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enriched ytterbium oxide  (ISOFLEX)
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ISOFLEX enriched ytterbium oxide
Enriched Ytterbium Oxide, supplied by ISOFLEX, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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iberiotoxin ibtx  (Alomone Labs)
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Alomone Labs iberiotoxin ibtx
Voltage waves in hf NBMNs are blocked by the selective big‐conductance Ca 2+ ‐activated K + (BK) channel blocker <t>iberiotoxin</t> <t>(IbTx).</t> (A) The frequency (left y axis: in bins) and amplitude (right y axis: in dots) of voltage waves evoked by a current step of 500 pA (500 ms duration) are expressed as a function of time in a representative hf NBM exposed to different compounds: IbTx (200 n m ); ZD7288 (ZD; 50 µ m ) or TEA (0.2 m m ). Letters in the graph (a, b, c) represent specific time points where original voltage traces are compared. (B) Original voltage traces recorded in the same cell at specific time points: before (a: black trace), during (b: red trace), or after (c: blue trace) the application of 200 n m IbTx, a selective BK channel blocker. The dotted line indicates the 0 mV level. Scale bars: 200 ms; 100 mV. Upper panel: magnification of original voltage traces. (C) Representative image of immunofluorescence analysis demonstrating that hf NBMNs express KCNMA1 (KCa1.1: α subunit of BK channels: in red; NeuN in green). The adjacent negative control panel shows the red and green channels acquired after omission of the primary antibodies. Scale bar: 20 µm. (D–K) Averaged time courses (mean ± SE) of wave parameters (frequency, amplitude, integral and half width) measured in 4 hf NBMNs exposed to 200 n m IbTx (D–G) or in 4 hf NBMNs exposed to 0.2 m m TEA (H–K).
Iberiotoxin Ibtx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sti/Iberiotoxin/pmc13397815-197-0-5
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57fe  (ISOFLEX)
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ISOFLEX 57fe
Voltage waves in hf NBMNs are blocked by the selective big‐conductance Ca 2+ ‐activated K + (BK) channel blocker <t>iberiotoxin</t> <t>(IbTx).</t> (A) The frequency (left y axis: in bins) and amplitude (right y axis: in dots) of voltage waves evoked by a current step of 500 pA (500 ms duration) are expressed as a function of time in a representative hf NBM exposed to different compounds: IbTx (200 n m ); ZD7288 (ZD; 50 µ m ) or TEA (0.2 m m ). Letters in the graph (a, b, c) represent specific time points where original voltage traces are compared. (B) Original voltage traces recorded in the same cell at specific time points: before (a: black trace), during (b: red trace), or after (c: blue trace) the application of 200 n m IbTx, a selective BK channel blocker. The dotted line indicates the 0 mV level. Scale bars: 200 ms; 100 mV. Upper panel: magnification of original voltage traces. (C) Representative image of immunofluorescence analysis demonstrating that hf NBMNs express KCNMA1 (KCa1.1: α subunit of BK channels: in red; NeuN in green). The adjacent negative control panel shows the red and green channels acquired after omission of the primary antibodies. Scale bar: 20 µm. (D–K) Averaged time courses (mean ± SE) of wave parameters (frequency, amplitude, integral and half width) measured in 4 hf NBMNs exposed to 200 n m IbTx (D–G) or in 4 hf NBMNs exposed to 0.2 m m TEA (H–K).
57fe, supplied by ISOFLEX, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sti/Iron-57/pm42108069-108-1-11
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tissue  (ISOFLEX)
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ISOFLEX tissue
Voltage waves in hf NBMNs are blocked by the selective big‐conductance Ca 2+ ‐activated K + (BK) channel blocker <t>iberiotoxin</t> <t>(IbTx).</t> (A) The frequency (left y axis: in bins) and amplitude (right y axis: in dots) of voltage waves evoked by a current step of 500 pA (500 ms duration) are expressed as a function of time in a representative hf NBM exposed to different compounds: IbTx (200 n m ); ZD7288 (ZD; 50 µ m ) or TEA (0.2 m m ). Letters in the graph (a, b, c) represent specific time points where original voltage traces are compared. (B) Original voltage traces recorded in the same cell at specific time points: before (a: black trace), during (b: red trace), or after (c: blue trace) the application of 200 n m IbTx, a selective BK channel blocker. The dotted line indicates the 0 mV level. Scale bars: 200 ms; 100 mV. Upper panel: magnification of original voltage traces. (C) Representative image of immunofluorescence analysis demonstrating that hf NBMNs express KCNMA1 (KCa1.1: α subunit of BK channels: in red; NeuN in green). The adjacent negative control panel shows the red and green channels acquired after omission of the primary antibodies. Scale bar: 20 µm. (D–K) Averaged time courses (mean ± SE) of wave parameters (frequency, amplitude, integral and half width) measured in 4 hf NBMNs exposed to 200 n m IbTx (D–G) or in 4 hf NBMNs exposed to 0.2 m m TEA (H–K).
Tissue, supplied by ISOFLEX, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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alinity m sti assay  (Abbott Laboratories)
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Abbott Laboratories alinity m sti assay
Voltage waves in hf NBMNs are blocked by the selective big‐conductance Ca 2+ ‐activated K + (BK) channel blocker <t>iberiotoxin</t> <t>(IbTx).</t> (A) The frequency (left y axis: in bins) and amplitude (right y axis: in dots) of voltage waves evoked by a current step of 500 pA (500 ms duration) are expressed as a function of time in a representative hf NBM exposed to different compounds: IbTx (200 n m ); ZD7288 (ZD; 50 µ m ) or TEA (0.2 m m ). Letters in the graph (a, b, c) represent specific time points where original voltage traces are compared. (B) Original voltage traces recorded in the same cell at specific time points: before (a: black trace), during (b: red trace), or after (c: blue trace) the application of 200 n m IbTx, a selective BK channel blocker. The dotted line indicates the 0 mV level. Scale bars: 200 ms; 100 mV. Upper panel: magnification of original voltage traces. (C) Representative image of immunofluorescence analysis demonstrating that hf NBMNs express KCNMA1 (KCa1.1: α subunit of BK channels: in red; NeuN in green). The adjacent negative control panel shows the red and green channels acquired after omission of the primary antibodies. Scale bar: 20 µm. (D–K) Averaged time courses (mean ± SE) of wave parameters (frequency, amplitude, integral and half width) measured in 4 hf NBMNs exposed to 200 n m IbTx (D–G) or in 4 hf NBMNs exposed to 0.2 m m TEA (H–K).
Alinity M Sti Assay, supplied by Abbott Laboratories, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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98mo enriched moo3 powder  (ISOFLEX)
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ISOFLEX 98mo enriched moo3 powder
Voltage waves in hf NBMNs are blocked by the selective big‐conductance Ca 2+ ‐activated K + (BK) channel blocker <t>iberiotoxin</t> <t>(IbTx).</t> (A) The frequency (left y axis: in bins) and amplitude (right y axis: in dots) of voltage waves evoked by a current step of 500 pA (500 ms duration) are expressed as a function of time in a representative hf NBM exposed to different compounds: IbTx (200 n m ); ZD7288 (ZD; 50 µ m ) or TEA (0.2 m m ). Letters in the graph (a, b, c) represent specific time points where original voltage traces are compared. (B) Original voltage traces recorded in the same cell at specific time points: before (a: black trace), during (b: red trace), or after (c: blue trace) the application of 200 n m IbTx, a selective BK channel blocker. The dotted line indicates the 0 mV level. Scale bars: 200 ms; 100 mV. Upper panel: magnification of original voltage traces. (C) Representative image of immunofluorescence analysis demonstrating that hf NBMNs express KCNMA1 (KCa1.1: α subunit of BK channels: in red; NeuN in green). The adjacent negative control panel shows the red and green channels acquired after omission of the primary antibodies. Scale bar: 20 µm. (D–K) Averaged time courses (mean ± SE) of wave parameters (frequency, amplitude, integral and half width) measured in 4 hf NBMNs exposed to 200 n m IbTx (D–G) or in 4 hf NBMNs exposed to 0.2 m m TEA (H–K).
98mo Enriched Moo3 Powder, supplied by ISOFLEX, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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proteases soy bean trypsin inhibitor sti  (Brickell Biotech)
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Brickell Biotech proteases soy bean trypsin inhibitor sti
Voltage waves in hf NBMNs are blocked by the selective big‐conductance Ca 2+ ‐activated K + (BK) channel blocker <t>iberiotoxin</t> <t>(IbTx).</t> (A) The frequency (left y axis: in bins) and amplitude (right y axis: in dots) of voltage waves evoked by a current step of 500 pA (500 ms duration) are expressed as a function of time in a representative hf NBM exposed to different compounds: IbTx (200 n m ); ZD7288 (ZD; 50 µ m ) or TEA (0.2 m m ). Letters in the graph (a, b, c) represent specific time points where original voltage traces are compared. (B) Original voltage traces recorded in the same cell at specific time points: before (a: black trace), during (b: red trace), or after (c: blue trace) the application of 200 n m IbTx, a selective BK channel blocker. The dotted line indicates the 0 mV level. Scale bars: 200 ms; 100 mV. Upper panel: magnification of original voltage traces. (C) Representative image of immunofluorescence analysis demonstrating that hf NBMNs express KCNMA1 (KCa1.1: α subunit of BK channels: in red; NeuN in green). The adjacent negative control panel shows the red and green channels acquired after omission of the primary antibodies. Scale bar: 20 µm. (D–K) Averaged time courses (mean ± SE) of wave parameters (frequency, amplitude, integral and half width) measured in 4 hf NBMNs exposed to 200 n m IbTx (D–G) or in 4 hf NBMNs exposed to 0.2 m m TEA (H–K).
Proteases Soy Bean Trypsin Inhibitor Sti, supplied by Brickell Biotech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hepatitis und sti diagnosen bei ehemals prep nutzenden im wir eine online befragung im rahmen der  (Innov X Systems)
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Voltage waves in hf NBMNs are blocked by the selective big‐conductance Ca 2+ ‐activated K + (BK) channel blocker <t>iberiotoxin</t> <t>(IbTx).</t> (A) The frequency (left y axis: in bins) and amplitude (right y axis: in dots) of voltage waves evoked by a current step of 500 pA (500 ms duration) are expressed as a function of time in a representative hf NBM exposed to different compounds: IbTx (200 n m ); ZD7288 (ZD; 50 µ m ) or TEA (0.2 m m ). Letters in the graph (a, b, c) represent specific time points where original voltage traces are compared. (B) Original voltage traces recorded in the same cell at specific time points: before (a: black trace), during (b: red trace), or after (c: blue trace) the application of 200 n m IbTx, a selective BK channel blocker. The dotted line indicates the 0 mV level. Scale bars: 200 ms; 100 mV. Upper panel: magnification of original voltage traces. (C) Representative image of immunofluorescence analysis demonstrating that hf NBMNs express KCNMA1 (KCa1.1: α subunit of BK channels: in red; NeuN in green). The adjacent negative control panel shows the red and green channels acquired after omission of the primary antibodies. Scale bar: 20 µm. (D–K) Averaged time courses (mean ± SE) of wave parameters (frequency, amplitude, integral and half width) measured in 4 hf NBMNs exposed to 200 n m IbTx (D–G) or in 4 hf NBMNs exposed to 0.2 m m TEA (H–K).
Hepatitis Und Sti Diagnosen Bei Ehemals Prep Nutzenden Im Wir Eine Online Befragung Im Rahmen Der, supplied by Innov X Systems, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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61ni  (ISOFLEX)
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ISOFLEX 61ni
Voltage waves in hf NBMNs are blocked by the selective big‐conductance Ca 2+ ‐activated K + (BK) channel blocker <t>iberiotoxin</t> <t>(IbTx).</t> (A) The frequency (left y axis: in bins) and amplitude (right y axis: in dots) of voltage waves evoked by a current step of 500 pA (500 ms duration) are expressed as a function of time in a representative hf NBM exposed to different compounds: IbTx (200 n m ); ZD7288 (ZD; 50 µ m ) or TEA (0.2 m m ). Letters in the graph (a, b, c) represent specific time points where original voltage traces are compared. (B) Original voltage traces recorded in the same cell at specific time points: before (a: black trace), during (b: red trace), or after (c: blue trace) the application of 200 n m IbTx, a selective BK channel blocker. The dotted line indicates the 0 mV level. Scale bars: 200 ms; 100 mV. Upper panel: magnification of original voltage traces. (C) Representative image of immunofluorescence analysis demonstrating that hf NBMNs express KCNMA1 (KCa1.1: α subunit of BK channels: in red; NeuN in green). The adjacent negative control panel shows the red and green channels acquired after omission of the primary antibodies. Scale bar: 20 µm. (D–K) Averaged time courses (mean ± SE) of wave parameters (frequency, amplitude, integral and half width) measured in 4 hf NBMNs exposed to 200 n m IbTx (D–G) or in 4 hf NBMNs exposed to 0.2 m m TEA (H–K).
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Image Search Results


Voltage waves in hf NBMNs are blocked by the selective big‐conductance Ca 2+ ‐activated K + (BK) channel blocker iberiotoxin (IbTx). (A) The frequency (left y axis: in bins) and amplitude (right y axis: in dots) of voltage waves evoked by a current step of 500 pA (500 ms duration) are expressed as a function of time in a representative hf NBM exposed to different compounds: IbTx (200 n m ); ZD7288 (ZD; 50 µ m ) or TEA (0.2 m m ). Letters in the graph (a, b, c) represent specific time points where original voltage traces are compared. (B) Original voltage traces recorded in the same cell at specific time points: before (a: black trace), during (b: red trace), or after (c: blue trace) the application of 200 n m IbTx, a selective BK channel blocker. The dotted line indicates the 0 mV level. Scale bars: 200 ms; 100 mV. Upper panel: magnification of original voltage traces. (C) Representative image of immunofluorescence analysis demonstrating that hf NBMNs express KCNMA1 (KCa1.1: α subunit of BK channels: in red; NeuN in green). The adjacent negative control panel shows the red and green channels acquired after omission of the primary antibodies. Scale bar: 20 µm. (D–K) Averaged time courses (mean ± SE) of wave parameters (frequency, amplitude, integral and half width) measured in 4 hf NBMNs exposed to 200 n m IbTx (D–G) or in 4 hf NBMNs exposed to 0.2 m m TEA (H–K).

