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Becton Dickinson plasma dabigatran concentrations
Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma <t>dabigatran</t> concentrations. For TT, all
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1) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

2) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

3) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

4) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

5) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

6) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

7) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

8) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

9) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

10) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

11) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

12) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

13) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

14) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

15) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

16) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

17) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

18) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

19) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

20) Product Images from "Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran"

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

Journal: British Journal of Clinical Pharmacology

doi: 10.1111/bcp.12366

Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all
Figure Legend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

Techniques Used:

(A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations
Figure Legend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

Techniques Used:

Related Articles

other:

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran
Article Snippet: This range encompasses > 90% of the plasma dabigatran concentrations reported in each of the real-world dabigatran studies, including the present study – .

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran
Article Snippet: In this setting, it has been suggested that TT would be useful to cover the lower, and the aPTT and INR to cover the higher, plasma dabigatran concentrations.

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran
Article Snippet: The apparent lack of proportional variance in the relationship between the HTI and plasma dabigatran concentrations is an interesting phenomenon (Figure ).

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran
Article Snippet: Hence, the INR and aPTT have been regarded as being relatively insensitive to plasma dabigatran concentrations, particularly in comparison to the TT and HTI assays .

Article Title: Correlation Between Trough Plasma Dabigatran Concentrations and Estimates of Glomerular Filtration Rate Based on Creatinine and Cystatin C
Article Snippet: Sample Collection and Laboratory Analysis Each patient provided a set of venous blood samples 10–16 hours post-dose for measuring plasma creatinine and cystatin C concentrations, plasma free thyroxine and thyroid-stimulating hormone (TSH) concentrations (BD Vacutainer® lithium heparin tubes); Hemoclot® Thrombin Inhibitor times (HTI, Hyphen BioMed, Neuville-sur-Oise, France) (BD Vacutainer® citrate tubes); plasma dabigatran concentrations (BD Vacutainer® K2 ethylene diamine tetraacetic acid [EDTA] tubes).

Coagulation:

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran
Article Snippet: Statistical analysis was performed using GraphPad Prism (version 6.03; GraphPad Software, La Jolla, CA, USA; ) and SPSS (IBM SPSS Statistics for Windows, version 20.0.0.2; IBM Corporation, Armonk, NY, USA). .. Linear regression analyses were used to determine the lines of best fit, and the coefficient of determination ( r 2 ) was used to describe the relationships between the coagulation assays and plasma dabigatran concentrations. ..

Thrombin Time Assay:

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran
Article Snippet: The TT assay we used consistently resulted in times greater than the maximal reported time at plasma dabigatran concentrations > 74 μg l−1 in our study, while Hawes et al . reported that that this value was 138 μg l−1 with the TT assay they used . .. In contrast, data from Stangier et al . demonstrate that the TT assay they used (Biomatic B10 coagulometer; Desaga, Wiesloch, Germany) could measure TT values for plasma dabigatran concentrations of 0 to ∼400 μg l−1 , . .. This range encompasses > 90% of the plasma dabigatran concentrations reported in each of the real-world dabigatran studies, including the present study – .

Concentration Assay:

Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran
Article Snippet: .. Given that one of the major differences between the HTI and TT assays is that the interindividual variability in plasma fibrinogen concentration is minimized in the HTI ( r 2 = 0.95 against plasma dabigatran concentrations) compared with the TT ( r 2 = 0.70), we hypothesized that including fibrinogen concentrations in the regression analysis would account for some of the explained variability of plasma dabigatran concentrations in relationship to the TT. .. While we demonstrated a statistically significant contribution to the explained variability of TT with plasma fibrinogen concentrations, the resulting r 2 = 0.74 for the combination of plasma fibrinogen and dabigatran concentrations for TT was only slightly greater than that observed with plasma dabigatran concentrations alone ( r 2 = 0.70).

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    Becton Dickinson plasma dabigatran concentrations
    Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma <t>dabigatran</t> concentrations. For TT, all
    Plasma Dabigatran Concentrations, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

    Journal: British Journal of Clinical Pharmacology

    Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

    doi: 10.1111/bcp.12366

    Figure Lengend Snippet: Correlation plots for 120 samples of international normalized ratio (INR; A), activated partial thromboplastin time (aPTT; B), thrombin time (TT; C) and Hemoclot® Thrombin Inhibitor (HTI; D) against plasma dabigatran concentrations. For TT, all

    Article Snippet: The apparent lack of proportional variance in the relationship between the HTI and plasma dabigatran concentrations is an interesting phenomenon (Figure ).

    Techniques:

    (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

    Journal: British Journal of Clinical Pharmacology

    Article Title: Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran

    doi: 10.1111/bcp.12366

    Figure Lengend Snippet: (A) Correlation plot of plasma fibrinogen concentrations against thrombin time (TT; for 120 samples, TT > 300 s have been set to 300 s). (B) Correlation plot of standardized residuals (from the linear regression of plasma dabigatran concentrations

    Article Snippet: The apparent lack of proportional variance in the relationship between the HTI and plasma dabigatran concentrations is an interesting phenomenon (Figure ).

    Techniques: