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mya 116  (Norian Corporation)

 
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    Norian Corporation mya 116
    Mya 116, supplied by Norian Corporation, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Overview of the PK/PD study setup. Observed data and interventions are depicted against time. Dotted lines, start of posaconazole therapy in the treatment and prophylaxis groups (time the first dose was applied); dashed lines, time of inoculation with 1 × 108 conidia of A. fumigatus; black connected dots, GMI values; gray connected dots, posaconazole plasma concentrations.

    Journal: Antimicrobial Agents and Chemotherapy

    Article Title: Pharmacodynamics of Posaconazole in Experimental Invasive Pulmonary Aspergillosis: Utility of Serum Galactomannan as a Dynamic Endpoint of Antifungal Efficacy

    doi: 10.1128/AAC.01574-20

    Figure Lengend Snippet: Overview of the PK/PD study setup. Observed data and interventions are depicted against time. Dotted lines, start of posaconazole therapy in the treatment and prophylaxis groups (time the first dose was applied); dashed lines, time of inoculation with 1 × 108 conidia of A. fumigatus; black connected dots, GMI values; gray connected dots, posaconazole plasma concentrations.

    Article Snippet: Aspergillus fumigatus (NIH isolate 4215 [ATCC MYA1163]) obtained from a fatal case of pulmonary aspergillosis was used in all experiments.

    Techniques:

    Strains used in this work a

    Journal:

    Article Title: Multiple Catalase Genes Are Differentially Regulated in Aspergillus nidulans

    doi: 10.1128/JB.183.4.1434-1440.2001

    Figure Lengend Snippet: Strains used in this work a

    Article Snippet: To disrupt the catC gene, strain RMS011 was transformed with plasmid pLK20 by using standard techniques ( 46 ). table ft1 table-wrap mode="anchored" t5 TABLE 1 caption a7 Strain Genotype Reference or source b FGSC26 biA1 veA1 FGSC RMS011 pabaA1 yA2 ΔargB :: trpCΔB veA1 trpC801 36 CLK20 biA1 ΔcatA :: argBΔA metG1 ΔcatB :: argBΔB veA1 Progeny from cross TRN1 × CLK15 (this work) (FGSC strain A1055 and ATCC MYA-116) TLK61 pabaA1 yA2 ΔcatC :: argBΔC ΔargB :: trpCΔB trpC801 veA1 Obtained by transforming strain RMS011 with linear pLK20 (this work) TLK12 pabaA1 yA2 ΔargB :: trpCΔB ΔcatB :: argBΔB trpC801 veA1 23 (FGSC strain A1054 and ATCC MYA-118) CLK35 pabaA1 yA2 biA1 ΔcatC :: argBΔC ΔcatA :: argBΔA ΔcatB :: argBΔB veA1 Progeny from cross CLK20 × TLK61 (this work) CLK14 biA1 ΔcatA :: argBΔA metG1 ΔcatB :: argBΔB veA1 Progeny from cross CLK12 × TLK12 (this work) CLK15 biA1 metG1 ΔcatB :: argBΔB veA1 Progeny from cross CLK12 × TLK12 (this work) RYC17 ΔargB :: trpCΔB ΔcatA :: argB veA1 Partial genotype 7 RYC16 ΔargB :: trpCΔB ΔcatA :: argB ΔcatB :: argB veA1 Partial genotype 7 CLK36 pabaA1 biA1 ΔcatC :: argBΔC ΔcatA :: argBΔA metG1 ΔcatB :: argBΔB veA1 Progeny from cross CLK20 × TLK61 (this work) Open in a separate window a To obtain triple catA catB catC mutants, strains CLK20 and TLK61 were crossed.

    Techniques: