ska 31  (Alomone Labs)


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    Structured Review

    Alomone Labs ska 31
    LPI suppresses the hyperpolarization to Ach, but not to <t>SKA-31,</t> in the endothelium of mice aorta. (A) Effect of 3 μM LPI on endothelial hyperpolarization to 2 μM Ach (n = 4). (B) Effect of 10 μM LPI on endothelial hyperpolarization to two consecutive administrations of 2 μM Ach (n = 3). The hyperpolarization to SKA-31 (10 μM) remained unaffected by LPI pre-exposure (n = 4). (C) Representative membrane potential recording from in situ mice aortic endothelium showing a failure of LPI (10 μM) to inhibit the hyperpolarization evoked by 10 μM SKA-31 (n = 3).
    Ska 31, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ska 31/product/Alomone Labs
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    ska 31 - by Bioz Stars, 2022-07
    90/100 stars

    Images

    1) Product Images from "GPR55 agonist lysophosphatidylinositol and lysophosphatidylcholine inhibit endothelial cell hyperpolarization via GPR-independent suppression of Na+-Ca2+ exchanger and endoplasmic reticulum Ca2+ refilling"

    Article Title: GPR55 agonist lysophosphatidylinositol and lysophosphatidylcholine inhibit endothelial cell hyperpolarization via GPR-independent suppression of Na+-Ca2+ exchanger and endoplasmic reticulum Ca2+ refilling

    Journal: Vascular pharmacology

    doi: 10.1016/j.vph.2017.01.002

    LPI suppresses the hyperpolarization to Ach, but not to SKA-31, in the endothelium of mice aorta. (A) Effect of 3 μM LPI on endothelial hyperpolarization to 2 μM Ach (n = 4). (B) Effect of 10 μM LPI on endothelial hyperpolarization to two consecutive administrations of 2 μM Ach (n = 3). The hyperpolarization to SKA-31 (10 μM) remained unaffected by LPI pre-exposure (n = 4). (C) Representative membrane potential recording from in situ mice aortic endothelium showing a failure of LPI (10 μM) to inhibit the hyperpolarization evoked by 10 μM SKA-31 (n = 3).
    Figure Legend Snippet: LPI suppresses the hyperpolarization to Ach, but not to SKA-31, in the endothelium of mice aorta. (A) Effect of 3 μM LPI on endothelial hyperpolarization to 2 μM Ach (n = 4). (B) Effect of 10 μM LPI on endothelial hyperpolarization to two consecutive administrations of 2 μM Ach (n = 3). The hyperpolarization to SKA-31 (10 μM) remained unaffected by LPI pre-exposure (n = 4). (C) Representative membrane potential recording from in situ mice aortic endothelium showing a failure of LPI (10 μM) to inhibit the hyperpolarization evoked by 10 μM SKA-31 (n = 3).

    Techniques Used: Mouse Assay, In Situ

    2) Product Images from "Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells"

    Article Title: Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells

    Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    doi: 10.1007/s11481-018-9796-3

    Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p
    Figure Legend Snippet: Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p

    Techniques Used: Permeability

    3) Product Images from "Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells"

    Article Title: Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells

    Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    doi: 10.1007/s11481-018-9796-3

    Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p
    Figure Legend Snippet: Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p

    Techniques Used: Permeability

    4) Product Images from "Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells"

    Article Title: Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells

    Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    doi: 10.1007/s11481-018-9796-3

    Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p
    Figure Legend Snippet: Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p

    Techniques Used: Permeability

    5) Product Images from "Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells"

    Article Title: Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells

    Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    doi: 10.1007/s11481-018-9796-3

    Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p
    Figure Legend Snippet: Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p

    Techniques Used: Permeability

    6) Product Images from "Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells"

    Article Title: Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells

    Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    doi: 10.1007/s11481-018-9796-3

    Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p
    Figure Legend Snippet: Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p

    Techniques Used: Permeability

    7) Product Images from "GPR55 agonist lysophosphatidylinositol and lysophosphatidylcholine inhibit endothelial cell hyperpolarization via GPR-independent suppression of Na+-Ca2+ exchanger and endoplasmic reticulum Ca2+ refilling"

    Article Title: GPR55 agonist lysophosphatidylinositol and lysophosphatidylcholine inhibit endothelial cell hyperpolarization via GPR-independent suppression of Na+-Ca2+ exchanger and endoplasmic reticulum Ca2+ refilling

    Journal: Vascular pharmacology

    doi: 10.1016/j.vph.2017.01.002

    LPI suppresses the hyperpolarization to Ach, but not to SKA-31, in the endothelium of mice aorta. (A) Effect of 3 μM LPI on endothelial hyperpolarization to 2 μM Ach (n = 4). (B) Effect of 10 μM LPI on endothelial hyperpolarization to two consecutive administrations of 2 μM Ach (n = 3). The hyperpolarization to SKA-31 (10 μM) remained unaffected by LPI pre-exposure (n = 4). (C) Representative membrane potential recording from in situ mice aortic endothelium showing a failure of LPI (10 μM) to inhibit the hyperpolarization evoked by 10 μM SKA-31 (n = 3).
    Figure Legend Snippet: LPI suppresses the hyperpolarization to Ach, but not to SKA-31, in the endothelium of mice aorta. (A) Effect of 3 μM LPI on endothelial hyperpolarization to 2 μM Ach (n = 4). (B) Effect of 10 μM LPI on endothelial hyperpolarization to two consecutive administrations of 2 μM Ach (n = 3). The hyperpolarization to SKA-31 (10 μM) remained unaffected by LPI pre-exposure (n = 4). (C) Representative membrane potential recording from in situ mice aortic endothelium showing a failure of LPI (10 μM) to inhibit the hyperpolarization evoked by 10 μM SKA-31 (n = 3).

    Techniques Used: Mouse Assay, In Situ

    8) Product Images from "Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells"

    Article Title: Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells

    Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    doi: 10.1007/s11481-018-9796-3

    Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p
    Figure Legend Snippet: Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p

    Techniques Used: Permeability

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    • ska 31  (Alomone Labs)
    90
    Alomone Labs ska 31
    LPI suppresses the hyperpolarization to Ach, but not to <t>SKA-31,</t> in the endothelium of mice aorta. (A) Effect of 3 μM LPI on endothelial hyperpolarization to 2 μM Ach (n = 4). (B) Effect of 10 μM LPI on endothelial hyperpolarization to two consecutive administrations of 2 μM Ach (n = 3). The hyperpolarization to SKA-31 (10 μM) remained unaffected by LPI pre-exposure (n = 4). (C) Representative membrane potential recording from in situ mice aortic endothelium showing a failure of LPI (10 μM) to inhibit the hyperpolarization evoked by 10 μM SKA-31 (n = 3).
    Ska 31, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ska 31/product/Alomone Labs
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    ska 31 - by Bioz Stars, 2022-07
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    LPI suppresses the hyperpolarization to Ach, but not to SKA-31, in the endothelium of mice aorta. (A) Effect of 3 μM LPI on endothelial hyperpolarization to 2 μM Ach (n = 4). (B) Effect of 10 μM LPI on endothelial hyperpolarization to two consecutive administrations of 2 μM Ach (n = 3). The hyperpolarization to SKA-31 (10 μM) remained unaffected by LPI pre-exposure (n = 4). (C) Representative membrane potential recording from in situ mice aortic endothelium showing a failure of LPI (10 μM) to inhibit the hyperpolarization evoked by 10 μM SKA-31 (n = 3).

    Journal: Vascular pharmacology

    Article Title: GPR55 agonist lysophosphatidylinositol and lysophosphatidylcholine inhibit endothelial cell hyperpolarization via GPR-independent suppression of Na+-Ca2+ exchanger and endoplasmic reticulum Ca2+ refilling

    doi: 10.1016/j.vph.2017.01.002

    Figure Lengend Snippet: LPI suppresses the hyperpolarization to Ach, but not to SKA-31, in the endothelium of mice aorta. (A) Effect of 3 μM LPI on endothelial hyperpolarization to 2 μM Ach (n = 4). (B) Effect of 10 μM LPI on endothelial hyperpolarization to two consecutive administrations of 2 μM Ach (n = 3). The hyperpolarization to SKA-31 (10 μM) remained unaffected by LPI pre-exposure (n = 4). (C) Representative membrane potential recording from in situ mice aortic endothelium showing a failure of LPI (10 μM) to inhibit the hyperpolarization evoked by 10 μM SKA-31 (n = 3).

    Article Snippet: LPC16:0 (1-palmitoyl-2-hydroxy- sn - glycero -3-phosphocholine) was purchased from Avanti Polar Lipids, LPI from Sigma Aldrich, paxilline and SKA-31 were purchased from Alomone Labs, KB-R7943 was purchased from TCI Chemicals.

    Techniques: Mouse Assay, In Situ

    Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p

    Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    Article Title: Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells

    doi: 10.1007/s11481-018-9796-3

    Figure Lengend Snippet: Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p

    Article Snippet: In the presence of 50 μM of each of the three blockers, NS8593, CyPPA, and SKA-31, the permeability of the BMVEC barrier significantly increased in 24 h ( and of Online Resource 1).

    Techniques: Permeability