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GraphPad Prism Inc r language 4 0 0
Serum protein profiles in patient cohorts in the current study.  (A–C)  Volcano plot exhibiting the DAPs in the T2DM, CRC and T2DM + CRC patients in comparison with healthy participants. DAPs were extracted using R language 4.0.0 with a criterion of fold change (FC) ≥ 1.50 or ≤0.67 and unpaired  t -test  p  value ≤0.05.  (D)  Hierarchical cluster analysis of the 67 DAPs in the groups of healthy participants, T2DM, CRC, and T2DM + CRC. There were five samples in each group. Red represents for high expression and blue represents for low expression.
R Language 4 0 0, supplied by GraphPad Prism Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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1) Product Images from "A Novel Diagnostic Biomarker, PZP, for Detecting Colorectal Cancer in Type 2 Diabetes Mellitus Patients Identified by Serum-Based Mass Spectrometry"

Article Title: A Novel Diagnostic Biomarker, PZP, for Detecting Colorectal Cancer in Type 2 Diabetes Mellitus Patients Identified by Serum-Based Mass Spectrometry

Journal: Frontiers in Molecular Biosciences

doi: 10.3389/fmolb.2021.736272

Serum protein profiles in patient cohorts in the current study.  (A–C)  Volcano plot exhibiting the DAPs in the T2DM, CRC and T2DM + CRC patients in comparison with healthy participants. DAPs were extracted using R language 4.0.0 with a criterion of fold change (FC) ≥ 1.50 or ≤0.67 and unpaired  t -test  p  value ≤0.05.  (D)  Hierarchical cluster analysis of the 67 DAPs in the groups of healthy participants, T2DM, CRC, and T2DM + CRC. There were five samples in each group. Red represents for high expression and blue represents for low expression.
Figure Legend Snippet: Serum protein profiles in patient cohorts in the current study. (A–C) Volcano plot exhibiting the DAPs in the T2DM, CRC and T2DM + CRC patients in comparison with healthy participants. DAPs were extracted using R language 4.0.0 with a criterion of fold change (FC) ≥ 1.50 or ≤0.67 and unpaired t -test p value ≤0.05. (D) Hierarchical cluster analysis of the 67 DAPs in the groups of healthy participants, T2DM, CRC, and T2DM + CRC. There were five samples in each group. Red represents for high expression and blue represents for low expression.

Techniques Used: Expressing

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    GraphPad Prism Inc l nebivolol
    Involvement of β 3 -adrenoceptors in the relaxant effect of <t>D-nebivolol</t> (A) and L-nebivolol (B). The mean curves are shown resulting from subtraction of the spontaneous relaxation of control rings after pre-treatment with 7 µmol·L −1 of L-748,337 (β 3 -adrenoceptor antagonist). Results are expressed as the percentage of relaxation from the maximal contraction induced by ET1. Each point is the mean of n experiments obtained from n rats and vertical lines show the SEM. When no error bar is shown, the error is smaller than the symbol. * P
    L Nebivolol, supplied by GraphPad Prism Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/l nebivolol/product/GraphPad Prism Inc
    Average 90 stars, based on 1 article reviews
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    l nebivolol - by Bioz Stars, 2022-09
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    GraphPad Prism Inc r language 4 0 0
    Serum protein profiles in patient cohorts in the current study.  (A–C)  Volcano plot exhibiting the DAPs in the T2DM, CRC and T2DM + CRC patients in comparison with healthy participants. DAPs were extracted using R language 4.0.0 with a criterion of fold change (FC) ≥ 1.50 or ≤0.67 and unpaired  t -test  p  value ≤0.05.  (D)  Hierarchical cluster analysis of the 67 DAPs in the groups of healthy participants, T2DM, CRC, and T2DM + CRC. There were five samples in each group. Red represents for high expression and blue represents for low expression.
    R Language 4 0 0, supplied by GraphPad Prism Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/r language 4 0 0/product/GraphPad Prism Inc
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    r language 4 0 0 - by Bioz Stars, 2022-09
    90/100 stars
      Buy from Supplier

