Nmda Receptor 2b Glun2b D15b3 Rabbit Mab, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1) Product Images from "Effect of Ginkgo Biloba Extract on N-Methyl-D-Aspartic Acid Receptor Subunit 2B Expression in a Salicylate-Induced Ototoxicity Model"
Article Title: Effect of Ginkgo Biloba Extract on N-Methyl-D-Aspartic Acid Receptor Subunit 2B Expression in a Salicylate-Induced Ototoxicity Model
Journal: Clinical and Experimental Otorhinolaryngology
Figure Legend Snippet: Western blot analysis of the N-methyl-D-aspartate receptor (NMDA-R) subunit 2B (GluN2B) in the inferior colliculus (IC). (A) The expression of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) protein among the four groups. (B) The expression of the GluN2B protein was significantly higher in the SS group compared to the control group. In addition, GluN2B protein expression was significantly lower in the EGb+SS group, as compared to the SS group. (C) Relative protein expression of GluN2B in the IC. The expression of GluN2B protein was significantly higher in the SS group and EGb+SS group compared to the control and EGb groups. Notably, the expression of GluN2B protein was significantly decreased in EGb+SS group following EGb pretreatment compared to that in SS group. SS, sodium salicylate; EGb, EGb 761 Ginkgo biloba extract. *P
Techniques Used: Western Blot, Expressing
Figure Legend Snippet: The N-methyl-D-aspartate receptor (NMDA-R) subunit 2B (GluN2B) immunohistochemistry in the inferior colliculus (×200 magnification). (A) The control group showed no GluN2B immunoreactivity. (B) Brain samples from the EGb-treated group also showed negative GluN2B staining. (C) In the SS-treated group, strong immunoreactivity was detected in neuronal cells (arrow) along with some scattered glial cell immunoreactivity (arrowhead). (D) GluN2B staining vanished in the EGb+SS group, with only weak focal immunoreactivity. EGb, EGb 761 Ginkgo biloba extract; SS, sodium salicylate.
Techniques Used: Immunohistochemistry, Staining