Journal: Psychopharmacology

Article Title: Cocaine-induced plasticity, motivation, and cue responsivity do not differ in obesity-prone vs obesity-resistant rats; implications for food addiction

doi: 10.1007/s00213-023-06327-5

Figure Lengend Snippet: Cue-induced c-Fos expression in the NAc core ( A ), NAc shell ( B ), amgydala ( C ), and mPFC ( D ). Representative c-Fos (red) and DAPI (blue) images are shown to the right of each bar graph; scale bar = 100 microns. No differences between obesity-prone and obesity-resistant groups were found for any measure. However, cue presentation resulted in greater c-Fos expression in IntA vs control groups in the NAc core, NAc shell and amygdala. * = significant main effect of treatment

Article Snippet: Expression of c-Fos protein was determined using a Rabbit anti c-Fos primary antibody (CST, MA, #2250S) and an Alexa Fluor 555 Goat-anti-Rabbit secondary antibody (Invitrogen, MA, A32732), both at a 1:2000 dilution.

Techniques: Expressing