    88
    GraphPad Prism Inc graphpad prism 4 0 software
    The enriched KEGG pathways in treatment-resistant cells in comparison to sensitive cells. All genes with padj ≤ 0,0001 and log fold change > 2 in U87MG and/or U138MG cells compared to T98G and/or U251MG cells were subjected to pathway analysis by KEGG. The pathways related to cell-extracellular matrix interaction were highlighted in red. A False Discovery Rate (FDR) ≤ 0.05 was used as a threshold to select significant pathways. Graphs were plotted with <t>GraphPad</t> Prism 4.0 <t>software.</t>
    Graphpad Prism 4 0 Software, supplied by GraphPad Prism Inc, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/graphpad prism 4 0 software/product/GraphPad Prism Inc
    Average 88 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    graphpad prism 4 0 software - by Bioz Stars, 2022-09
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    Image Search Results


    Involvement of β 3 -adrenoceptors in the relaxant effect of D-nebivolol (A) and L-nebivolol (B). The mean curves are shown resulting from subtraction of the spontaneous relaxation of control rings after pre-treatment with 7 µmol·L −1 of L-748,337 (β 3 -adrenoceptor antagonist). Results are expressed as the percentage of relaxation from the maximal contraction induced by ET1. Each point is the mean of n experiments obtained from n rats and vertical lines show the SEM. When no error bar is shown, the error is smaller than the symbol. * P

    Journal: British Journal of Pharmacology

    Article Title: Investigation of the different adrenoceptor targets of nebivolol enantiomers in rat thoracic aorta

    doi: 10.1111/j.1476-5381.2009.00074.x

    Figure Lengend Snippet: Involvement of β 3 -adrenoceptors in the relaxant effect of D-nebivolol (A) and L-nebivolol (B). The mean curves are shown resulting from subtraction of the spontaneous relaxation of control rings after pre-treatment with 7 µmol·L −1 of L-748,337 (β 3 -adrenoceptor antagonist). Results are expressed as the percentage of relaxation from the maximal contraction induced by ET1. Each point is the mean of n experiments obtained from n rats and vertical lines show the SEM. When no error bar is shown, the error is smaller than the symbol. * P

    Article Snippet: In the present study, pre-treatment of aortic rings by L-748,337 greatly reduced the relaxant effect of D-nebivolol (Emax = 24.1 ± 2.2%; pD2 = 5.23 ± 0.05; n = 6) and L-nebivolol (Emax = 18.9 ± 2.5%; pD2 = 5.17 ± 0.04; n = 6) ( , ).

    Techniques:

    Involvement of β 2 -adrenoceptors in the relaxant effect of D-nebivolol (A) and L-nebivolol (B). The mean curves are shown resulting from subtraction of the spontaneous relaxation of control rings after pre-treatment with 7 µmol·L −1 of ICI 118,511 (β 2 -adrenoceptor antagonist). Results are expressed as the percentage of relaxation from the maximal contraction induced by ET1. Each point is the mean of n experiments obtained from n rats and vertical lines show the SEM. When no error bar is shown, the error is smaller than the symbol. * P

    Journal: British Journal of Pharmacology

    Article Title: Investigation of the different adrenoceptor targets of nebivolol enantiomers in rat thoracic aorta

    doi: 10.1111/j.1476-5381.2009.00074.x

    Figure Lengend Snippet: Involvement of β 2 -adrenoceptors in the relaxant effect of D-nebivolol (A) and L-nebivolol (B). The mean curves are shown resulting from subtraction of the spontaneous relaxation of control rings after pre-treatment with 7 µmol·L −1 of ICI 118,511 (β 2 -adrenoceptor antagonist). Results are expressed as the percentage of relaxation from the maximal contraction induced by ET1. Each point is the mean of n experiments obtained from n rats and vertical lines show the SEM. When no error bar is shown, the error is smaller than the symbol. * P

    Article Snippet: In the present study, pre-treatment of aortic rings by L-748,337 greatly reduced the relaxant effect of D-nebivolol (Emax = 24.1 ± 2.2%; pD2 = 5.23 ± 0.05; n = 6) and L-nebivolol (Emax = 18.9 ± 2.5%; pD2 = 5.17 ± 0.04; n = 6) ( , ).

    Techniques:

    Involvement of β 1 -adrenoceptors in the relaxant effect of D-nebivolol (A) and L-nebivolol (B). The mean curves are shown resulting from subtraction of the spontaneous relaxation of control rings after pre-treatment with 1 µmol·L −1 of CGP 20,712A (β 1 -adrenoceptor antagonist). Results are expressed as the percentage of relaxation from the maximal contraction induced by ET1. Each point is the mean of n experiments obtained from n rats and vertical lines show the SEM. When no error bar is shown, the error is smaller than the symbol. ET1, endothelin 1.

