pc3 pip  (ATCC)

Journal: RNA nanomed

Article Title: RNA Nanoparticles Harboring Radioisotopes or Other Imaging Molecules for Spontaneous Tumor Targeting for Early Cancer Diagnosis

doi: 10.59566/isrnn.2025.0201d

Figure Lengend Snippet: Flow cytometry analysis of RNA nanoparticles (50 nM and 100 nM) binding to PC3 and PC3 PIP cells.

Article Snippet: PC3, PC3 PIP, and KB cells were obtained from American Type Culture Collection (ATCC).

Techniques: Flow Cytometry, Binding Assay

Journal: RNA nanomed

Article Title: RNA Nanoparticles Harboring Radioisotopes or Other Imaging Molecules for Spontaneous Tumor Targeting for Early Cancer Diagnosis

doi: 10.59566/isrnn.2025.0201d

Figure Lengend Snippet: Ex vivo fluorescent imaging of organs showing the distribution of SF5 3WJ nanoparticles in PC3 PIP xenograft bearing mice (T: tumor, H: heart, S: spleen, Lu: lung, K: kidney, and Lv: liver).

Article Snippet: PC3, PC3 PIP, and KB cells were obtained from American Type Culture Collection (ATCC).

Techniques: Ex Vivo, Imaging

Journal: RNA nanomed

Article Title: RNA Nanoparticles Harboring Radioisotopes or Other Imaging Molecules for Spontaneous Tumor Targeting for Early Cancer Diagnosis

doi: 10.59566/isrnn.2025.0201d

Figure Lengend Snippet: (Green arrows indicate the location of PC3 xenograft and the blue arrows indicate the bladder). Scale bar – 1 cm.

Article Snippet: PC3, PC3 PIP, and KB cells were obtained from American Type Culture Collection (ATCC).

Techniques:

Journal: ACS Omega

Article Title: Structure–Activity Relationships and Biological Insights into PSMA-617 and Its Derivatives with Modified Lipophilic Linker Regions

doi: 10.1021/acsomega.4c10142

Figure Lengend Snippet: Uptake of radiolabeled PSMA ligands in the spleen, kidney, and PC3-PIP tumor at 1, 2, and 24 h p.i. is presented for (A) [ 177 Lu]Lu-P17, (B) [ 177 Lu]Lu-P18, and (C) [ 177 Lu]Lu-PSMA-617. Data are average ± SD % IA/g ( n = 3).

Article Snippet: In vitro assays were performed using the sublines of the androgen-independent PC3 human PCa cell line, PSMA-positive (PSMA+) PC3-PIP and PSMA-negative (PSMA−) PC3-flu cells, purchased from Johns Hopkins University (Baltimore, MA, USA).

Techniques:

Journal: ACS Omega

Article Title: Structure–Activity Relationships and Biological Insights into PSMA-617 and Its Derivatives with Modified Lipophilic Linker Regions

doi: 10.1021/acsomega.4c10142

Figure Lengend Snippet: IC 50 Values a Determined via PSMA Enzyme and PSMA Cell-Based Assay

Article Snippet: In vitro assays were performed using the sublines of the androgen-independent PC3 human PCa cell line, PSMA-positive (PSMA+) PC3-PIP and PSMA-negative (PSMA−) PC3-flu cells, purchased from Johns Hopkins University (Baltimore, MA, USA).

Techniques: Cell Based Assay

Journal: ACS Omega

Article Title: Structure–Activity Relationships and Biological Insights into PSMA-617 and Its Derivatives with Modified Lipophilic Linker Regions

doi: 10.1021/acsomega.4c10142

Figure Lengend Snippet: Internalization Rates a Determined via PSMA Cell-Based Assay Using PC3-PIP Cells

Article Snippet: In vitro assays were performed using the sublines of the androgen-independent PC3 human PCa cell line, PSMA-positive (PSMA+) PC3-PIP and PSMA-negative (PSMA−) PC3-flu cells, purchased from Johns Hopkins University (Baltimore, MA, USA).

Techniques: Cell Based Assay, Binding Assay

Journal: ACS Omega

Article Title: Structure–Activity Relationships and Biological Insights into PSMA-617 and Its Derivatives with Modified Lipophilic Linker Regions

doi: 10.1021/acsomega.4c10142

Figure Lengend Snippet: Biodistribution a in PC3-PIP and PC3-flu Tumor-Bearing Balb/c Nude Mice at 1, 2, and 24 h p.i. of [ 177 Lu]Lu-P17

Article Snippet: In vitro assays were performed using the sublines of the androgen-independent PC3 human PCa cell line, PSMA-positive (PSMA+) PC3-PIP and PSMA-negative (PSMA−) PC3-flu cells, purchased from Johns Hopkins University (Baltimore, MA, USA).

Techniques:

Journal: ACS Omega

Article Title: Structure–Activity Relationships and Biological Insights into PSMA-617 and Its Derivatives with Modified Lipophilic Linker Regions

doi: 10.1021/acsomega.4c10142

Figure Lengend Snippet: Biodistribution a in PC3-PIP and PC3-flu Tumor-Bearing Balb/c Nude Mice at 1, 2, and 24 h p.i. of [ 177 Lu]Lu-P18

Article Snippet: In vitro assays were performed using the sublines of the androgen-independent PC3 human PCa cell line, PSMA-positive (PSMA+) PC3-PIP and PSMA-negative (PSMA−) PC3-flu cells, purchased from Johns Hopkins University (Baltimore, MA, USA).

Techniques:

Journal: ACS Omega

Article Title: Structure–Activity Relationships and Biological Insights into PSMA-617 and Its Derivatives with Modified Lipophilic Linker Regions

doi: 10.1021/acsomega.4c10142

Figure Lengend Snippet: Biodistribution a in PC3-PIP and PC3-flu Tumor-Bearing Balb/c Nude Mice at 1, 2, and 24 h p.i. of [ 177 Lu]Lu-PSMA-617

Article Snippet: In vitro assays were performed using the sublines of the androgen-independent PC3 human PCa cell line, PSMA-positive (PSMA+) PC3-PIP and PSMA-negative (PSMA−) PC3-flu cells, purchased from Johns Hopkins University (Baltimore, MA, USA).

Techniques: