n m charybdotoxin  (Alomone Labs)

Journal:

Article Title: Effects of halothane on the membrane potential in skeletal muscle of the frog

doi: 10.1038/sj.bjp.0703330

Figure Lengend Snippet: Effect of ryanodine, charybdotoxin (CTX) or glibenclamide on frog sartorius muscle resting membrane potential (Vm) after prior halothane 3%-treatment

Article Snippet: In some experiments, the following inhibitors were used: 0.6 μ M tetrodotoxin (TTX, Sankyo, Tokyo, Japan) to entirely inhibit the Na + current ( Pater & Sauviat, 1987 ), 10 m M tetraethylammonium (TEA, Sigma Aldricht, Saint Quentin Fallavier, France) to completely suppress the delayed outward K + current ( Pater & Sauviat, 1987 ), 1 m M 4-acetamido-4′-isothiocyanatostilbene 2,2′disulphonic acid (SITS, Sigma) to suppress Cl − currents, 10 μ M ryanodine (Sigma) to inhibit the Ca 2+ release from the SR ( Nasri-Sebdani et al ., 1990 ), 10 n M charybdotoxin (CTX, Alomone Labs, Jerusalem, Israel) to block large conductance Ca 2+ -activated K + (BK Ca ) channels ( Garcia et al ., 1995 ; Miller, 1995 ); 10 μ M glibenclamide (Hoechst Pharmaceuticals, Hounslow, U.K.) to inhibit the ATP-dependent K + (K ATP ) channels ( Sauviat et al ., 1991 ).

Techniques:

Journal:

Article Title: Effects of halothane on the membrane potential in skeletal muscle of the frog

doi: 10.1038/sj.bjp.0703330

Figure Lengend Snippet: Effect of halothane 3% on the resting membrane potential (Vm) of frog sartorius muscle after prior ryanodine, charybdotoxin (CTX) or glibenclamide treatment

Article Snippet: In some experiments, the following inhibitors were used: 0.6 μ M tetrodotoxin (TTX, Sankyo, Tokyo, Japan) to entirely inhibit the Na + current ( Pater & Sauviat, 1987 ), 10 m M tetraethylammonium (TEA, Sigma Aldricht, Saint Quentin Fallavier, France) to completely suppress the delayed outward K + current ( Pater & Sauviat, 1987 ), 1 m M 4-acetamido-4′-isothiocyanatostilbene 2,2′disulphonic acid (SITS, Sigma) to suppress Cl − currents, 10 μ M ryanodine (Sigma) to inhibit the Ca 2+ release from the SR ( Nasri-Sebdani et al ., 1990 ), 10 n M charybdotoxin (CTX, Alomone Labs, Jerusalem, Israel) to block large conductance Ca 2+ -activated K + (BK Ca ) channels ( Garcia et al ., 1995 ; Miller, 1995 ); 10 μ M glibenclamide (Hoechst Pharmaceuticals, Hounslow, U.K.) to inhibit the ATP-dependent K + (K ATP ) channels ( Sauviat et al ., 1991 ).

Techniques: