Review





Similar Products

paraformaldehyde pfa  (Boston BioProducts)
96
Boston BioProducts paraformaldehyde pfa
Paraformaldehyde Pfa, supplied by Boston BioProducts, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pfa/Paraformaldehyde/pmc13019076-356-6-8
Average 96 stars, based on 1 article reviews
paraformaldehyde pfa - by Bioz Stars, 2026-09
96/100 stars
  Buy from Supplier
paraformaldehyde pfa  (Thermo Fisher)
95
Thermo Fisher paraformaldehyde pfa
Paraformaldehyde Pfa, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pfa/Paraformaldehyde%2C+32%25+w%2Fv+aq%2E+soln%2E%2C+methanol+free/pm42357299-142-13-16
Average 95 stars, based on 1 article reviews
paraformaldehyde pfa - by Bioz Stars, 2026-09
95/100 stars
  Buy from Supplier
innovance pfa 200 system  (Siemens Healthineers)
86
Siemens Healthineers innovance pfa 200 system
PSG6 inhibits platelet function without inducing cytotoxicity or impairing hemostasis . (A) Platelet cytotoxicity by LDH release. (B) Platelet apoptosis by Annexin-V (phosphatidylserine externalization). (C) Platelet viability by Calcein-AM. (D) Platelet aggregation induced with TRAP-6 at 5 μM of gentisic acid linked to TPP by different chain lengths. (E) P-Selectin expression (PE-CD62p). (F) Activated IIb/IIIa (FITC-Fibrinogen) (G) Representative image of clot retraction assay and clot weight after 2 h. <t>(H–I)</t> <t>PFA-200</t> closure times in collagen/ADP and collagen/epinephrine cartridges, respectively. Eptifibatide (EPT) 10 μM was used as a control for G–I. (J) Representative fluorescence microscopy images of thrombus formation on 3 different areas of collagen-coated channels under arterial shear conditions, showing vehicle (DMSO 0.2%) versus PSG6 at 10 μM. Thrombus coverage is expressed as the percentage of surface area occupied by fluorescently marked platelets. (K) Quantification of thrombus area based on fluorescence intensity of platelet-specific markers, using a defined threshold to exclude non-platelet signals. For A-F, data is shown as mean ± SEM (n = 6). One-way ANOVA – Bonferroni was performed as a statistical analysis. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001 vs vehicle (DMSO 0.2%). For G-K, data are -presented as mean ± SEM (n = 3). One-way ANOVA with Bonferroni's post hoc test was used for statistical analysis. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 vs. vehicle (DMSO 0.2%).
Innovance Pfa 200 System, supplied by Siemens Healthineers, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pfa/analyzer+function+platelet/pmc13202023-72-19-22
Average 86 stars, based on 1 article reviews
innovance pfa 200 system - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier
w v paraformaldehyde pfa thermo fisher scientific j19943 k2  (Thermo Fisher)
99
Thermo Fisher w v paraformaldehyde pfa thermo fisher scientific j19943 k2
PSG6 inhibits platelet function without inducing cytotoxicity or impairing hemostasis . (A) Platelet cytotoxicity by LDH release. (B) Platelet apoptosis by Annexin-V (phosphatidylserine externalization). (C) Platelet viability by Calcein-AM. (D) Platelet aggregation induced with TRAP-6 at 5 μM of gentisic acid linked to TPP by different chain lengths. (E) P-Selectin expression (PE-CD62p). (F) Activated IIb/IIIa (FITC-Fibrinogen) (G) Representative image of clot retraction assay and clot weight after 2 h. <t>(H–I)</t> <t>PFA-200</t> closure times in collagen/ADP and collagen/epinephrine cartridges, respectively. Eptifibatide (EPT) 10 μM was used as a control for G–I. (J) Representative fluorescence microscopy images of thrombus formation on 3 different areas of collagen-coated channels under arterial shear conditions, showing vehicle (DMSO 0.2%) versus PSG6 at 10 μM. Thrombus coverage is expressed as the percentage of surface area occupied by fluorescently marked platelets. (K) Quantification of thrombus area based on fluorescence intensity of platelet-specific markers, using a defined threshold to exclude non-platelet signals. For A-F, data is shown as mean ± SEM (n = 6). One-way ANOVA – Bonferroni was performed as a statistical analysis. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001 vs vehicle (DMSO 0.2%). For G-K, data are -presented as mean ± SEM (n = 3). One-way ANOVA with Bonferroni's post hoc test was used for statistical analysis. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 vs. vehicle (DMSO 0.2%).
W V Paraformaldehyde Pfa Thermo Fisher Scientific J19943 K2, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pfa/Paraformaldehyde+Solution%2C+4%25+in+PBS/pm42343134-500-13-16
Average 99 stars, based on 1 article reviews
w v paraformaldehyde pfa thermo fisher scientific j19943 k2 - by Bioz Stars, 2026-09
99/100 stars
  Buy from Supplier
paraformaldehyde pfa  (Nacalai)
86
Nacalai paraformaldehyde pfa
PSG6 inhibits platelet function without inducing cytotoxicity or impairing hemostasis . (A) Platelet cytotoxicity by LDH release. (B) Platelet apoptosis by Annexin-V (phosphatidylserine externalization). (C) Platelet viability by Calcein-AM. (D) Platelet aggregation induced with TRAP-6 at 5 μM of gentisic acid linked to TPP by different chain lengths. (E) P-Selectin expression (PE-CD62p). (F) Activated IIb/IIIa (FITC-Fibrinogen) (G) Representative image of clot retraction assay and clot weight after 2 h. <t>(H–I)</t> <t>PFA-200</t> closure times in collagen/ADP and collagen/epinephrine cartridges, respectively. Eptifibatide (EPT) 10 μM was used as a control for G–I. (J) Representative fluorescence microscopy images of thrombus formation on 3 different areas of collagen-coated channels under arterial shear conditions, showing vehicle (DMSO 0.2%) versus PSG6 at 10 μM. Thrombus coverage is expressed as the percentage of surface area occupied by fluorescently marked platelets. (K) Quantification of thrombus area based on fluorescence intensity of platelet-specific markers, using a defined threshold to exclude non-platelet signals. For A-F, data is shown as mean ± SEM (n = 6). One-way ANOVA – Bonferroni was performed as a statistical analysis. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001 vs vehicle (DMSO 0.2%). For G-K, data are -presented as mean ± SEM (n = 3). One-way ANOVA with Bonferroni's post hoc test was used for statistical analysis. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 vs. vehicle (DMSO 0.2%).
Paraformaldehyde Pfa, supplied by Nacalai, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pfa/paraformaldehyde/pmc13267569-13-0-3
Average 86 stars, based on 1 article reviews
paraformaldehyde pfa - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier
w v paraformaldehyde pfa nacalai tesque  (Nacalai)
86
Nacalai w v paraformaldehyde pfa nacalai tesque
PSG6 inhibits platelet function without inducing cytotoxicity or impairing hemostasis . (A) Platelet cytotoxicity by LDH release. (B) Platelet apoptosis by Annexin-V (phosphatidylserine externalization). (C) Platelet viability by Calcein-AM. (D) Platelet aggregation induced with TRAP-6 at 5 μM of gentisic acid linked to TPP by different chain lengths. (E) P-Selectin expression (PE-CD62p). (F) Activated IIb/IIIa (FITC-Fibrinogen) (G) Representative image of clot retraction assay and clot weight after 2 h. <t>(H–I)</t> <t>PFA-200</t> closure times in collagen/ADP and collagen/epinephrine cartridges, respectively. Eptifibatide (EPT) 10 μM was used as a control for G–I. (J) Representative fluorescence microscopy images of thrombus formation on 3 different areas of collagen-coated channels under arterial shear conditions, showing vehicle (DMSO 0.2%) versus PSG6 at 10 μM. Thrombus coverage is expressed as the percentage of surface area occupied by fluorescently marked platelets. (K) Quantification of thrombus area based on fluorescence intensity of platelet-specific markers, using a defined threshold to exclude non-platelet signals. For A-F, data is shown as mean ± SEM (n = 6). One-way ANOVA – Bonferroni was performed as a statistical analysis. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001 vs vehicle (DMSO 0.2%). For G-K, data are -presented as mean ± SEM (n = 3). One-way ANOVA with Bonferroni's post hoc test was used for statistical analysis. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 vs. vehicle (DMSO 0.2%).
W V Paraformaldehyde Pfa Nacalai Tesque, supplied by Nacalai, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pfa/paraformaldehyde/pmc13267569-196-23-26
Average 86 stars, based on 1 article reviews
w v paraformaldehyde pfa nacalai tesque - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier
pfa  (Thermo Fisher)
99
Thermo Fisher pfa
PSG6 inhibits platelet function without inducing cytotoxicity or impairing hemostasis . (A) Platelet cytotoxicity by LDH release. (B) Platelet apoptosis by Annexin-V (phosphatidylserine externalization). (C) Platelet viability by Calcein-AM. (D) Platelet aggregation induced with TRAP-6 at 5 μM of gentisic acid linked to TPP by different chain lengths. (E) P-Selectin expression (PE-CD62p). (F) Activated IIb/IIIa (FITC-Fibrinogen) (G) Representative image of clot retraction assay and clot weight after 2 h. <t>(H–I)</t> <t>PFA-200</t> closure times in collagen/ADP and collagen/epinephrine cartridges, respectively. Eptifibatide (EPT) 10 μM was used as a control for G–I. (J) Representative fluorescence microscopy images of thrombus formation on 3 different areas of collagen-coated channels under arterial shear conditions, showing vehicle (DMSO 0.2%) versus PSG6 at 10 μM. Thrombus coverage is expressed as the percentage of surface area occupied by fluorescently marked platelets. (K) Quantification of thrombus area based on fluorescence intensity of platelet-specific markers, using a defined threshold to exclude non-platelet signals. For A-F, data is shown as mean ± SEM (n = 6). One-way ANOVA – Bonferroni was performed as a statistical analysis. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001 vs vehicle (DMSO 0.2%). For G-K, data are -presented as mean ± SEM (n = 3). One-way ANOVA with Bonferroni's post hoc test was used for statistical analysis. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 vs. vehicle (DMSO 0.2%).
Pfa, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pfa/Triton+X-100/pm42315504-404-16-40
Average 99 stars, based on 1 article reviews
pfa - by Bioz Stars, 2026-09
99/100 stars
  Buy from Supplier
pfa pbs  (Thermo Fisher)
99
Thermo Fisher pfa pbs
PSG6 inhibits platelet function without inducing cytotoxicity or impairing hemostasis . (A) Platelet cytotoxicity by LDH release. (B) Platelet apoptosis by Annexin-V (phosphatidylserine externalization). (C) Platelet viability by Calcein-AM. (D) Platelet aggregation induced with TRAP-6 at 5 μM of gentisic acid linked to TPP by different chain lengths. (E) P-Selectin expression (PE-CD62p). (F) Activated IIb/IIIa (FITC-Fibrinogen) (G) Representative image of clot retraction assay and clot weight after 2 h. <t>(H–I)</t> <t>PFA-200</t> closure times in collagen/ADP and collagen/epinephrine cartridges, respectively. Eptifibatide (EPT) 10 μM was used as a control for G–I. (J) Representative fluorescence microscopy images of thrombus formation on 3 different areas of collagen-coated channels under arterial shear conditions, showing vehicle (DMSO 0.2%) versus PSG6 at 10 μM. Thrombus coverage is expressed as the percentage of surface area occupied by fluorescently marked platelets. (K) Quantification of thrombus area based on fluorescence intensity of platelet-specific markers, using a defined threshold to exclude non-platelet signals. For A-F, data is shown as mean ± SEM (n = 6). One-way ANOVA – Bonferroni was performed as a statistical analysis. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001 vs vehicle (DMSO 0.2%). For G-K, data are -presented as mean ± SEM (n = 3). One-way ANOVA with Bonferroni's post hoc test was used for statistical analysis. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 vs. vehicle (DMSO 0.2%).
Pfa Pbs, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pfa/Paraformaldehyde+Solution%2C+4%25+in+PBS/bio_rxiv__64898__2026__06__14__732116-294-13-14
Average 99 stars, based on 1 article reviews
pfa pbs - by Bioz Stars, 2026-09
99/100 stars
  Buy from Supplier