    Journal: British Journal of Pharmacology

    Article Title: Investigation of the different adrenoceptor targets of nebivolol enantiomers in rat thoracic aorta

    doi: 10.1111/j.1476-5381.2009.00074.x

    Figure Lengend Snippet: Involvement of β 1 -adrenoceptors in the relaxant effect of D-nebivolol (A) and L-nebivolol (B). The mean curves are shown resulting from subtraction of the spontaneous relaxation of control rings after pre-treatment with 1 µmol·L −1 of CGP 20,712A (β 1 -adrenoceptor antagonist). Results are expressed as the percentage of relaxation from the maximal contraction induced by ET1. Each point is the mean of n experiments obtained from n rats and vertical lines show the SEM. When no error bar is shown, the error is smaller than the symbol. ET1, endothelin 1.

    Article Snippet: In the present study, pre-treatment of aortic rings by L-748,337 greatly reduced the relaxant effect of D-nebivolol (Emax = 24.1 ± 2.2%; pD2 = 5.23 ± 0.05; n = 6) and L-nebivolol (Emax = 18.9 ± 2.5%; pD2 = 5.17 ± 0.04; n = 6) ( , ).

    Techniques:

    Concentration-relaxation response curves to nebivolol racemate, D-nebivolol and L-nebivolol in rat thoracic aortic rings precontracted with ET1. The mean curves are shown resulting from substraction of the spontaneous relaxation of control rings. Results are expressed as the percentage of relaxation from the maximal contraction induced by ET1. Each point is the mean of n experiments and vertical lines show the SEM. When no error bar is shown, the error is smaller than the symbol. #, +, * P

    Journal: British Journal of Pharmacology

    Article Title: Investigation of the different adrenoceptor targets of nebivolol enantiomers in rat thoracic aorta

    doi: 10.1111/j.1476-5381.2009.00074.x

    Figure Lengend Snippet: Concentration-relaxation response curves to nebivolol racemate, D-nebivolol and L-nebivolol in rat thoracic aortic rings precontracted with ET1. The mean curves are shown resulting from substraction of the spontaneous relaxation of control rings. Results are expressed as the percentage of relaxation from the maximal contraction induced by ET1. Each point is the mean of n experiments and vertical lines show the SEM. When no error bar is shown, the error is smaller than the symbol. #, +, * P

    Article Snippet: In the present study, pre-treatment of aortic rings by L-748,337 greatly reduced the relaxant effect of D-nebivolol (Emax = 24.1 ± 2.2%; pD2 = 5.23 ± 0.05; n = 6) and L-nebivolol (Emax = 18.9 ± 2.5%; pD2 = 5.17 ± 0.04; n = 6) ( , ).

    Techniques: Concentration Assay

    Serum protein profiles in patient cohorts in the current study.  (A–C)  Volcano plot exhibiting the DAPs in the T2DM, CRC and T2DM + CRC patients in comparison with healthy participants. DAPs were extracted using R language 4.0.0 with a criterion of fold change (FC) ≥ 1.50 or ≤0.67 and unpaired  t -test  p  value ≤0.05.  (D)  Hierarchical cluster analysis of the 67 DAPs in the groups of healthy participants, T2DM, CRC, and T2DM + CRC. There were five samples in each group. Red represents for high expression and blue represents for low expression.

    Journal: Frontiers in Molecular Biosciences

    Article Title: A Novel Diagnostic Biomarker, PZP, for Detecting Colorectal Cancer in Type 2 Diabetes Mellitus Patients Identified by Serum-Based Mass Spectrometry

    doi: 10.3389/fmolb.2021.736272

    Figure Lengend Snippet: Serum protein profiles in patient cohorts in the current study. (A–C) Volcano plot exhibiting the DAPs in the T2DM, CRC and T2DM + CRC patients in comparison with healthy participants. DAPs were extracted using R language 4.0.0 with a criterion of fold change (FC) ≥ 1.50 or ≤0.67 and unpaired t -test p value ≤0.05. (D) Hierarchical cluster analysis of the 67 DAPs in the groups of healthy participants, T2DM, CRC, and T2DM + CRC. There were five samples in each group. Red represents for high expression and blue represents for low expression.

    Article Snippet: Figure exhibition was performed using R language 4.0.0 and GraphPad Prism (version 8.0).

