rabbit anti tfap2c  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc rabbit anti tfap2c
    Rabbit Anti Tfap2c, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti tfap2c/product/Cell Signaling Technology Inc
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti tfap2c - by Bioz Stars, 2023-03
    93/100 stars

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    rabbit anti tfap2c  (Cell Signaling Technology Inc)


    Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
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    Structured Review

    Cell Signaling Technology Inc rabbit anti tfap2c
    Rabbit Anti Tfap2c, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti tfap2c/product/Cell Signaling Technology Inc
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti tfap2c - by Bioz Stars, 2023-03
    93/100 stars

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    rabbit anti tfap2c  (Cell Signaling Technology Inc)


    Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
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    Cell Signaling Technology Inc rabbit anti tfap2c
    KLF17 is a key promoter of human naive pluripotency (A) Motif enrichment in HENSM-specific and primed-specific accessible chromatin regions (n = 20,642 and b = 36,927, respectively). Motif families are indicated at the right. Shades represent enrichment fold change. (B) Primed WT and KO hESCs for KLF4 and/or KLF17 were reverted in HENSM and HENSM-ACT conditions, imaged, and assayed for OCT4-GFP by FACS analysis (values indicated per frame). (C) WT and KO mESCs for Klf17 were expanded in 2iL, phase imaged, and assayed for OCT4-GFP by FACS analysis (values indicated per frame). (D) Genomic annotation of binding sites of KLF17, KLF4, <t>TFAP2C,</t> NANOG, OCT4, and SOX2 measured in HENSM naive or primed conditions, showing the preference of KLF17 to bind promoters, compared to all TFs that prefer to bind enhancers (distal intergenic + introns annotations). (E) KLF17 binding pattern (average Z score + STD) in naive-specific regions (n = 20,642, blue), primed-specific regions (n = 36,927, red), or all promoters (n = 43,463, gray). (F) Overlap between target genes of the indicated TFs, showing highest overlap between Sox2 and Oct4 target genes (p ~0) and a relative lower overlap with KLF17 and KLF4 targets (p < 10 −21 ). Scaled p value is presented . (G) ChIP-seq profile of KLF17, OCT4, and SOX2 in selected regions and different conditions in hPSCs. IGV range common to all tracks is indicated.
    Rabbit Anti Tfap2c, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti tfap2c/product/Cell Signaling Technology Inc
    Average 96 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti tfap2c - by Bioz Stars, 2023-03
    96/100 stars

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    1) Product Images from "Principles of signaling pathway modulation for enhancing human naive pluripotency induction"

    Article Title: Principles of signaling pathway modulation for enhancing human naive pluripotency induction

    Journal: Cell Stem Cell

    doi: 10.1016/j.stem.2021.04.001

    KLF17 is a key promoter of human naive pluripotency (A) Motif enrichment in HENSM-specific and primed-specific accessible chromatin regions (n = 20,642 and b = 36,927, respectively). Motif families are indicated at the right. Shades represent enrichment fold change. (B) Primed WT and KO hESCs for KLF4 and/or KLF17 were reverted in HENSM and HENSM-ACT conditions, imaged, and assayed for OCT4-GFP by FACS analysis (values indicated per frame). (C) WT and KO mESCs for Klf17 were expanded in 2iL, phase imaged, and assayed for OCT4-GFP by FACS analysis (values indicated per frame). (D) Genomic annotation of binding sites of KLF17, KLF4, TFAP2C, NANOG, OCT4, and SOX2 measured in HENSM naive or primed conditions, showing the preference of KLF17 to bind promoters, compared to all TFs that prefer to bind enhancers (distal intergenic + introns annotations). (E) KLF17 binding pattern (average Z score + STD) in naive-specific regions (n = 20,642, blue), primed-specific regions (n = 36,927, red), or all promoters (n = 43,463, gray). (F) Overlap between target genes of the indicated TFs, showing highest overlap between Sox2 and Oct4 target genes (p ~0) and a relative lower overlap with KLF17 and KLF4 targets (p < 10 −21 ). Scaled p value is presented . (G) ChIP-seq profile of KLF17, OCT4, and SOX2 in selected regions and different conditions in hPSCs. IGV range common to all tracks is indicated.
    Figure Legend Snippet: KLF17 is a key promoter of human naive pluripotency (A) Motif enrichment in HENSM-specific and primed-specific accessible chromatin regions (n = 20,642 and b = 36,927, respectively). Motif families are indicated at the right. Shades represent enrichment fold change. (B) Primed WT and KO hESCs for KLF4 and/or KLF17 were reverted in HENSM and HENSM-ACT conditions, imaged, and assayed for OCT4-GFP by FACS analysis (values indicated per frame). (C) WT and KO mESCs for Klf17 were expanded in 2iL, phase imaged, and assayed for OCT4-GFP by FACS analysis (values indicated per frame). (D) Genomic annotation of binding sites of KLF17, KLF4, TFAP2C, NANOG, OCT4, and SOX2 measured in HENSM naive or primed conditions, showing the preference of KLF17 to bind promoters, compared to all TFs that prefer to bind enhancers (distal intergenic + introns annotations). (E) KLF17 binding pattern (average Z score + STD) in naive-specific regions (n = 20,642, blue), primed-specific regions (n = 36,927, red), or all promoters (n = 43,463, gray). (F) Overlap between target genes of the indicated TFs, showing highest overlap between Sox2 and Oct4 target genes (p ~0) and a relative lower overlap with KLF17 and KLF4 targets (p < 10 −21 ). Scaled p value is presented . (G) ChIP-seq profile of KLF17, OCT4, and SOX2 in selected regions and different conditions in hPSCs. IGV range common to all tracks is indicated.

    Techniques Used: Binding Assay, ChIP-sequencing


    Figure Legend Snippet:

    Techniques Used: Recombinant, Protease Inhibitor, Methylation, Purification, DNA Methylation Assay, Transfection, Construct, Software

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    • rabbit anti tfap2c  (Cell Signaling Technology Inc)
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    Cell Signaling Technology Inc rabbit anti tfap2c
    Rabbit Anti Tfap2c, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti tfap2c/product/Cell Signaling Technology Inc
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti tfap2c - by Bioz Stars, 2023-03
    93/100 stars
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