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Amount of Dxp extracted from Soft MA®, Miru 1 day®, 1 day Acuvue® and Miru 1 month® following rinsing for 10 s (white columns) or overnight storage (dark grey columns) with SOLOCARE AQUA® care solution ( n = 3, mean ± SD). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

Journal: International Journal of Pharmaceutics: X

Article Title: 3D printed system using ex vivo porcine eye globes to investigate intracorneal absorption of dexpanthenol from contact lens care solution and eye drops

doi: 10.1016/j.ijpx.2025.100472

Figure Lengend Snippet: Amount of Dxp extracted from Soft MA®, Miru 1 day®, 1 day Acuvue® and Miru 1 month® following rinsing for 10 s (white columns) or overnight storage (dark grey columns) with SOLOCARE AQUA® care solution ( n = 3, mean ± SD). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

Article Snippet: The experimental conditions were based on the SOLOCARE AQUA® user recommendations provided by Menicon Co. Ltd.

Techniques:

Dxp depth distribution of in corneal slices and the concentration of Dxp in the aqueous humour following the 6 h application of SOLOCARE AQUA® overnight stored soft contact lenses (Miru 1 month® and 1 day Acuvue®) and hourly eye drop instillation (5 times) of Bepanthen® and Siccaprotect®. * indicates statistically significant difference (i. aqueous humour – 3-fold higher deposition with the eye drop group vs. the contact lens group ( p < 0.0014); ii. 400–1000 μm – 3-4 fold higher deposition with eye drops ( p < 0.0108); iii. 300–400 μm – 3-4 fold higher deposition with eye drops ( p < 0.0179); iv. 200–300 μm and 100–200 μm – Bepanthan® showed higher deposition than both contact lenses but Siccaprotect® was only superior to Miru 1 month®) ( n = 6, mean ± SD). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

Journal: International Journal of Pharmaceutics: X

Article Title: 3D printed system using ex vivo porcine eye globes to investigate intracorneal absorption of dexpanthenol from contact lens care solution and eye drops

doi: 10.1016/j.ijpx.2025.100472

Figure Lengend Snippet: Dxp depth distribution of in corneal slices and the concentration of Dxp in the aqueous humour following the 6 h application of SOLOCARE AQUA® overnight stored soft contact lenses (Miru 1 month® and 1 day Acuvue®) and hourly eye drop instillation (5 times) of Bepanthen® and Siccaprotect®. * indicates statistically significant difference (i. aqueous humour – 3-fold higher deposition with the eye drop group vs. the contact lens group ( p < 0.0014); ii. 400–1000 μm – 3-4 fold higher deposition with eye drops ( p < 0.0108); iii. 300–400 μm – 3-4 fold higher deposition with eye drops ( p < 0.0179); iv. 200–300 μm and 100–200 μm – Bepanthan® showed higher deposition than both contact lenses but Siccaprotect® was only superior to Miru 1 month®) ( n = 6, mean ± SD). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

Article Snippet: The experimental conditions were based on the SOLOCARE AQUA® user recommendations provided by Menicon Co. Ltd.

Techniques: Concentration Assay, Eye Drops