis of mRNA derived from HPAF-II cells (wild-type or genetically engineered to express TNC-shRNAs) treated with HGF. Data are expressed as fold-change values relative to the untreated control (wild-type HPAF-II). ( b ) α-SMA-specific qRT-PCR analysis of mRNA derived from human PSCs co-cultured with HPAF-II wild-type or genetically engineered to express TNC-shRNAs, treated with MvDN30 and decoyMET K842E in combination (Combo). Data are expressed as fold-change values relative to untreated control (PSCs co-cultured with wild-type HPAF-II). NT, untreated controls. Each bar represents the average value ± SD. Student’s t test: *, p ≤ 0.05; **, p ≤ 0.01; ***, p ≤ 0.001; ns, not significant. Data reported in figure are representative of at least two independent experiments.

    Article Snippet: HPAF-II cells were plated in 6-well costar dishes (10 5 cells/well) and infected for 24 h with lentiviral vector particles expressing TNC shRNAs (NM_002160 from Sigma Aldrich, St. Louis, MO, USA) in the presence of 8 μg/mL polybrene.

    Techniques: Expressing, Activation Assay, Quantitative RT-PCR, Derivative Assay, Cell Culture