phosphorylated extracellular signal regulated kinase p erk 1 2  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc phosphorylated extracellular signal regulated kinase p erk 1 2
    Curcumin ameliorates hepatic cellular senescence by regulating the p38-MAPK signaling pathway in HFHSD-fed aged mice. Immunoblots and protein expression levels in the liver tissue lysates after 15 weeks of dietary interventions: ( A ) <t>p-ERK1/2,</t> ERK1/2, and <t>p-ERK/ERK</t> ratio; ( B ) p-JNK, JNK, and p-JNK/JNK ratio; ( C ) p-p38, p38, and p-p38/p38 ratio; and ( D ) p-MK2, MK2, and p-MK2/MK2 ratio. The results are expressed as mean ± SEM (* p < 0.05).
    Phosphorylated Extracellular Signal Regulated Kinase P Erk 1 2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phosphorylated extracellular signal regulated kinase p erk 1 2/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    phosphorylated extracellular signal regulated kinase p erk 1 2 - by Bioz Stars, 2024-07
    86/100 stars

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    1) Product Images from "Dietary Curcumin Attenuates Hepatic Cellular Senescence by Suppressing the MAPK/NF-κB Signaling Pathway in Aged Mice"

    Article Title: Dietary Curcumin Attenuates Hepatic Cellular Senescence by Suppressing the MAPK/NF-κB Signaling Pathway in Aged Mice

    Journal: Antioxidants

    doi: 10.3390/antiox12061165

    Curcumin ameliorates hepatic cellular senescence by regulating the p38-MAPK signaling pathway in HFHSD-fed aged mice. Immunoblots and protein expression levels in the liver tissue lysates after 15 weeks of dietary interventions: ( A ) p-ERK1/2, ERK1/2, and p-ERK/ERK ratio; ( B ) p-JNK, JNK, and p-JNK/JNK ratio; ( C ) p-p38, p38, and p-p38/p38 ratio; and ( D ) p-MK2, MK2, and p-MK2/MK2 ratio. The results are expressed as mean ± SEM (* p < 0.05).
    Figure Legend Snippet: Curcumin ameliorates hepatic cellular senescence by regulating the p38-MAPK signaling pathway in HFHSD-fed aged mice. Immunoblots and protein expression levels in the liver tissue lysates after 15 weeks of dietary interventions: ( A ) p-ERK1/2, ERK1/2, and p-ERK/ERK ratio; ( B ) p-JNK, JNK, and p-JNK/JNK ratio; ( C ) p-p38, p38, and p-p38/p38 ratio; and ( D ) p-MK2, MK2, and p-MK2/MK2 ratio. The results are expressed as mean ± SEM (* p < 0.05).

    Techniques Used: Western Blot, Expressing

    phosphorylated extracellular signal regulated kinase p erk 1 2  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc phosphorylated extracellular signal regulated kinase p erk 1 2
    Phosphorylated Extracellular Signal Regulated Kinase P Erk 1 2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    anti phosphorylated extracellular signal regulated kinase p erk 1 2  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc anti phosphorylated extracellular signal regulated kinase p erk 1 2
    Anti Phosphorylated Extracellular Signal Regulated Kinase P Erk 1 2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Structured Review

    Santa Cruz Biotechnology phosphorylated extracellular signal regulated kinase
    Phosphorylated Extracellular Signal Regulated Kinase, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    phosphorylated extracellular signal regulated kinase 1 2  (Santa Cruz Biotechnology)

     
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    Santa Cruz Biotechnology phosphorylated extracellular signal regulated kinase 1 2
    Phosphorylated Extracellular Signal Regulated Kinase 1 2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    phosphorylated extracellular signal regulated kinase p erk  (Santa Cruz Biotechnology)

     
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    Santa Cruz Biotechnology phosphorylated extracellular signal regulated kinase p erk
    Phosphorylated Extracellular Signal Regulated Kinase P Erk, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    phosphorylated extracellular signal regulated kinase p erk 1 2 mapk  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc phosphorylated extracellular signal regulated kinase p erk 1 2 mapk
    ( A – D ) Activation of <t>ERK,</t> Akt, p38, and JNK by Western blot analysis. Normal human epidermal keratinocyte cells were cultured in 60 mm tissue-culture dishes at a density of 9.5 × 103 cells/cm 2 . The cells were exposed to 12.5 and 25 μg/mL PtNPs for 0.5, 4, and 24 hours. Untreated cells, harvested together at the 0.5-hour time point, served as a control. At the time of NP addition, the whole medium was exchanged in both treated and untreated cells. Tubulin was used as an internal control to monitor for equal loading. The data are representative of three independent experiments. Abbreviations: PtNPs, platinum nanoparticles; <t>p-ERK,</t> phosphorylated extracellular signal-regulated kinase; p-Akt, phosphorylated protein kinase B; p-JNK, phosphorylated c-Jun N-terminal kinase; Akt, protein kinase B.
    Phosphorylated Extracellular Signal Regulated Kinase P Erk 1 2 Mapk, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phosphorylated extracellular signal regulated kinase p erk 1 2 mapk/product/Cell Signaling Technology Inc
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    1) Product Images from "Effects triggered by platinum nanoparticles on primary keratinocytes"

    Article Title: Effects triggered by platinum nanoparticles on primary keratinocytes

    Journal: International Journal of Nanomedicine

    doi: 10.2147/IJN.S49612

    ( A – D ) Activation of ERK, Akt, p38, and JNK by Western blot analysis. Normal human epidermal keratinocyte cells were cultured in 60 mm tissue-culture dishes at a density of 9.5 × 103 cells/cm 2 . The cells were exposed to 12.5 and 25 μg/mL PtNPs for 0.5, 4, and 24 hours. Untreated cells, harvested together at the 0.5-hour time point, served as a control. At the time of NP addition, the whole medium was exchanged in both treated and untreated cells. Tubulin was used as an internal control to monitor for equal loading. The data are representative of three independent experiments. Abbreviations: PtNPs, platinum nanoparticles; p-ERK, phosphorylated extracellular signal-regulated kinase; p-Akt, phosphorylated protein kinase B; p-JNK, phosphorylated c-Jun N-terminal kinase; Akt, protein kinase B.
    Figure Legend Snippet: ( A – D ) Activation of ERK, Akt, p38, and JNK by Western blot analysis. Normal human epidermal keratinocyte cells were cultured in 60 mm tissue-culture dishes at a density of 9.5 × 103 cells/cm 2 . The cells were exposed to 12.5 and 25 μg/mL PtNPs for 0.5, 4, and 24 hours. Untreated cells, harvested together at the 0.5-hour time point, served as a control. At the time of NP addition, the whole medium was exchanged in both treated and untreated cells. Tubulin was used as an internal control to monitor for equal loading. The data are representative of three independent experiments. Abbreviations: PtNPs, platinum nanoparticles; p-ERK, phosphorylated extracellular signal-regulated kinase; p-Akt, phosphorylated protein kinase B; p-JNK, phosphorylated c-Jun N-terminal kinase; Akt, protein kinase B.

