pf 04856264 by alomone (Alomone Labs)


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Pf 04856264 By Alomone, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
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1) Product Images from "The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of erg -mediated K + Currents"
Article Title: The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of erg -mediated K + Currents
Journal: Biomedicines
doi: 10.3390/biomedicines10040780

Figure Legend Snippet: Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM PF-04856264. The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).
Techniques Used: Transferring