    Techniques: Expressing

    The enriched KEGG pathways in treatment-resistant cells in comparison to sensitive cells. All genes with padj ≤ 0,0001 and log fold change > 2 in U87MG and/or U138MG cells compared to T98G and/or U251MG cells were subjected to pathway analysis by KEGG. The pathways related to cell-extracellular matrix interaction were highlighted in red. A False Discovery Rate (FDR) ≤ 0.05 was used as a threshold to select significant pathways. Graphs were plotted with GraphPad Prism 4.0 software.

    Journal: Frontiers in Oncology

    Article Title: Expression Profiling of Glioblastoma Cell Lines Reveals Novel Extracellular Matrix-Receptor Genes Correlated With the Responsiveness of Glioma Patients to Ionizing Radiation

    doi: 10.3389/fonc.2021.668090

    Figure Lengend Snippet: The enriched KEGG pathways in treatment-resistant cells in comparison to sensitive cells. All genes with padj ≤ 0,0001 and log fold change > 2 in U87MG and/or U138MG cells compared to T98G and/or U251MG cells were subjected to pathway analysis by KEGG. The pathways related to cell-extracellular matrix interaction were highlighted in red. A False Discovery Rate (FDR) ≤ 0.05 was used as a threshold to select significant pathways. Graphs were plotted with GraphPad Prism 4.0 software.

    Article Snippet: Graphs were plotted with GraphPad Prism 4.0 software.

    Techniques: Software

    The progressive accumulation of up-regulated ECM-receptor interaction genes impacts the resistance of tumors to irradiation. (A) The number of genes with expression above the threshold defined by the ROC curve was evaluated in each patient submitted to IR treatment and six categories, with an increasing number of altered genes, were defined. The percentage of alive or deceased patients included in each category is indicated. (B) Kaplan Meier survival curves for LGG patients according to the categories described in (A) . Graphs were plotted with GraphPad Prism 4.0 software.

    Journal: Frontiers in Oncology

    Article Title: Expression Profiling of Glioblastoma Cell Lines Reveals Novel Extracellular Matrix-Receptor Genes Correlated With the Responsiveness of Glioma Patients to Ionizing Radiation

    doi: 10.3389/fonc.2021.668090

    Figure Lengend Snippet: The progressive accumulation of up-regulated ECM-receptor interaction genes impacts the resistance of tumors to irradiation. (A) The number of genes with expression above the threshold defined by the ROC curve was evaluated in each patient submitted to IR treatment and six categories, with an increasing number of altered genes, were defined. The percentage of alive or deceased patients included in each category is indicated. (B) Kaplan Meier survival curves for LGG patients according to the categories described in (A) . Graphs were plotted with GraphPad Prism 4.0 software.

    Article Snippet: Graphs were plotted with GraphPad Prism 4.0 software.

    Techniques: Irradiation, Expressing, Software

    Proliferation and ionizing radiation resistance analysis in GBM cell lines. (A) Proliferation assay of T98G, U343MG, U251MG, U87MG, and U138MG. (B) Cytotoxicity assay of GBM cells after radiation treatment. (C) Quantification of apoptosis and cell death of GBM cells after irradiation are shown in the upper graphics and representative images of flow cytometry experiments are presented in the lower panel. Error bars represent the SEM of 3 independent experiments. Graphs were plotted with GraphPad Prism 4.0 software. *p

    Journal: Frontiers in Oncology

    Article Title: Expression Profiling of Glioblastoma Cell Lines Reveals Novel Extracellular Matrix-Receptor Genes Correlated With the Responsiveness of Glioma Patients to Ionizing Radiation

    doi: 10.3389/fonc.2021.668090

    Figure Lengend Snippet: Proliferation and ionizing radiation resistance analysis in GBM cell lines. (A) Proliferation assay of T98G, U343MG, U251MG, U87MG, and U138MG. (B) Cytotoxicity assay of GBM cells after radiation treatment. (C) Quantification of apoptosis and cell death of GBM cells after irradiation are shown in the upper graphics and representative images of flow cytometry experiments are presented in the lower panel. Error bars represent the SEM of 3 independent experiments. Graphs were plotted with GraphPad Prism 4.0 software. *p

    Article Snippet: Graphs were plotted with GraphPad Prism 4.0 software.

    Techniques: Proliferation Assay, Cytotoxicity Assay, Irradiation, Flow Cytometry, Software