    Techniques Used: Activation Assay, Western Blot, Cell Culture

    anti phosphorylated extracellular signal regulated kinase p erk 1 2  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc anti phosphorylated extracellular signal regulated kinase p erk 1 2
    Anti Phosphorylated Extracellular Signal Regulated Kinase P Erk 1 2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    antibody phosphorylated extracellular signal regulated kinase p erk 1 2  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc antibody phosphorylated extracellular signal regulated kinase p erk 1 2
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    phosphorylated extracellular signal regulated kinase 1 2 p erk  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc phosphorylated extracellular signal regulated kinase 1 2 p erk
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    Cell Signaling Technology Inc phosphorylated extracellular signal regulated kinase p erk 1 2
    Curcumin ameliorates hepatic cellular senescence by regulating the p38-MAPK signaling pathway in HFHSD-fed aged mice. Immunoblots and protein expression levels in the liver tissue lysates after 15 weeks of dietary interventions: ( A ) <t>p-ERK1/2,</t> ERK1/2, and <t>p-ERK/ERK</t> ratio; ( B ) p-JNK, JNK, and p-JNK/JNK ratio; ( C ) p-p38, p38, and p-p38/p38 ratio; and ( D ) p-MK2, MK2, and p-MK2/MK2 ratio. The results are expressed as mean ± SEM (* p < 0.05).
    Phosphorylated Extracellular Signal Regulated Kinase P Erk 1 2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Cell Signaling Technology Inc anti phosphorylated extracellular signal regulated kinase p erk 1 2
    Curcumin ameliorates hepatic cellular senescence by regulating the p38-MAPK signaling pathway in HFHSD-fed aged mice. Immunoblots and protein expression levels in the liver tissue lysates after 15 weeks of dietary interventions: ( A ) <t>p-ERK1/2,</t> ERK1/2, and <t>p-ERK/ERK</t> ratio; ( B ) p-JNK, JNK, and p-JNK/JNK ratio; ( C ) p-p38, p38, and p-p38/p38 ratio; and ( D ) p-MK2, MK2, and p-MK2/MK2 ratio. The results are expressed as mean ± SEM (* p < 0.05).
    Anti Phosphorylated Extracellular Signal Regulated Kinase P Erk 1 2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Santa Cruz Biotechnology phosphorylated extracellular signal regulated kinase
    Curcumin ameliorates hepatic cellular senescence by regulating the p38-MAPK signaling pathway in HFHSD-fed aged mice. Immunoblots and protein expression levels in the liver tissue lysates after 15 weeks of dietary interventions: ( A ) <t>p-ERK1/2,</t> ERK1/2, and <t>p-ERK/ERK</t> ratio; ( B ) p-JNK, JNK, and p-JNK/JNK ratio; ( C ) p-p38, p38, and p-p38/p38 ratio; and ( D ) p-MK2, MK2, and p-MK2/MK2 ratio. The results are expressed as mean ± SEM (* p < 0.05).
    Phosphorylated Extracellular Signal Regulated Kinase, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Curcumin ameliorates hepatic cellular senescence by regulating the p38-MAPK signaling pathway in HFHSD-fed aged mice. Immunoblots and protein expression levels in the liver tissue lysates after 15 weeks of dietary interventions: ( A ) <t>p-ERK1/2,</t> ERK1/2, and <t>p-ERK/ERK</t> ratio; ( B ) p-JNK, JNK, and p-JNK/JNK ratio; ( C ) p-p38, p38, and p-p38/p38 ratio; and ( D ) p-MK2, MK2, and p-MK2/MK2 ratio. The results are expressed as mean ± SEM (* p < 0.05).
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    Santa Cruz Biotechnology phosphorylated extracellular signal regulated kinase p erk
    Curcumin ameliorates hepatic cellular senescence by regulating the p38-MAPK signaling pathway in HFHSD-fed aged mice. Immunoblots and protein expression levels in the liver tissue lysates after 15 weeks of dietary interventions: ( A ) <t>p-ERK1/2,</t> ERK1/2, and <t>p-ERK/ERK</t> ratio; ( B ) p-JNK, JNK, and p-JNK/JNK ratio; ( C ) p-p38, p38, and p-p38/p38 ratio; and ( D ) p-MK2, MK2, and p-MK2/MK2 ratio. The results are expressed as mean ± SEM (* p < 0.05).
