phospho p44 42 mapk erk1 2 thr202 tyr204 antibody  (Cell Signaling Technology Inc)


Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 86

    Structured Review

    Cell Signaling Technology Inc phospho p44 42 mapk erk1 2 thr202 tyr204 antibody
    Phospho P44 42 Mapk Erk1 2 Thr202 Tyr204 Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phospho p44 42 mapk erk1 2 thr202 tyr204 antibody/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    phospho p44 42 mapk erk1 2 thr202 tyr204 antibody - by Bioz Stars, 2024-06
    86/100 stars

    Images

    rabbit monoclonal anti phospho erk1 2 thr202 tyr204 antibody  (Cell Signaling Technology Inc)


    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 86

    Structured Review

    Cell Signaling Technology Inc rabbit monoclonal anti phospho erk1 2 thr202 tyr204 antibody
    Rabbit Monoclonal Anti Phospho Erk1 2 Thr202 Tyr204 Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit monoclonal anti phospho erk1 2 thr202 tyr204 antibody/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit monoclonal anti phospho erk1 2 thr202 tyr204 antibody - by Bioz Stars, 2024-06
    86/100 stars

    Images

    anti phospho erk1 2 thr202 tyr204  (Cell Signaling Technology Inc)


    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 86

    Structured Review

    Cell Signaling Technology Inc anti phospho erk1 2 thr202 tyr204
    HOXB2 modulates the expression of ABC transporters and Erk activity. A . Functional analysis of the differentially expressed genes from the RNA-Seq results of OV8 shNC cells and sh HOXB2 cells based on KEGG pathways. B . Relative mRNA levels of ABC transporters in OV8 shNC and sh HOXB2 cells. C . Gene set enrichment analysis was performed to compare the OV8 shNC and sh HOXB2 cells. NES, Normalized enrichment score. D . qPCR results showing the expression levels of ABC transporters of shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. E . Correlation analysis of HOXB2 with ABCA1 , ABCC3 , and ABCG1 based on the TCGA database. r, Pearson’s correlation coefficient. F . WB analysis of ABCA1 and ABCG1 expression in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. G . GSEA result of OV8 shNC cells and sh HOXB2 cells. H . WB results of <t>p-MAPK42/44</t> <t>(Erk1/2)</t> and total Erk levels in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. * P < 0.05, ** P < 0.01, *** P < 0.001, *** P < 0.0001
    Anti Phospho Erk1 2 Thr202 Tyr204, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti phospho erk1 2 thr202 tyr204/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti phospho erk1 2 thr202 tyr204 - by Bioz Stars, 2024-06
    86/100 stars

    Images

    1) Product Images from "HOXB2 promotes cisplatin resistance by upregulating lncRNA DANCR in ovarian cancer"

    Article Title: HOXB2 promotes cisplatin resistance by upregulating lncRNA DANCR in ovarian cancer

    Journal: Journal of Ovarian Research

    doi: 10.1186/s13048-024-01424-1

    HOXB2 modulates the expression of ABC transporters and Erk activity. A . Functional analysis of the differentially expressed genes from the RNA-Seq results of OV8 shNC cells and sh HOXB2 cells based on KEGG pathways. B . Relative mRNA levels of ABC transporters in OV8 shNC and sh HOXB2 cells. C . Gene set enrichment analysis was performed to compare the OV8 shNC and sh HOXB2 cells. NES, Normalized enrichment score. D . qPCR results showing the expression levels of ABC transporters of shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. E . Correlation analysis of HOXB2 with ABCA1 , ABCC3 , and ABCG1 based on the TCGA database. r, Pearson’s correlation coefficient. F . WB analysis of ABCA1 and ABCG1 expression in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. G . GSEA result of OV8 shNC cells and sh HOXB2 cells. H . WB results of p-MAPK42/44 (Erk1/2) and total Erk levels in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. * P < 0.05, ** P < 0.01, *** P < 0.001, *** P < 0.0001
    Figure Legend Snippet: HOXB2 modulates the expression of ABC transporters and Erk activity. A . Functional analysis of the differentially expressed genes from the RNA-Seq results of OV8 shNC cells and sh HOXB2 cells based on KEGG pathways. B . Relative mRNA levels of ABC transporters in OV8 shNC and sh HOXB2 cells. C . Gene set enrichment analysis was performed to compare the OV8 shNC and sh HOXB2 cells. NES, Normalized enrichment score. D . qPCR results showing the expression levels of ABC transporters of shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. E . Correlation analysis of HOXB2 with ABCA1 , ABCC3 , and ABCG1 based on the TCGA database. r, Pearson’s correlation coefficient. F . WB analysis of ABCA1 and ABCG1 expression in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. G . GSEA result of OV8 shNC cells and sh HOXB2 cells. H . WB results of p-MAPK42/44 (Erk1/2) and total Erk levels in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. * P < 0.05, ** P < 0.01, *** P < 0.001, *** P < 0.0001

