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Image Search Results
Journal: Frontiers in Bioengineering and Biotechnology
Article Title: Advances in nanomaterial-mediated CRISPR/Cas delivery: from lipid nanoparticles to vesicle-derived systems
doi: 10.3389/fbioe.2025.1669104
Figure Lengend Snippet: Proposed mechanism for CALAA-01. (a) Nanoparticles formed through the assembly of a linear polymer containing cyclodextrin (CDP), an adamantane-PEG conjugate (AD-PEG), a targeting element (transferrin, Tf), and the therapeutic gene (siRNA). (b) Patients receive an infusion of these nanoparticles. (c) Nanoparticles circulate and infiltrate tumors. (d) Receptor-mediated endocytosis occurs. (e) Targeted nanoparticles interact with receptors on the cancer cell surface. Reprinted from with permission from American Chemical Society.
Article Snippet: Hereditary transthyretin amyloidosis (hATTR) ,
Techniques: Polymer
Journal: Journal of Animal Science and Biotechnology
Article Title: Maternal undernutrition inhibits fetal rumen development: novel miRNA-736-mediated dual targeting of E2F2 and MYBL2 in sheep
doi: 10.1186/s40104-025-01321-7
Figure Lengend Snippet: E2F2 and MYBL2 regulated rumen epithelial cell cycle and apoptosis. A E2F2 silencing efficiency assay. B The expression of genes related to cell cycle and apoptosis transfected with siRNA- E2F2 . C Detection of rumen epithelial cell viability transfected with siRNA- E2F2 . D – E Detection of rumen epithelial cell apoptosis rate transfected with siRNA- E2F2 . F – G Cell cycle detection of rumen epithelial cells transfected with siRNA- E2F2 . H MYBL2 silencing efficiency assay. I The expression of genes related to cell cycle and apoptosis transfected with siRNA- MYBL2 . J Detection of rumen epithelial cell viability transfected with siRNA- MYBL2 . K – L Detection of rumen epithelial cell apoptosis rate transfected with siRNA- MYBL2 . M – N Cell cycle detection of rumen epithelial cells transfected with siRNA- MYBL2. The data were analyzed using two-tailed t -test for comparisons between two groups ( n = 3) or one-way ANOVA for comparisons among three groups ( n = 3), * P < 0.05
Article Snippet: The small
Techniques: Expressing, Transfection, Two Tailed Test