    Phosphorylated Extracellular Signal Regulated Kinase P Erk, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Cell Signaling Technology Inc phosphorylated extracellular signal regulated kinase p erk 1 2 mapk
    ( A – D ) Activation of <t>ERK,</t> Akt, p38, and JNK by Western blot analysis. Normal human epidermal keratinocyte cells were cultured in 60 mm tissue-culture dishes at a density of 9.5 × 103 cells/cm 2 . The cells were exposed to 12.5 and 25 μg/mL PtNPs for 0.5, 4, and 24 hours. Untreated cells, harvested together at the 0.5-hour time point, served as a control. At the time of NP addition, the whole medium was exchanged in both treated and untreated cells. Tubulin was used as an internal control to monitor for equal loading. The data are representative of three independent experiments. Abbreviations: PtNPs, platinum nanoparticles; <t>p-ERK,</t> phosphorylated extracellular signal-regulated kinase; p-Akt, phosphorylated protein kinase B; p-JNK, phosphorylated c-Jun N-terminal kinase; Akt, protein kinase B.
    Phosphorylated Extracellular Signal Regulated Kinase P Erk 1 2 Mapk, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Cell Signaling Technology Inc antibody phosphorylated extracellular signal regulated kinase p erk 1 2
    ( A – D ) Activation of <t>ERK,</t> Akt, p38, and JNK by Western blot analysis. Normal human epidermal keratinocyte cells were cultured in 60 mm tissue-culture dishes at a density of 9.5 × 103 cells/cm 2 . The cells were exposed to 12.5 and 25 μg/mL PtNPs for 0.5, 4, and 24 hours. Untreated cells, harvested together at the 0.5-hour time point, served as a control. At the time of NP addition, the whole medium was exchanged in both treated and untreated cells. Tubulin was used as an internal control to monitor for equal loading. The data are representative of three independent experiments. Abbreviations: PtNPs, platinum nanoparticles; <t>p-ERK,</t> phosphorylated extracellular signal-regulated kinase; p-Akt, phosphorylated protein kinase B; p-JNK, phosphorylated c-Jun N-terminal kinase; Akt, protein kinase B.
    Antibody Phosphorylated Extracellular Signal Regulated Kinase P Erk 1 2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Cell Signaling Technology Inc phosphorylated extracellular signal regulated kinase 1 2 p erk
    ( A – D ) Activation of <t>ERK,</t> Akt, p38, and JNK by Western blot analysis. Normal human epidermal keratinocyte cells were cultured in 60 mm tissue-culture dishes at a density of 9.5 × 103 cells/cm 2 . The cells were exposed to 12.5 and 25 μg/mL PtNPs for 0.5, 4, and 24 hours. Untreated cells, harvested together at the 0.5-hour time point, served as a control. At the time of NP addition, the whole medium was exchanged in both treated and untreated cells. Tubulin was used as an internal control to monitor for equal loading. The data are representative of three independent experiments. Abbreviations: PtNPs, platinum nanoparticles; <t>p-ERK,</t> phosphorylated extracellular signal-regulated kinase; p-Akt, phosphorylated protein kinase B; p-JNK, phosphorylated c-Jun N-terminal kinase; Akt, protein kinase B.
    Phosphorylated Extracellular Signal Regulated Kinase 1 2 P Erk, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Curcumin ameliorates hepatic cellular senescence by regulating the p38-MAPK signaling pathway in HFHSD-fed aged mice. Immunoblots and protein expression levels in the liver tissue lysates after 15 weeks of dietary interventions: ( A ) p-ERK1/2, ERK1/2, and p-ERK/ERK ratio; ( B ) p-JNK, JNK, and p-JNK/JNK ratio; ( C ) p-p38, p38, and p-p38/p38 ratio; and ( D ) p-MK2, MK2, and p-MK2/MK2 ratio. The results are expressed as mean ± SEM (* p < 0.05).

    Journal: Antioxidants

    Article Title: Dietary Curcumin Attenuates Hepatic Cellular Senescence by Suppressing the MAPK/NF-κB Signaling Pathway in Aged Mice

    doi: 10.3390/antiox12061165

    Figure Lengend Snippet: Curcumin ameliorates hepatic cellular senescence by regulating the p38-MAPK signaling pathway in HFHSD-fed aged mice. Immunoblots and protein expression levels in the liver tissue lysates after 15 weeks of dietary interventions: ( A ) p-ERK1/2, ERK1/2, and p-ERK/ERK ratio; ( B ) p-JNK, JNK, and p-JNK/JNK ratio; ( C ) p-p38, p38, and p-p38/p38 ratio; and ( D ) p-MK2, MK2, and p-MK2/MK2 ratio. The results are expressed as mean ± SEM (* p < 0.05).

    Article Snippet: The membranes were blocked in a blocking reagent (LI-COR, Lincoln, NE, USA) at room temperature for 1 h and incubated with the primary antibodies at 4 °C overnight as follows: phosphorylated extracellular signal-regulated kinase (p-ERK) 1/2, ERK1/2, phosphorylated c-Jun N-terminal kinase (p-JNK) 1/2, JNK1/2, p-p38, p38, phosphorylated MAP kinase-activated protein kinase 2 (p-MK2), MK2, p-p65, p65, p53, cyclophilin B, histone deacetylase 1 (HDAC1), β-tubulin, and β-actin from Cell Signaling Technology (Danvers, MA, USA).

    Techniques: Western Blot, Expressing

    ( A – D ) Activation of ERK, Akt, p38, and JNK by Western blot analysis. Normal human epidermal keratinocyte cells were cultured in 60 mm tissue-culture dishes at a density of 9.5 × 103 cells/cm 2 . The cells were exposed to 12.5 and 25 μg/mL PtNPs for 0.5, 4, and 24 hours. Untreated cells, harvested together at the 0.5-hour time point, served as a control. At the time of NP addition, the whole medium was exchanged in both treated and untreated cells. Tubulin was used as an internal control to monitor for equal loading. The data are representative of three independent experiments. Abbreviations: PtNPs, platinum nanoparticles; p-ERK, phosphorylated extracellular signal-regulated kinase; p-Akt, phosphorylated protein kinase B; p-JNK, phosphorylated c-Jun N-terminal kinase; Akt, protein kinase B.

    Journal: International Journal of Nanomedicine

    Article Title: Effects triggered by platinum nanoparticles on primary keratinocytes

    doi: 10.2147/IJN.S49612

    Figure Lengend Snippet: ( A – D ) Activation of ERK, Akt, p38, and JNK by Western blot analysis. Normal human epidermal keratinocyte cells were cultured in 60 mm tissue-culture dishes at a density of 9.5 × 103 cells/cm 2 . The cells were exposed to 12.5 and 25 μg/mL PtNPs for 0.5, 4, and 24 hours. Untreated cells, harvested together at the 0.5-hour time point, served as a control. At the time of NP addition, the whole medium was exchanged in both treated and untreated cells. Tubulin was used as an internal control to monitor for equal loading. The data are representative of three independent experiments. Abbreviations: PtNPs, platinum nanoparticles; p-ERK, phosphorylated extracellular signal-regulated kinase; p-Akt, phosphorylated protein kinase B; p-JNK, phosphorylated c-Jun N-terminal kinase; Akt, protein kinase B.

    Article Snippet: The following antibodies and dilutions were used: Akt (1:1,000; Cell Signaling Technology, Danvers, MA, USA), Phospho-Akt (1:2,000; Cell Signaling Technology), stress-activated protein kinase (SAPK)/c-Jun N-terminal kinase (JNK) (1:500; Cell Signaling Technology), Phospho-SAPK/JNK (1:500; Cell Signaling Technology), p38 MAPK (1:1,000; Cell Signaling Technology), Phospho-p38 MAPK (1:500; Cell Signaling Technology), phosphorylated extracellular signal-regulated kinase (p-ERK)-1/2 MAPK (1:2,000; Cell Signaling Technology), Phospho-ERK1/2 MAPK (1:1,000; Cell Signaling Technology).

    Techniques: Activation Assay, Western Blot, Cell Culture