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Makeup of the BioPAX models from three resources (PID, KEGG, ACSN). The BioPAX files of the three resources were parsed in order to identify Physical Entities, Controls ( Catalysis and TemplateReactionRegulation ) and Reactions ( Conversion and TemplateReaction ). For the ACSN resources, Physical Entities were curated in order to reanotate their types when possible. The curation processes focused on compressing duplicate entities and creating controls (with the type catalysis) for reactions where a reactant is also a product.

Journal: PLoS Computational Biology

Article Title: Discrete modeling for integration and analysis of large-scale signaling networks

doi: 10.1371/journal.pcbi.1010175

Figure Lengend Snippet: Makeup of the BioPAX models from three resources (PID, KEGG, ACSN). The BioPAX files of the three resources were parsed in order to identify Physical Entities, Controls ( Catalysis and TemplateReactionRegulation ) and Reactions ( Conversion and TemplateReaction ). For the ACSN resources, Physical Entities were curated in order to reanotate their types when possible. The curation processes focused on compressing duplicate entities and creating controls (with the type catalysis) for reactions where a reactant is also a product.

Article Snippet: We performed a systematic content analysis of 2 databases available on Pathway Commons, PID (cell signaling) and KEGG (metabolism and signaling reactions), as well as the ACSN database (Cancer signaling network), which are the largest reaction databases available in the BioPAX format.

Techniques: Control

Characteristics of the Cadbiom models obtained after the conversion of BioPAX sources into models with guarded transitions. The Cadbiom models are described by entities, events and transitions. They are compared to the numbers of entities and reactions in the BioPAX models. The boundary entities correspond to the peripherical entities of the model. They are described according to their type and their role in the cadbiom model.

Journal: PLoS Computational Biology

Article Title: Discrete modeling for integration and analysis of large-scale signaling networks

doi: 10.1371/journal.pcbi.1010175

Figure Lengend Snippet: Characteristics of the Cadbiom models obtained after the conversion of BioPAX sources into models with guarded transitions. The Cadbiom models are described by entities, events and transitions. They are compared to the numbers of entities and reactions in the BioPAX models. The boundary entities correspond to the peripherical entities of the model. They are described according to their type and their role in the cadbiom model.

Article Snippet: We performed a systematic content analysis of 2 databases available on Pathway Commons, PID (cell signaling) and KEGG (metabolism and signaling reactions), as well as the ACSN database (Cancer signaling network), which are the largest reaction databases available in the BioPAX format.

Techniques: Control