p her2 neu 1221  (Cell Signaling Technology Inc)


Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
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    Cell Signaling Technology Inc p her2 neu 1221
    P Her2 Neu 1221, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p her2 neu 1221/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    p her2 neu 1221 - by Bioz Stars, 2024-06
    86/100 stars

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    p her2 neu 1221  (Cell Signaling Technology Inc)


    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
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  • 86

    Structured Review

    Cell Signaling Technology Inc p her2 neu 1221
    P Her2 Neu 1221, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p her2 neu 1221/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    p her2 neu 1221 - by Bioz Stars, 2024-06
    86/100 stars

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    p her2 neu 1221  (Cell Signaling Technology Inc)


    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
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    Cell Signaling Technology Inc p her2 neu 1221
    Comparison of mean IC 50 values between <t>HER2-amplified</t> and -non-amplified cell lines. ( A ) Comparison of mean IC 50 values for each HER2-amplified and -non-amplified cell line run in triplicate. ( B ) Comparison of the overall mean IC 50 values for HER2-amplified and -non-amplified cell lines each represented in triplicate.
    P Her2 Neu 1221, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p her2 neu 1221/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    p her2 neu 1221 - by Bioz Stars, 2024-06
    86/100 stars

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    1) Product Images from "Afatinib demonstrates remarkable activity against HER2-amplified uterine serous endometrial cancer in vitro and in vivo"

    Article Title: Afatinib demonstrates remarkable activity against HER2-amplified uterine serous endometrial cancer in vitro and in vivo

    Journal: British Journal of Cancer

    doi: 10.1038/bjc.2014.519

    Comparison of mean IC 50 values between HER2-amplified and -non-amplified cell lines. ( A ) Comparison of mean IC 50 values for each HER2-amplified and -non-amplified cell line run in triplicate. ( B ) Comparison of the overall mean IC 50 values for HER2-amplified and -non-amplified cell lines each represented in triplicate.
    Figure Legend Snippet: Comparison of mean IC 50 values between HER2-amplified and -non-amplified cell lines. ( A ) Comparison of mean IC 50 values for each HER2-amplified and -non-amplified cell line run in triplicate. ( B ) Comparison of the overall mean IC 50 values for HER2-amplified and -non-amplified cell lines each represented in triplicate.

    Techniques Used: Amplification

    Comparison of mean fluorescence intensity (MFI) of ErbB1 in HER2-amplified vs -non-amplified cell lines. The figure depicts a comparison of the MFI of ErbB1 by direct staining as detected using flow cytometry between HER2-amplified and -non-amplified cell lines.
    Figure Legend Snippet: Comparison of mean fluorescence intensity (MFI) of ErbB1 in HER2-amplified vs -non-amplified cell lines. The figure depicts a comparison of the MFI of ErbB1 by direct staining as detected using flow cytometry between HER2-amplified and -non-amplified cell lines.

    Techniques Used: Fluorescence, Amplification, Staining, Flow Cytometry

    Representative changes in S6 phosphorylation with afatinib treatment HER2-amplified vs -non-amplified cell lines. Representative changes in phosphorylation of the transcription factor S6 after treatment with scalar amounts of afatinib in ( A ) HER2-amplified (ARK2) and ( B ) -non-amplified (ARK11) cell lines 8 h after treatment.
    Figure Legend Snippet: Representative changes in S6 phosphorylation with afatinib treatment HER2-amplified vs -non-amplified cell lines. Representative changes in phosphorylation of the transcription factor S6 after treatment with scalar amounts of afatinib in ( A ) HER2-amplified (ARK2) and ( B ) -non-amplified (ARK11) cell lines 8 h after treatment.

    Techniques Used: Amplification

    Comparison of mean fluorescence intensity (MFI) for phosphorylated HER2 and phosphorylated S6. Comparison of the MFI of phosphorylated HER2 ( A ) and phosphorylated S6 at 10 h ( B ) in HER2-amplified cell line ARK 2 after treatment with afatinib at a concentration of 5 n M (IC 50 ), 50 n M (human serum concentration after 24 h of 40 mg of afatinib by mouth), and 175 n M (human serum concentration after 28 days of 40 mg of afatinib by mouth daily).
    Figure Legend Snippet: Comparison of mean fluorescence intensity (MFI) for phosphorylated HER2 and phosphorylated S6. Comparison of the MFI of phosphorylated HER2 ( A ) and phosphorylated S6 at 10 h ( B ) in HER2-amplified cell line ARK 2 after treatment with afatinib at a concentration of 5 n M (IC 50 ), 50 n M (human serum concentration after 24 h of 40 mg of afatinib by mouth), and 175 n M (human serum concentration after 28 days of 40 mg of afatinib by mouth daily).

    Techniques Used: Fluorescence, Amplification, Concentration Assay

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    Cell Signaling Technology Inc p her2 neu 1221
    P Her2 Neu 1221, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p her2 neu 1221/product/Cell Signaling Technology Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    p her2 neu 1221 - by Bioz Stars, 2024-06
    86/100 stars
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