non optical ion torrent sequencer (Thermo Fisher)
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Name:
Ion Proton System
Description:
The Ion Proton System is the first benchtop sequencing system capable of human scale genome exome or transcriptome sequencing in a few hours with DNA to variants called in a single day The system combines semiconductor sequencing technology with natural biochemistry to directly translate chemical information into digital data By leveraging the exponential improvements in the semiconductor industry known as Moore s Law the Ion Proton Sequencing System provides an unprecedented level of scalability and flexibility to support a broad range of high throughput sequencing applications ranging from human scale genome to exome to transcriptome sequencing The system s use of the simplest natural sequencing chemistry eliminates the need for expensive optics and complex sequencing chemistries resulting in a highly affordable sequencing system to own and operate Real time direct electrical detection of sequencing combined with the enormous amount of computing power in both the Ion Proton Sequencer and Ion Proton Torrent Server enables generation of high quality sequencing results from DNA library to variants in a single day Features of the Ion Proton System • Fastest high throughput next generation sequencing workflow with the fastest sequencing run times of 2 4 hours on the Ion PI Chip • Highest number of complete sequencing runs per week with a simple and automated workflow when used with the Ion OneTouch 2 System • Simple semiconductor sequencing workflows with robust and simple hardware that can be relied upon no cameras no optics and no lasers • Scalable high throughput sequencing capabilities enabling up to 200 base single reads and flexible library options e g fragment gDNA targeted exome RNA • Small benchtop footprint and mounting capability with optional rack two Ion Proton systems per rack to deliver the only benchtop genome center • Low cost platform and attractively priced semiconductor chips and reagents for a range of applications • Proven Ion semiconductor sequencing requires no complex optics and employs natural nucleotides to deliver highly accurate variant detection uniformity of coverage and sensitivity to detect low frequency variants • Range of fast and simple library solutions and kits with low input requirements for a variety of applications such as genomic sequencing exome sequencing sequencing sets of genes and RNA sequencing • Complete end to end solution from base calls to variants with the Proton Torrent Server and Torrent Suite Software v3 0 • Simple and integrated tools for tertiary data analysis with Ion Reporter Software for DNA variation analysis across single paired or trio samples With the availability of the groundbreaking Ion Proton System rapid high throughput sequencing is finally accessible by all laboratories Affordable Sequencing For Nearly Every LabPrevious sequencing technologies have relied upon optical systems as bridges between the chemical and digital forms of sequence information These systems have added tremendous costs to sequencers relegating them to only the largest laboratories By eliminating the need for the optical system the Ion Proton System provides high throughput sequencing that is simpler faster more cost effective and more scalable than any other technology available With a benchtop footprint low cost sequencing reagents and a simple touchscreen user interface the Ion Proton System brings high throughput next generation sequencing to nearly every lab Ion Power PostLight Sequencing Produces Bits From BasesThe sequencing technology underlying the Ion Proton System exploits a well characterized biochemical process When a nucleotide is incorporated into a strand of DNA by a polymerase a hydrogen ion H is released as a byproduct This hydrogen ion carries a charge that the Proton System s ion sensor essentially the world s smallest solid state pH meter can detect As the sequencer floods the chip with one nucleotide after another any nucleotide added to a DNA template will be detected as a voltage change and the Ion Proton System will call the base If a nucleotide is not a match for a particular template no voltage change will be detected and no base will be called for that template Massively Parallel Sequencing On Your BenchA principal component of the Ion Proton System is the sequencing chip The Ion PI Chip incorporates an extremely dense array of 165 million micro machined wells married to our proprietary ion sensor Each well contains a different DNA template allowing massively parallel sequencing With the Ion PI Chip 165 million wells the Ion Proton System enables a range of high throughput genomic applications from human scale exome sequencing to whole transcriptome sequencing The Right Tool To Get Results Easily Reliably and QuicklyBecause it detects nucleotide incorporation without the use of light the Ion Proton System uses the simplest sequencing chemistry possible natural nucleotides There is no need for expensive and error prone modified bases enzymatic cascades chemiluminescence or fluorescence Direct detection also means the incorporation of each nucleotide is recorded in seconds As a result you can do an entire sequencing run typically in a few hours Services and Support Service and support plans comprehensive plans to maximize instrument performance and ensure availability of critical systems Qualification services document and ensure instrument is installed operating and performing to manufacturer s specifications Training courses for experimental design data analysis troubleshooting applications and instrument operation Bioinformatics tailored support for NGS informatics execution software use data analysis and downstream applications DataSafe Solution storage and back up strategy design hardware and support for all lab data
Catalog Number:
4476610
Price:
None
Category:
Instruments and Equipment
Applications:
DNA Sequencing|Epigenetic Sequencing|Fragment Analysis|Genotyping & Genomic Profiling|Ion Torrent™ Next-Generation Sequencing|Ion Torrent™ Systems & Accessories|Mitochondrial Sequencing|RNA Sequencing|SNP Genotyping by Fragment-Analysis|Sequencing|Small RNA & miRNA Sequencing|Methylation Analysis by Sequencing|Whole Genome Sequencing|Whole Transcriptome Sequencing|SNP Genotyping|Gene Expression Analysis & Genotyping|ChIP Sequencing|De Novo Sequencing|Gene Expression Profiling by Sequencing
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Structured Review
Thermo Fisher
non optical ion torrent sequencer
The Ion Proton System is the first benchtop sequencing system capable of human scale genome exome or transcriptome sequencing in a few hours with DNA to variants called in a single day The system combines semiconductor sequencing technology with natural biochemistry to directly translate chemical information into digital data By leveraging the exponential improvements in the semiconductor industry known as Moore s Law the Ion Proton Sequencing System provides an unprecedented level of scalability and flexibility to support a broad range of high throughput sequencing applications ranging from human scale genome to exome to transcriptome sequencing The system s use of the simplest natural sequencing chemistry eliminates the need for expensive optics and complex sequencing chemistries resulting in a highly affordable sequencing system to own and operate Real time direct electrical detection of sequencing combined with the enormous amount of computing power in both the Ion Proton Sequencer and Ion Proton Torrent Server enables generation of high quality sequencing results from DNA library to variants in a single day Features of the Ion Proton System • Fastest high throughput next generation sequencing workflow with the fastest sequencing run times of 2 4 hours on the Ion PI Chip • Highest number of complete sequencing runs per week with a simple and automated workflow when used with the Ion OneTouch 2 System • Simple semiconductor sequencing workflows with robust and simple hardware that can be relied upon no cameras no optics and no lasers • Scalable high throughput sequencing capabilities enabling up to 200 base single reads and flexible library options e g fragment gDNA targeted exome RNA • Small benchtop footprint and mounting capability with optional rack two Ion Proton systems per rack to deliver the only benchtop genome center • Low cost platform and attractively priced semiconductor chips and reagents for a range of applications • Proven Ion semiconductor sequencing requires no complex optics and employs natural nucleotides to deliver highly accurate variant detection uniformity of coverage and sensitivity to detect low frequency variants • Range of fast and simple library solutions and kits with low input requirements for a variety of applications such as genomic sequencing exome sequencing sequencing sets of genes and RNA sequencing • Complete end to end solution from base calls to variants with the Proton Torrent Server and Torrent Suite Software v3 0 • Simple and integrated tools for tertiary data analysis with Ion Reporter Software for DNA variation analysis across single paired or trio samples With the availability of the groundbreaking Ion Proton System rapid high throughput sequencing is finally accessible by all laboratories Affordable Sequencing For Nearly Every LabPrevious sequencing technologies have relied upon optical systems as bridges between the chemical and digital forms of sequence information These systems have added tremendous costs to sequencers relegating them to only the largest laboratories By eliminating the need for the optical system the Ion Proton System provides high throughput sequencing that is simpler faster more cost effective and more scalable than any other technology available With a benchtop footprint low cost sequencing reagents and a simple touchscreen user interface the Ion Proton System brings high throughput next generation sequencing to nearly every lab Ion Power PostLight Sequencing Produces Bits From BasesThe sequencing technology underlying the Ion Proton System exploits a well characterized biochemical process When a nucleotide is incorporated into a strand of DNA by a polymerase a hydrogen ion H is released as a byproduct This hydrogen ion carries a charge that the Proton System s ion sensor essentially the world s smallest solid state pH meter can detect As the sequencer floods the chip with one nucleotide after another any nucleotide added to a DNA template will be detected as a voltage change and the Ion Proton System will call the base If a nucleotide is not a match for a particular template no voltage change will be detected and no base will be called for that template Massively Parallel Sequencing On Your BenchA principal component of the Ion Proton System is the sequencing chip The Ion PI Chip incorporates an extremely dense array of 165 million micro machined wells married to our proprietary ion sensor Each well contains a different DNA template allowing massively parallel sequencing With the Ion PI Chip 165 million wells the Ion Proton System enables a range of high throughput genomic applications from human scale exome sequencing to whole transcriptome sequencing The Right Tool To Get Results Easily Reliably and QuicklyBecause it detects nucleotide incorporation without the use of light the Ion Proton System uses the simplest sequencing chemistry possible natural nucleotides There is no need for expensive and error prone modified bases enzymatic cascades chemiluminescence or fluorescence Direct detection also means the incorporation of each nucleotide is recorded in seconds As a result you can do an entire sequencing run typically in a few hours Services and Support Service and support plans comprehensive plans to maximize instrument performance and ensure availability of critical systems Qualification services document and ensure instrument is installed operating and performing to manufacturer s specifications Training courses for experimental design data analysis troubleshooting applications and instrument operation Bioinformatics tailored support for NGS informatics execution software use data analysis and downstream applications DataSafe Solution storage and back up strategy design hardware and support for all lab data
https://www.bioz.com/result/non optical ion torrent sequencer/product/Thermo Fisher
Average 97 stars, based on 1 article reviews
Price from $9.99 to $1999.99
The Ion Proton System is the first benchtop sequencing system capable of human scale genome exome or transcriptome sequencing in a few hours with DNA to variants called in a single day The system combines semiconductor sequencing technology with natural biochemistry to directly translate chemical information into digital data By leveraging the exponential improvements in the semiconductor industry known as Moore s Law the Ion Proton Sequencing System provides an unprecedented level of scalability and flexibility to support a broad range of high throughput sequencing applications ranging from human scale genome to exome to transcriptome sequencing The system s use of the simplest natural sequencing chemistry eliminates the need for expensive optics and complex sequencing chemistries resulting in a highly affordable sequencing system to own and operate Real time direct electrical detection of sequencing combined with the enormous amount of computing power in both the Ion Proton Sequencer and Ion Proton Torrent Server enables generation of high quality sequencing results from DNA library to variants in a single day Features of the Ion Proton System • Fastest high throughput next generation sequencing workflow with the fastest sequencing run times of 2 4 hours on the Ion PI Chip • Highest number of complete sequencing runs per week with a simple and automated workflow when used with the Ion OneTouch 2 System • Simple semiconductor sequencing workflows with robust and simple hardware that can be relied upon no cameras no optics and no lasers • Scalable high throughput sequencing capabilities enabling up to 200 base single reads and flexible library options e g fragment gDNA targeted exome RNA • Small benchtop footprint and mounting capability with optional rack two Ion Proton systems per rack to deliver the only benchtop genome center • Low cost platform and attractively priced semiconductor chips and reagents for a range of applications • Proven Ion semiconductor sequencing requires no complex optics and employs natural nucleotides to deliver highly accurate variant detection uniformity of coverage and sensitivity to detect low frequency variants • Range of fast and simple library solutions and kits with low input requirements for a variety of applications such as genomic sequencing exome sequencing sequencing sets of genes and RNA sequencing • Complete end to end solution from base calls to variants with the Proton Torrent Server and Torrent Suite Software v3 0 • Simple and integrated tools for tertiary data analysis with Ion Reporter Software for DNA variation analysis across single paired or trio samples With the availability of the groundbreaking Ion Proton System rapid high throughput sequencing is finally accessible by all laboratories Affordable Sequencing For Nearly Every LabPrevious sequencing technologies have relied upon optical systems as bridges between the chemical and digital forms of sequence information These systems have added tremendous costs to sequencers relegating them to only the largest laboratories By eliminating the need for the optical system the Ion Proton System provides high throughput sequencing that is simpler faster more cost effective and more scalable than any other technology available With a benchtop footprint low cost sequencing reagents and a simple touchscreen user interface the Ion Proton System brings high throughput next generation sequencing to nearly every lab Ion Power PostLight Sequencing Produces Bits From BasesThe sequencing technology underlying the Ion Proton System exploits a well characterized biochemical process When a nucleotide is incorporated into a strand of DNA by a polymerase a hydrogen ion H is released as a byproduct This hydrogen ion carries a charge that the Proton System s ion sensor essentially the world s smallest solid state pH meter can detect As the sequencer floods the chip with one nucleotide after another any nucleotide added to a DNA template will be detected as a voltage change and the Ion Proton System will call the base If a nucleotide is not a match for a particular template no voltage change will be detected and no base will be called for that template Massively Parallel Sequencing On Your BenchA principal component of the Ion Proton System is the sequencing chip The Ion PI Chip incorporates an extremely dense array of 165 million micro machined wells married to our proprietary ion sensor Each well contains a different DNA template allowing massively parallel sequencing With the Ion PI Chip 165 million wells the Ion Proton System enables a range of high throughput genomic applications from human scale exome sequencing to whole transcriptome sequencing The Right Tool To Get Results Easily Reliably and QuicklyBecause it detects nucleotide incorporation without the use of light the Ion Proton System uses the simplest sequencing chemistry possible natural nucleotides There is no need for expensive and error prone modified bases enzymatic cascades chemiluminescence or fluorescence Direct detection also means the incorporation of each nucleotide is recorded in seconds As a result you can do an entire sequencing run typically in a few hours Services and Support Service and support plans comprehensive plans to maximize instrument performance and ensure availability of critical systems Qualification services document and ensure instrument is installed operating and performing to manufacturer s specifications Training courses for experimental design data analysis troubleshooting applications and instrument operation Bioinformatics tailored support for NGS informatics execution software use data analysis and downstream applications DataSafe Solution storage and back up strategy design hardware and support for all lab data
https://www.bioz.com/result/non optical ion torrent sequencer/product/Thermo Fisher
Average 97 stars, based on 1 article reviews
Price from $9.99 to $1999.99
non optical ion torrent sequencer - by Bioz Stars,
2021-04
97/100 stars
Images
1) Product Images from "Semiconductor-based sequencing of genome-wide DNA methylation states"
Article Title: Semiconductor-based sequencing of genome-wide DNA methylation states
Journal: Epigenetics
doi: 10.1080/15592294.2014.1003747
Figure Legend Snippet: Scalability of Ion Torrent-compatible MeDIP-Seq protocol. (a) Global 5-methylcytosine (5mC) content measured as a percentage of the genome in DNA from WT and DKO cells determined by an ELISA assay. (b) Number of peaks identified by MACS v2.1.0 software 64 from MeDIP-Seq data in WT and DKO cells. (c) Sequence coverage of genome-wide CpGs for WT and DKO cells on the Ion Torrent Proton sequencer calculated using MEDIPS v1.14.0 software. 39 Pie charts illustrate the fraction of CpGs covered by the indicated reads according to their fold-coverage in relation to the total genomic CpG content from MeDIP-Seq libraries of the indicated sample sequenced on the Proton with the total number of non-redundant mapped reads in parentheses. (d) Sequence coverage of genome-wide CpGs for WT and DKO cells in MeDIP-Seq on the Ion Torrent PGM sequencer. Data displayed as in c . (e) Scaled chromosomal view of the 5mC MeDIP-Seq enrichment of methylation over the MX1 gene in WT and DKO cells sequenced on the 2 different Ion Torrent sequencers as indicated. MeDIP-Seq data are displayed as RPM (Reads Per Million mapped reads) below the RefSeq annotation of the gene (blue lines). Methylation enrichment is displayed in gray, with red vertical lines corresponding to areas containing CpGs. Chromosome position and gene orientation are displayed.
Techniques Used: Methylated DNA Immunoprecipitation, Enzyme-linked Immunosorbent Assay, Magnetic Cell Separation, Software, Sequencing, Genome Wide, Methylation
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