thle 2 liver epithelial cells (ATCC)
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Thle 2 Liver Epithelial Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 98/100, based on 663 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/thle+2/THLE-2/pm42885052-161-4-8
Average 98 stars, based on 663 article reviews
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In Vitro:Article Title: Development of Type II Glucose Transporter Inhibitors: Phloretin as a GLUT-2 Screening Template from In Silico Modeling to In Vitro Assessment Article Snippet: .. HepG2 (human HCC; ATCC HB-8065; ATCC, Manassas, VA, USA) and Article Title: KCMF1 promotes MASLD progression via K48-linked ubiquitination and degradation of AMPKα. Article Snippet: Background/Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) lacks effective pharmacotherapy.. Although AMP-activated protein kinase (AMPK) is a central metabolic regulator with hepatoprotective effects, the upstream mechanisms governing its degradation in MASLD remain poorly defined.. Here, we identify potassium channel modulatory factor 1 (KCMF1) as a previously unrecognized E3 ubiquitin ligase targeting AMPKα and investigate its role in MASLD pathogenesis. Cell Culture:Article Title: KCMF1 promotes MASLD progression via K48-linked ubiquitination and degradation of AMPKα. Article Snippet: Background/Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) lacks effective pharmacotherapy.. Although AMP-activated protein kinase (AMPK) is a central metabolic regulator with hepatoprotective effects, the upstream mechanisms governing its degradation in MASLD remain poorly defined.. Here, we identify potassium channel modulatory factor 1 (KCMF1) as a previously unrecognized E3 ubiquitin ligase targeting AMPKα and investigate its role in MASLD pathogenesis. Transfection:Article Title: KCMF1 promotes MASLD progression via K48-linked ubiquitination and degradation of AMPKα. Article Snippet: Background/Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) lacks effective pharmacotherapy.. Although AMP-activated protein kinase (AMPK) is a central metabolic regulator with hepatoprotective effects, the upstream mechanisms governing its degradation in MASLD remain poorly defined.. Here, we identify potassium channel modulatory factor 1 (KCMF1) as a previously unrecognized E3 ubiquitin ligase targeting AMPKα and investigate its role in MASLD pathogenesis. other:Article Title: Phospho-JNK agonists show promising effects for the treatment of hepatocellular carcinoma Article Snippet: Vaccines:Article Title: Phytochemical-mediated green synthesis of selenium nanoparticles using Catharanthus roseus and their physicochemical characterization, biological evaluation, and molecular docking analysis Article Snippet: .. |