    Techniques Used: Expressing, Activity Assay, Functional Assay, RNA Sequencing Assay

    rabbit anti phospho p44 42 mapk thr202 tyr204  (Cell Signaling Technology Inc)


    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 86

    Structured Review

    Cell Signaling Technology Inc rabbit anti phospho p44 42 mapk thr202 tyr204
    Rabbit Anti Phospho P44 42 Mapk Thr202 Tyr204, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti phospho p44 42 mapk thr202 tyr204/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti phospho p44 42 mapk thr202 tyr204 - by Bioz Stars, 2024-06
    86/100 stars

    Images

    antibodies against phospho thr202 tyr204 p42 p44 mapk  (Cell Signaling Technology Inc)


    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 86

    Structured Review

    Cell Signaling Technology Inc antibodies against phospho thr202 tyr204 p42 p44 mapk
    Antibodies Against Phospho Thr202 Tyr204 P42 P44 Mapk, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/antibodies against phospho thr202 tyr204 p42 p44 mapk/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    antibodies against phospho thr202 tyr204 p42 p44 mapk - by Bioz Stars, 2024-06
    86/100 stars

    Images

    phospho erk1 2 thr202 tyr204  (Cell Signaling Technology Inc)


    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 86

    Structured Review

    Cell Signaling Technology Inc phospho erk1 2 thr202 tyr204
    Phospho Erk1 2 Thr202 Tyr204, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phospho erk1 2 thr202 tyr204/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    phospho erk1 2 thr202 tyr204 - by Bioz Stars, 2024-06
    86/100 stars

    Images

    phospho erk1 2 thr202 tyr204  (Cell Signaling Technology Inc)


    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 86

    Structured Review

    Cell Signaling Technology Inc phospho erk1 2 thr202 tyr204
    Differential protein expression in HUVEC treated with the EVOO extract. Volcano plots show deregulated proteins in conditioned media (A) or cell extracts (B) from HUVEC after treatment with the EVOO extract compared to the control condition. Proteins were considered upregulated (red square) or downregulated (green square) if fold-change values were >2 (Log 2 Ratio >1, red circles) or <0.5 (Log 2 Ratio <1, green circles), respectively. Among these proteins, changes in those with a ρ-value <0.01 were considered significant and grouped in red and green squares. Significantly deregulated proteins are labeled in each case. Gray circles, not significant. (C) Western-blot analysis of EFEMP1, CCN2, <t>and</t> <t>ERK1/2</t> and its phosphorylated form was performed. Relative quantification (fold change) of the protein levels of EFEMP1 (D), CCN2 (E), and phosphorylated-ERK1/2 (F) was done. Means ± SD of a minimum of three independent experiments are shown, and Student’s t test was performed for the statistical analysis (* p < 0.05, ** p < 0.01).
    Phospho Erk1 2 Thr202 Tyr204, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phospho erk1 2 thr202 tyr204/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    phospho erk1 2 thr202 tyr204 - by Bioz Stars, 2024-06
    86/100 stars

    Images

    1) Product Images from "Antiangiogenic Potential of an Olive Oil Extract: Insights from a Proteomic Study"

    Article Title: Antiangiogenic Potential of an Olive Oil Extract: Insights from a Proteomic Study

    Journal: Journal of Agricultural and Food Chemistry

    doi: 10.1021/acs.jafc.3c08851

    Differential protein expression in HUVEC treated with the EVOO extract. Volcano plots show deregulated proteins in conditioned media (A) or cell extracts (B) from HUVEC after treatment with the EVOO extract compared to the control condition. Proteins were considered upregulated (red square) or downregulated (green square) if fold-change values were >2 (Log 2 Ratio >1, red circles) or <0.5 (Log 2 Ratio <1, green circles), respectively. Among these proteins, changes in those with a ρ-value <0.01 were considered significant and grouped in red and green squares. Significantly deregulated proteins are labeled in each case. Gray circles, not significant. (C) Western-blot analysis of EFEMP1, CCN2, and ERK1/2 and its phosphorylated form was performed. Relative quantification (fold change) of the protein levels of EFEMP1 (D), CCN2 (E), and phosphorylated-ERK1/2 (F) was done. Means ± SD of a minimum of three independent experiments are shown, and Student’s t test was performed for the statistical analysis (* p < 0.05, ** p < 0.01).
    Figure Legend Snippet: Differential protein expression in HUVEC treated with the EVOO extract. Volcano plots show deregulated proteins in conditioned media (A) or cell extracts (B) from HUVEC after treatment with the EVOO extract compared to the control condition. Proteins were considered upregulated (red square) or downregulated (green square) if fold-change values were >2 (Log 2 Ratio >1, red circles) or <0.5 (Log 2 Ratio <1, green circles), respectively. Among these proteins, changes in those with a ρ-value <0.01 were considered significant and grouped in red and green squares. Significantly deregulated proteins are labeled in each case. Gray circles, not significant. (C) Western-blot analysis of EFEMP1, CCN2, and ERK1/2 and its phosphorylated form was performed. Relative quantification (fold change) of the protein levels of EFEMP1 (D), CCN2 (E), and phosphorylated-ERK1/2 (F) was done. Means ± SD of a minimum of three independent experiments are shown, and Student’s t test was performed for the statistical analysis (* p < 0.05, ** p < 0.01).

    Techniques Used: Expressing, Control, Labeling, Western Blot

    AKT phosphorylation is severely hampered in endothelial cells following EVOO treatment. (A) Representative blots of total AKT and ERK 1/2 proteins and their phosphorylated forms in BAEC extracts. Tubulin was used as an internal loading control. Similar results were obtained in, at least, three independent experiments. Refer to Figure S5 for the unedited version of this blot. (B, C) Densitometric quantification of the blots (fold change in ERK1/2 activation). Means ± SD of a minimum of three independent experiments are shown. One-way ANOVA plus Dunnett’s multiple comparison tests were performed for the statistical analysis (* p < 0.05; ** p < 0.01).
    Figure Legend Snippet: AKT phosphorylation is severely hampered in endothelial cells following EVOO treatment. (A) Representative blots of total AKT and ERK 1/2 proteins and their phosphorylated forms in BAEC extracts. Tubulin was used as an internal loading control. Similar results were obtained in, at least, three independent experiments. Refer to Figure S5 for the unedited version of this blot. (B, C) Densitometric quantification of the blots (fold change in ERK1/2 activation). Means ± SD of a minimum of three independent experiments are shown. One-way ANOVA plus Dunnett’s multiple comparison tests were performed for the statistical analysis (* p < 0.05; ** p < 0.01).

    Techniques Used: Control, Activation Assay, Comparison

    phospho erk thr202 tyr204  (Cell Signaling Technology Inc)


    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 86

    Structured Review

    Cell Signaling Technology Inc phospho erk thr202 tyr204
    Phospho Erk Thr202 Tyr204, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phospho erk thr202 tyr204/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    phospho erk thr202 tyr204 - by Bioz Stars, 2024-06
    86/100 stars

    Images

    anti phospho erk1 2 thr202 tyr204  (Cell Signaling Technology Inc)


    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 86

    Structured Review

    Cell Signaling Technology Inc anti phospho erk1 2 thr202 tyr204
    Anti Phospho Erk1 2 Thr202 Tyr204, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti phospho erk1 2 thr202 tyr204/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti phospho erk1 2 thr202 tyr204 - by Bioz Stars, 2024-06
    86/100 stars

    Images

    anti phospho p44 42 mapk erk1 2 thr202 tyr204 rabbit mab  (Cell Signaling Technology Inc)


    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 86

    Structured Review

    Cell Signaling Technology Inc anti phospho p44 42 mapk erk1 2 thr202 tyr204 rabbit mab
    A: Immunoblot analysis of MAPK and PI3K/AKT signaling in the presence of increasing doses of erdafitinib, growth factors- In untreated <t>fibroblasts,</t> <t>ERK1/2</t> and AKT (both pAKT-T308 and pAKT-S473) are activated (in NC, normal control (no DMSO), 0 nM erdafitinib but with DMSO), Erdafitinib treatment at 100 nM dramatically reduce activated pERK1/2 and pAKT with no further reductions detected when fibroblasts were treated with 200 nM or 300 nM erdafitinib (3A-a) . Erdafitinib-inhibited pERK1/2 was not re-activated by the co-addition of IGF-I ( 3A-b ), FGF2 ( 3A-c ) or IGF-2 ( 3A-d ). AKT signaling pathway (pAKT-T308 and pAKT-S473) were consistently activated by IGF-I and IGF-2, but not by FGF2 ( 3A ), at all concentrations of erdafitinib tested (100 nM–300 nM) (see -uncropped.) .B: immunoblot analysis of signaling response in the presence of erdafitinib and growth factors over time- Fibroblasts were co-treated with 200nM erdafitinib and growth factors (IGF-1, IGF-2, FGF-2) for 0.5, 2, 24, 48 hours. Only with IGF-I treatment, activation of AKT was sustained for 48 hours. our data suggest, in our patient fibroblasts, that IGF-I activation of AKT signaling is sustained and independent of the FGFR signaling inhibitory effects of erdafitinib. (see -uncropped.).
    Anti Phospho P44 42 Mapk Erk1 2 Thr202 Tyr204 Rabbit Mab, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti phospho p44 42 mapk erk1 2 thr202 tyr204 rabbit mab/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti phospho p44 42 mapk erk1 2 thr202 tyr204 rabbit mab - by Bioz Stars, 2024-06
    86/100 stars

    Images

    1) Product Images from "Skeletal overgrowth in a pre-pubescent child treated with pan-FGFR inhibitor"

    Article Title: Skeletal overgrowth in a pre-pubescent child treated with pan-FGFR inhibitor

    Journal: Heliyon

    doi: 10.1016/j.heliyon.2024.e30887

    A: Immunoblot analysis of MAPK and PI3K/AKT signaling in the presence of increasing doses of erdafitinib, growth factors- In untreated fibroblasts, ERK1/2 and AKT (both pAKT-T308 and pAKT-S473) are activated (in NC, normal control (no DMSO), 0 nM erdafitinib but with DMSO), Erdafitinib treatment at 100 nM dramatically reduce activated pERK1/2 and pAKT with no further reductions detected when fibroblasts were treated with 200 nM or 300 nM erdafitinib (3A-a) . Erdafitinib-inhibited pERK1/2 was not re-activated by the co-addition of IGF-I ( 3A-b ), FGF2 ( 3A-c ) or IGF-2 ( 3A-d ). AKT signaling pathway (pAKT-T308 and pAKT-S473) were consistently activated by IGF-I and IGF-2, but not by FGF2 ( 3A ), at all concentrations of erdafitinib tested (100 nM–300 nM) (see -uncropped.) .B: immunoblot analysis of signaling response in the presence of erdafitinib and growth factors over time- Fibroblasts were co-treated with 200nM erdafitinib and growth factors (IGF-1, IGF-2, FGF-2) for 0.5, 2, 24, 48 hours. Only with IGF-I treatment, activation of AKT was sustained for 48 hours. our data suggest, in our patient fibroblasts, that IGF-I activation of AKT signaling is sustained and independent of the FGFR signaling inhibitory effects of erdafitinib. (see -uncropped.).
    Figure Legend Snippet: A: Immunoblot analysis of MAPK and PI3K/AKT signaling in the presence of increasing doses of erdafitinib, growth factors- In untreated fibroblasts, ERK1/2 and AKT (both pAKT-T308 and pAKT-S473) are activated (in NC, normal control (no DMSO), 0 nM erdafitinib but with DMSO), Erdafitinib treatment at 100 nM dramatically reduce activated pERK1/2 and pAKT with no further reductions detected when fibroblasts were treated with 200 nM or 300 nM erdafitinib (3A-a) . Erdafitinib-inhibited pERK1/2 was not re-activated by the co-addition of IGF-I ( 3A-b ), FGF2 ( 3A-c ) or IGF-2 ( 3A-d ). AKT signaling pathway (pAKT-T308 and pAKT-S473) were consistently activated by IGF-I and IGF-2, but not by FGF2 ( 3A ), at all concentrations of erdafitinib tested (100 nM–300 nM) (see -uncropped.) .B: immunoblot analysis of signaling response in the presence of erdafitinib and growth factors over time- Fibroblasts were co-treated with 200nM erdafitinib and growth factors (IGF-1, IGF-2, FGF-2) for 0.5, 2, 24, 48 hours. Only with IGF-I treatment, activation of AKT was sustained for 48 hours. our data suggest, in our patient fibroblasts, that IGF-I activation of AKT signaling is sustained and independent of the FGFR signaling inhibitory effects of erdafitinib. (see -uncropped.).

    Techniques Used: Western Blot, Activation Assay

    Similar Products

  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 86
    Cell Signaling Technology Inc phospho p44 42 mapk erk1 2 thr202 tyr204 antibody
    Phospho P44 42 Mapk Erk1 2 Thr202 Tyr204 Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phospho p44 42 mapk erk1 2 thr202 tyr204 antibody/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    phospho p44 42 mapk erk1 2 thr202 tyr204 antibody - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    86
    Cell Signaling Technology Inc rabbit monoclonal anti phospho erk1 2 thr202 tyr204 antibody
    Rabbit Monoclonal Anti Phospho Erk1 2 Thr202 Tyr204 Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit monoclonal anti phospho erk1 2 thr202 tyr204 antibody/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit monoclonal anti phospho erk1 2 thr202 tyr204 antibody - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    86
    Cell Signaling Technology Inc anti phospho erk1 2 thr202 tyr204
    HOXB2 modulates the expression of ABC transporters and Erk activity. A . Functional analysis of the differentially expressed genes from the RNA-Seq results of OV8 shNC cells and sh HOXB2 cells based on KEGG pathways. B . Relative mRNA levels of ABC transporters in OV8 shNC and sh HOXB2 cells. C . Gene set enrichment analysis was performed to compare the OV8 shNC and sh HOXB2 cells. NES, Normalized enrichment score. D . qPCR results showing the expression levels of ABC transporters of shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. E . Correlation analysis of HOXB2 with ABCA1 , ABCC3 , and ABCG1 based on the TCGA database. r, Pearson’s correlation coefficient. F . WB analysis of ABCA1 and ABCG1 expression in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. G . GSEA result of OV8 shNC cells and sh HOXB2 cells. H . WB results of <t>p-MAPK42/44</t> <t>(Erk1/2)</t> and total Erk levels in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. * P < 0.05, ** P < 0.01, *** P < 0.001, *** P < 0.0001
    Anti Phospho Erk1 2 Thr202 Tyr204, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti phospho erk1 2 thr202 tyr204/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti phospho erk1 2 thr202 tyr204 - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    86
    Cell Signaling Technology Inc rabbit anti phospho p44 42 mapk thr202 tyr204
    HOXB2 modulates the expression of ABC transporters and Erk activity. A . Functional analysis of the differentially expressed genes from the RNA-Seq results of OV8 shNC cells and sh HOXB2 cells based on KEGG pathways. B . Relative mRNA levels of ABC transporters in OV8 shNC and sh HOXB2 cells. C . Gene set enrichment analysis was performed to compare the OV8 shNC and sh HOXB2 cells. NES, Normalized enrichment score. D . qPCR results showing the expression levels of ABC transporters of shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. E . Correlation analysis of HOXB2 with ABCA1 , ABCC3 , and ABCG1 based on the TCGA database. r, Pearson’s correlation coefficient. F . WB analysis of ABCA1 and ABCG1 expression in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. G . GSEA result of OV8 shNC cells and sh HOXB2 cells. H . WB results of <t>p-MAPK42/44</t> <t>(Erk1/2)</t> and total Erk levels in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. * P < 0.05, ** P < 0.01, *** P < 0.001, *** P < 0.0001
    Rabbit Anti Phospho P44 42 Mapk Thr202 Tyr204, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti phospho p44 42 mapk thr202 tyr204/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti phospho p44 42 mapk thr202 tyr204 - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    86
    Cell Signaling Technology Inc antibodies against phospho thr202 tyr204 p42 p44 mapk
    HOXB2 modulates the expression of ABC transporters and Erk activity. A . Functional analysis of the differentially expressed genes from the RNA-Seq results of OV8 shNC cells and sh HOXB2 cells based on KEGG pathways. B . Relative mRNA levels of ABC transporters in OV8 shNC and sh HOXB2 cells. C . Gene set enrichment analysis was performed to compare the OV8 shNC and sh HOXB2 cells. NES, Normalized enrichment score. D . qPCR results showing the expression levels of ABC transporters of shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. E . Correlation analysis of HOXB2 with ABCA1 , ABCC3 , and ABCG1 based on the TCGA database. r, Pearson’s correlation coefficient. F . WB analysis of ABCA1 and ABCG1 expression in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. G . GSEA result of OV8 shNC cells and sh HOXB2 cells. H . WB results of <t>p-MAPK42/44</t> <t>(Erk1/2)</t> and total Erk levels in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. * P < 0.05, ** P < 0.01, *** P < 0.001, *** P < 0.0001