Journal: Advanced Science

Article Title: Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

doi: 10.1002/advs.76767

Figure Lengend Snippet: Voltage waves in hf NBMNs are blocked by the selective big‐conductance Ca 2+ ‐activated K + (BK) channel blocker iberiotoxin (IbTx). (A) The frequency (left y axis: in bins) and amplitude (right y axis: in dots) of voltage waves evoked by a current step of 500 pA (500 ms duration) are expressed as a function of time in a representative hf NBM exposed to different compounds: IbTx (200 n m ); ZD7288 (ZD; 50 µ m ) or TEA (0.2 m m ). Letters in the graph (a, b, c) represent specific time points where original voltage traces are compared. (B) Original voltage traces recorded in the same cell at specific time points: before (a: black trace), during (b: red trace), or after (c: blue trace) the application of 200 n m IbTx, a selective BK channel blocker. The dotted line indicates the 0 mV level. Scale bars: 200 ms; 100 mV. Upper panel: magnification of original voltage traces. (C) Representative image of immunofluorescence analysis demonstrating that hf NBMNs express KCNMA1 (KCa1.1: α subunit of BK channels: in red; NeuN in green). The adjacent negative control panel shows the red and green channels acquired after omission of the primary antibodies. Scale bar: 20 µm. (D–K) Averaged time courses (mean ± SE) of wave parameters (frequency, amplitude, integral and half width) measured in 4 hf NBMNs exposed to 200 n m IbTx (D–G) or in 4 hf NBMNs exposed to 0.2 m m TEA (H–K).

Article Snippet: Iberiotoxin (IbTX) was purchased from Alomone Labs (Jerusalem, Israel).

Techniques: Immunofluorescence, Analysis, Negative Control, Patch Clamp