Image Search Results


PSG6 inhibits platelet function without inducing cytotoxicity or impairing hemostasis . (A) Platelet cytotoxicity by LDH release. (B) Platelet apoptosis by Annexin-V (phosphatidylserine externalization). (C) Platelet viability by Calcein-AM. (D) Platelet aggregation induced with TRAP-6 at 5 μM of gentisic acid linked to TPP by different chain lengths. (E) P-Selectin expression (PE-CD62p). (F) Activated IIb/IIIa (FITC-Fibrinogen) (G) Representative image of clot retraction assay and clot weight after 2 h. (H–I) PFA-200 closure times in collagen/ADP and collagen/epinephrine cartridges, respectively. Eptifibatide (EPT) 10 μM was used as a control for G–I. (J) Representative fluorescence microscopy images of thrombus formation on 3 different areas of collagen-coated channels under arterial shear conditions, showing vehicle (DMSO 0.2%) versus PSG6 at 10 μM. Thrombus coverage is expressed as the percentage of surface area occupied by fluorescently marked platelets. (K) Quantification of thrombus area based on fluorescence intensity of platelet-specific markers, using a defined threshold to exclude non-platelet signals. For A-F, data is shown as mean ± SEM (n = 6). One-way ANOVA – Bonferroni was performed as a statistical analysis. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001 vs vehicle (DMSO 0.2%). For G-K, data are -presented as mean ± SEM (n = 3). One-way ANOVA with Bonferroni's post hoc test was used for statistical analysis. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 vs. vehicle (DMSO 0.2%).

Journal: Redox Biology

Article Title: PSG6: A mitochondrially-targeted gentisic acid derivative exerts antiplatelet action via mitochondrial complex I inhibition

doi: 10.1016/j.redox.2026.104200

Figure Lengend Snippet: PSG6 inhibits platelet function without inducing cytotoxicity or impairing hemostasis . (A) Platelet cytotoxicity by LDH release. (B) Platelet apoptosis by Annexin-V (phosphatidylserine externalization). (C) Platelet viability by Calcein-AM. (D) Platelet aggregation induced with TRAP-6 at 5 μM of gentisic acid linked to TPP by different chain lengths. (E) P-Selectin expression (PE-CD62p). (F) Activated IIb/IIIa (FITC-Fibrinogen) (G) Representative image of clot retraction assay and clot weight after 2 h. (H–I) PFA-200 closure times in collagen/ADP and collagen/epinephrine cartridges, respectively. Eptifibatide (EPT) 10 μM was used as a control for G–I. (J) Representative fluorescence microscopy images of thrombus formation on 3 different areas of collagen-coated channels under arterial shear conditions, showing vehicle (DMSO 0.2%) versus PSG6 at 10 μM. Thrombus coverage is expressed as the percentage of surface area occupied by fluorescently marked platelets. (K) Quantification of thrombus area based on fluorescence intensity of platelet-specific markers, using a defined threshold to exclude non-platelet signals. For A-F, data is shown as mean ± SEM (n = 6). One-way ANOVA – Bonferroni was performed as a statistical analysis. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001 vs vehicle (DMSO 0.2%). For G-K, data are -presented as mean ± SEM (n = 3). One-way ANOVA with Bonferroni's post hoc test was used for statistical analysis. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 vs. vehicle (DMSO 0.2%).

Article Snippet: Subsequently, the sample was loaded into the Collagen/Epinephrine or Collagen/ADP cartridge, and the closure time was measured in the Innovance PFA-200 system (Siemens Healthcare Diagnostics Products, Munich, Germany).

Techniques: Expressing, Control, Fluorescence, Microscopy, Shear