pf 04856264 by alomone  (Alomone Labs)


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    Alomone Labs pf 04856264 by alomone
    Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM <t>PF-04856264.</t> The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).
    Pf 04856264 By Alomone, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pf 04856264 by alomone/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    pf 04856264 by alomone - by Bioz Stars, 2023-02
    94/100 stars

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    1) Product Images from "The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of erg -mediated K + Currents"

    Article Title: The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of erg -mediated K + Currents

    Journal: Biomedicines

    doi: 10.3390/biomedicines10040780

    Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM PF-04856264. The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).
    Figure Legend Snippet: Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM PF-04856264. The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).

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    Alomone Labs pf 04856264 by alomone
    Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM <t>PF-04856264.</t> The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).
    Pf 04856264 By Alomone, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pf 04856264 by alomone/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    pf 04856264 by alomone - by Bioz Stars, 2023-02
    94/100 stars
    		  Buy from Supplier

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    Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM PF-04856264. The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).

    Journal: Biomedicines

    Article Title: The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of erg -mediated K + Currents

    doi: 10.3390/biomedicines10040780

    Figure Lengend Snippet: Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM PF-04856264. The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).

    Article Snippet: Diazoxide, tetraethylammonium chloride (TEA), and tetrodotoxin (TTX) were supplied by Sigma-Aldrich (Merck, Tainan, Taiwan), PF-04856264 by Alomone (Jerusalem, Israel), and PD118057 by Tocris (Bristol, UK).

    Techniques: Transferring