Journal: International Journal of Medical Sciences

Article Title: Effects of Daehwang-Hwanglyoun-Sasim-Tang on brain injury and cognitive function in mice caused by bilateral common carotid artery stenosis

doi: 10.7150/ijms.77879

Figure Lengend Snippet: Effects of DHST treatment on changes in ERK (A and B), JNK (A and C), and Mn-SOD (D) in the bilateral common carotid artery stenosis (BCAS)-induced vascular dementia (VD) model mouse brain. Representative images and relative densitometry of western blot data for p-ERK, ERK, p-JNK, JNK, and β-actin in hippocampal brain tissues (n = 5 experiments). All data are expressed as means ± SD. # p < 0.05 vs. sham group, ## p < 0.01 vs. sham group, * p < 0.05 vs. BCAS control group. Abbreviations: BCAS, bilateral common carotid artery stenosis; DHST, Daehwang-Hwanglyoun-Sasim-Tang; Mn-SOD, manganese superoxide dismutase.

Article Snippet: The primary antibodies against c-Jun N-terminal kinase (JNK), phospho-JNK (p-JNK), protein kinase B (Akt), p-Akt, manganese superoxide dismutase (Mn-SOD), and β-actin were purchased from Cell Signaling Technology (Danvers, MA, USA).

Techniques: Western Blot