    Antibodies Against Phospho Thr202 Tyr204 P42 P44 Mapk, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/antibodies against phospho thr202 tyr204 p42 p44 mapk/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    antibodies against phospho thr202 tyr204 p42 p44 mapk - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    86
    Cell Signaling Technology Inc phospho erk1 2 thr202 tyr204
    HOXB2 modulates the expression of ABC transporters and Erk activity. A . Functional analysis of the differentially expressed genes from the RNA-Seq results of OV8 shNC cells and sh HOXB2 cells based on KEGG pathways. B . Relative mRNA levels of ABC transporters in OV8 shNC and sh HOXB2 cells. C . Gene set enrichment analysis was performed to compare the OV8 shNC and sh HOXB2 cells. NES, Normalized enrichment score. D . qPCR results showing the expression levels of ABC transporters of shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. E . Correlation analysis of HOXB2 with ABCA1 , ABCC3 , and ABCG1 based on the TCGA database. r, Pearson’s correlation coefficient. F . WB analysis of ABCA1 and ABCG1 expression in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. G . GSEA result of OV8 shNC cells and sh HOXB2 cells. H . WB results of <t>p-MAPK42/44</t> <t>(Erk1/2)</t> and total Erk levels in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. * P < 0.05, ** P < 0.01, *** P < 0.001, *** P < 0.0001
    Phospho Erk1 2 Thr202 Tyr204, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phospho erk1 2 thr202 tyr204/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    phospho erk1 2 thr202 tyr204 - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    86
    Cell Signaling Technology Inc phospho erk thr202 tyr204
    HOXB2 modulates the expression of ABC transporters and Erk activity. A . Functional analysis of the differentially expressed genes from the RNA-Seq results of OV8 shNC cells and sh HOXB2 cells based on KEGG pathways. B . Relative mRNA levels of ABC transporters in OV8 shNC and sh HOXB2 cells. C . Gene set enrichment analysis was performed to compare the OV8 shNC and sh HOXB2 cells. NES, Normalized enrichment score. D . qPCR results showing the expression levels of ABC transporters of shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. E . Correlation analysis of HOXB2 with ABCA1 , ABCC3 , and ABCG1 based on the TCGA database. r, Pearson’s correlation coefficient. F . WB analysis of ABCA1 and ABCG1 expression in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. G . GSEA result of OV8 shNC cells and sh HOXB2 cells. H . WB results of <t>p-MAPK42/44</t> <t>(Erk1/2)</t> and total Erk levels in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. * P < 0.05, ** P < 0.01, *** P < 0.001, *** P < 0.0001
    Phospho Erk Thr202 Tyr204, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phospho erk thr202 tyr204/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    phospho erk thr202 tyr204 - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    86
    Cell Signaling Technology Inc anti phospho p44 42 mapk erk1 2 thr202 tyr204 rabbit mab
    A: Immunoblot analysis of MAPK and PI3K/AKT signaling in the presence of increasing doses of erdafitinib, growth factors- In untreated <t>fibroblasts,</t> <t>ERK1/2</t> and AKT (both pAKT-T308 and pAKT-S473) are activated (in NC, normal control (no DMSO), 0 nM erdafitinib but with DMSO), Erdafitinib treatment at 100 nM dramatically reduce activated pERK1/2 and pAKT with no further reductions detected when fibroblasts were treated with 200 nM or 300 nM erdafitinib (3A-a) . Erdafitinib-inhibited pERK1/2 was not re-activated by the co-addition of IGF-I ( 3A-b ), FGF2 ( 3A-c ) or IGF-2 ( 3A-d ). AKT signaling pathway (pAKT-T308 and pAKT-S473) were consistently activated by IGF-I and IGF-2, but not by FGF2 ( 3A ), at all concentrations of erdafitinib tested (100 nM–300 nM) (see -uncropped.) .B: immunoblot analysis of signaling response in the presence of erdafitinib and growth factors over time- Fibroblasts were co-treated with 200nM erdafitinib and growth factors (IGF-1, IGF-2, FGF-2) for 0.5, 2, 24, 48 hours. Only with IGF-I treatment, activation of AKT was sustained for 48 hours. our data suggest, in our patient fibroblasts, that IGF-I activation of AKT signaling is sustained and independent of the FGFR signaling inhibitory effects of erdafitinib. (see -uncropped.).
    Anti Phospho P44 42 Mapk Erk1 2 Thr202 Tyr204 Rabbit Mab, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti phospho p44 42 mapk erk1 2 thr202 tyr204 rabbit mab/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti phospho p44 42 mapk erk1 2 thr202 tyr204 rabbit mab - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    Image Search Results


