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tlr 4  (Proteintech)


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    Proteintech tlr 4
    Tlr 4, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1142 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tlr 4/product/Proteintech
    Average 96 stars, based on 1142 article reviews
    tlr 4 - by Bioz Stars, 2026-06
    96/100 stars

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    Inhibitory effect of MKE on the TLR4-NFκB signaling pathway. The expression levels of <t>TLR-4,</t> p-IκBα/IκBα, and p-p65/p65 in tissues collected at week 16 were evaluated. ( A ) Representative Western blot image. ( B ) Quantitative analysis of TLR-4 expression. ( C ) Quantitative analysis of the p-IκBα/IκBα expression ratio. ( D ) Quantitative analysis of the p-p65/p65 ratio. The data are expressed as mean ± standard deviation ( n = 3/group). * p < 0.05, ** p < 0.01 compared to the ligature control group; # p < 0.05 versus the non-ligature control group. Non-ligature = non-ligature control group, Ligature = ligature control group, Doxycycline = ligature + doxycycline 20 mg/kg group, MKE 100 = ligature + MKE 100 mg/kg group, MKE 400 = ligature + MKE 400 mg/kg group.
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    Inhibitory effect of MKE on the TLR4-NFκB signaling pathway. The expression levels of TLR-4, p-IκBα/IκBα, and p-p65/p65 in tissues collected at week 16 were evaluated. ( A ) Representative Western blot image. ( B ) Quantitative analysis of TLR-4 expression. ( C ) Quantitative analysis of the p-IκBα/IκBα expression ratio. ( D ) Quantitative analysis of the p-p65/p65 ratio. The data are expressed as mean ± standard deviation ( n = 3/group). * p < 0.05, ** p < 0.01 compared to the ligature control group; # p < 0.05 versus the non-ligature control group. Non-ligature = non-ligature control group, Ligature = ligature control group, Doxycycline = ligature + doxycycline 20 mg/kg group, MKE 100 = ligature + MKE 100 mg/kg group, MKE 400 = ligature + MKE 400 mg/kg group.

    Journal: Current Issues in Molecular Biology

    Article Title: Protective Effects of Magnolia kobus DC. Extract on Inflammatory Response and Alveolar Bone Loss in Ligature-Induced Periodontitis Rats

    doi: 10.3390/cimb48010109

    Figure Lengend Snippet: Inhibitory effect of MKE on the TLR4-NFκB signaling pathway. The expression levels of TLR-4, p-IκBα/IκBα, and p-p65/p65 in tissues collected at week 16 were evaluated. ( A ) Representative Western blot image. ( B ) Quantitative analysis of TLR-4 expression. ( C ) Quantitative analysis of the p-IκBα/IκBα expression ratio. ( D ) Quantitative analysis of the p-p65/p65 ratio. The data are expressed as mean ± standard deviation ( n = 3/group). * p < 0.05, ** p < 0.01 compared to the ligature control group; # p < 0.05 versus the non-ligature control group. Non-ligature = non-ligature control group, Ligature = ligature control group, Doxycycline = ligature + doxycycline 20 mg/kg group, MKE 100 = ligature + MKE 100 mg/kg group, MKE 400 = ligature + MKE 400 mg/kg group.

    Article Snippet: Toll-like receptor 4 (TLR-4) , Cell Signaling Technology (Danvers, MA, USA).

    Techniques: Expressing, Western Blot, Standard Deviation, Control

    The postulated mechanism underlying the anti-periodontitis activity of MKE. MKE = Magnolia kobus DC. extract, ROS = reactive oxygen species, TLR-4 = toll-like receptor 4, p-IκBα = phosphorylated inhibitor of κBα, IκBα = inhibitor of κBα, IL-1β = interleukin-1β, IL-6 = interleukin-6, TNF-α = tumor necrosis factor-α, COX-2 = cyclooxygenase-2, MMPs = matrix metalloproteinases.

    Journal: Current Issues in Molecular Biology

    Article Title: Protective Effects of Magnolia kobus DC. Extract on Inflammatory Response and Alveolar Bone Loss in Ligature-Induced Periodontitis Rats

    doi: 10.3390/cimb48010109

    Figure Lengend Snippet: The postulated mechanism underlying the anti-periodontitis activity of MKE. MKE = Magnolia kobus DC. extract, ROS = reactive oxygen species, TLR-4 = toll-like receptor 4, p-IκBα = phosphorylated inhibitor of κBα, IκBα = inhibitor of κBα, IL-1β = interleukin-1β, IL-6 = interleukin-6, TNF-α = tumor necrosis factor-α, COX-2 = cyclooxygenase-2, MMPs = matrix metalloproteinases.

    Article Snippet: Toll-like receptor 4 (TLR-4) , Cell Signaling Technology (Danvers, MA, USA).

    Techniques: Activity Assay