    HOXB2 modulates the expression of ABC transporters and Erk activity. A . Functional analysis of the differentially expressed genes from the RNA-Seq results of OV8 shNC cells and sh HOXB2 cells based on KEGG pathways. B . Relative mRNA levels of ABC transporters in OV8 shNC and sh HOXB2 cells. C . Gene set enrichment analysis was performed to compare the OV8 shNC and sh HOXB2 cells. NES, Normalized enrichment score. D . qPCR results showing the expression levels of ABC transporters of shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. E . Correlation analysis of HOXB2 with ABCA1 , ABCC3 , and ABCG1 based on the TCGA database. r, Pearson’s correlation coefficient. F . WB analysis of ABCA1 and ABCG1 expression in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. G . GSEA result of OV8 shNC cells and sh HOXB2 cells. H . WB results of p-MAPK42/44 (Erk1/2) and total Erk levels in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. * P < 0.05, ** P < 0.01, *** P < 0.001, *** P < 0.0001

    Journal: Journal of Ovarian Research

    Article Title: HOXB2 promotes cisplatin resistance by upregulating lncRNA DANCR in ovarian cancer

    doi: 10.1186/s13048-024-01424-1

    Figure Lengend Snippet: HOXB2 modulates the expression of ABC transporters and Erk activity. A . Functional analysis of the differentially expressed genes from the RNA-Seq results of OV8 shNC cells and sh HOXB2 cells based on KEGG pathways. B . Relative mRNA levels of ABC transporters in OV8 shNC and sh HOXB2 cells. C . Gene set enrichment analysis was performed to compare the OV8 shNC and sh HOXB2 cells. NES, Normalized enrichment score. D . qPCR results showing the expression levels of ABC transporters of shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. E . Correlation analysis of HOXB2 with ABCA1 , ABCC3 , and ABCG1 based on the TCGA database. r, Pearson’s correlation coefficient. F . WB analysis of ABCA1 and ABCG1 expression in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. G . GSEA result of OV8 shNC cells and sh HOXB2 cells. H . WB results of p-MAPK42/44 (Erk1/2) and total Erk levels in shNC, sh HOXB2 -1, and sh HOXB2 -2 cells. * P < 0.05, ** P < 0.01, *** P < 0.001, *** P < 0.0001

    Article Snippet: Antibodies used were as follows: anti-HOXB2 (1:1000, AY2582, Abways), anti-Beta Actin (1:5000, AB0035, Abways), anti-Beta tubulin (1:5000, 10086-1-AP, Proteintech), anti-γH2A.X (1:1000, GB111841, Servicebio), anti-Chk2 (1:10000, CY5633, Abways), anti-phospho Chk2 Thr68 (CY8878, Abways), anti-Chk1 (1:1000, 2360, Cell Signaling Technology), anti-phospho Chk1 Ser345 ((1:1000, 2348, Cell Signaling Technology), anti-ABCA1 (1:1000, ab66217, Abcam), anti-ABCG1 (1:1000, 13578-1-AP, Proteintech), anti-phospho Erk1/2 Thr202/Tyr204 (1:2000, 4370, Cell Signaling Technology), and anti-Erk1/2 (1:1000, 4695, Cell Signaling Technology).

    Techniques: Expressing, Activity Assay, Functional Assay, RNA Sequencing Assay

    A: Immunoblot analysis of MAPK and PI3K/AKT signaling in the presence of increasing doses of erdafitinib, growth factors- In untreated fibroblasts, ERK1/2 and AKT (both pAKT-T308 and pAKT-S473) are activated (in NC, normal control (no DMSO), 0 nM erdafitinib but with DMSO), Erdafitinib treatment at 100 nM dramatically reduce activated pERK1/2 and pAKT with no further reductions detected when fibroblasts were treated with 200 nM or 300 nM erdafitinib (3A-a) . Erdafitinib-inhibited pERK1/2 was not re-activated by the co-addition of IGF-I ( 3A-b ), FGF2 ( 3A-c ) or IGF-2 ( 3A-d ). AKT signaling pathway (pAKT-T308 and pAKT-S473) were consistently activated by IGF-I and IGF-2, but not by FGF2 ( 3A ), at all concentrations of erdafitinib tested (100 nM–300 nM) (see -uncropped.) .B: immunoblot analysis of signaling response in the presence of erdafitinib and growth factors over time- Fibroblasts were co-treated with 200nM erdafitinib and growth factors (IGF-1, IGF-2, FGF-2) for 0.5, 2, 24, 48 hours. Only with IGF-I treatment, activation of AKT was sustained for 48 hours. our data suggest, in our patient fibroblasts, that IGF-I activation of AKT signaling is sustained and independent of the FGFR signaling inhibitory effects of erdafitinib. (see -uncropped.).

    Journal: Heliyon

    Article Title: Skeletal overgrowth in a pre-pubescent child treated with pan-FGFR inhibitor

    doi: 10.1016/j.heliyon.2024.e30887

    Figure Lengend Snippet: A: Immunoblot analysis of MAPK and PI3K/AKT signaling in the presence of increasing doses of erdafitinib, growth factors- In untreated fibroblasts, ERK1/2 and AKT (both pAKT-T308 and pAKT-S473) are activated (in NC, normal control (no DMSO), 0 nM erdafitinib but with DMSO), Erdafitinib treatment at 100 nM dramatically reduce activated pERK1/2 and pAKT with no further reductions detected when fibroblasts were treated with 200 nM or 300 nM erdafitinib (3A-a) . Erdafitinib-inhibited pERK1/2 was not re-activated by the co-addition of IGF-I ( 3A-b ), FGF2 ( 3A-c ) or IGF-2 ( 3A-d ). AKT signaling pathway (pAKT-T308 and pAKT-S473) were consistently activated by IGF-I and IGF-2, but not by FGF2 ( 3A ), at all concentrations of erdafitinib tested (100 nM–300 nM) (see -uncropped.) .B: immunoblot analysis of signaling response in the presence of erdafitinib and growth factors over time- Fibroblasts were co-treated with 200nM erdafitinib and growth factors (IGF-1, IGF-2, FGF-2) for 0.5, 2, 24, 48 hours. Only with IGF-I treatment, activation of AKT was sustained for 48 hours. our data suggest, in our patient fibroblasts, that IGF-I activation of AKT signaling is sustained and independent of the FGFR signaling inhibitory effects of erdafitinib. (see -uncropped.).

    Article Snippet: Antibodies used were anti-phospho-AKT(Ser 473), anti-phospho-AKT(Thr308), and anti-Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) rabbit mAb (Cell Signaling Technology, Danvers, MA), anti-Akt (pan) Rabbit mAb, p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb(Cell Signaling Technology, Danvers, MA), anti-PARP rabbit mAb and Cleaved Caspase-3 (Asp175) (5A1E) Rabbit mAb (Cell Signaling Technology, Danvers, MA), anti-alpha tubulin monoclonal horseradish peroxidase conjugate (Cell Signaling Technology, Danvers, MA), Secondary antibodies (horseradish peroxidase-linked anti-rabbit IgG and anti-mouse IgG antibodies) were obtained from Amersham Biosciences (Uppsala, Sweden).

    Techniques: Western Blot, Activation Assay