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custom-designed multiplex array sequenom massarray iplex gold  (Sequenom)

 
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    Sequenom custom-designed multiplex array sequenom massarray iplex gold
    Custom Designed Multiplex Array Sequenom Massarray Iplex Gold, supplied by Sequenom, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/multiplex+massarray+design/sequenom+massarray/pm34015137-70-20-22
    Average 90 stars, based on 1 article reviews
    custom-designed multiplex array sequenom massarray iplex gold - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Multiplex Assay:

    Article Title: Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers
    Article Snippet: .. Primer extension-based assays with a multiplex design, such as the Sequenom MassARRAY system, detect multiple hotspots in a single reaction while retaining an analytic sensitivity of 5% mutant alleles or less. ..

    Article Title: Clinical mutational profiling of 1006 lung cancers by next generation sequencing
    Article Snippet: .. Primer extension-based assays with a multiplex design, such as the Sequenom MassARRAY system, detect multiple hotspots within a panel of genes including EGFR in a single reaction while retaining an analytic sensitivity of 5% or less VAF [ , ]. ..

    Article Title: Non-p.V600E BRAF Mutations Are Common Using a More Sensitive and Broad Detection Tool
    Article Snippet: .. Primer extension-based assays with a multiplex design, such as the Sequenom MassARRAY system (Sequenom, San Diego, CA) or the multiplex SNaPshot assay, detect multiple hotspots in a single reaction while also retaining an analytic sensitivity of 5% mutant alleles or less.4,9,36 Previous validation processes by others and by us have shown that NGS platforms are sufficiently robust for clinical detection of BRAF mutations.30,45-47 In this study, an NGS platform using an AmpliSeq panel and the PGM demonstrated an analytic sensitivity to detect specimens with 1% to 2% p.V600E mutations in an LN with scant subscapular metastasis and in an LN with an infiltrative metastasis, as well as a broad reportable range to identify uncommon mutations in both exons 11 and 15. ..

    Article Title: SERPINE2 rs16865421 polymorphism is associated with a lower risk of chronic obstructive pulmonary disease in the Uygur population: A case-control study.
    Article Snippet: Background: To investigate the relationship between 7 polymorphisms of the serine protease inhibitor-2 (SERPINE2) gene and the risk of chronic obstructive pulmonary disease (COPD) in a Uygur population by a case-control study.. Methods: A total of 440 Uygur patients with COPD were included in the patient group, and 384 healthy individuals were recruited in the matched control group.. Data on demographic variables, smoking status, occupational dust exposure history, and living conditions were collected.

    Article Title: Validation of genetic modifiers for Duchenne muscular dystrophy: a multicentre study assessing SPP1 and LTBP4 variants
    Article Snippet: To assay SNPs rs2303729, rs1131620, rs1051303 and rs10880, we used the Sequenom MassARRAY platform (Sequenom Inc, San Diego, California, USA) according to manufacturer's protocols, except for the PCR cycling protocol, which was performed as a step-down protocol (see online supplementary methods). .. Multiplex genotyping assays were designed using Sequenom MassARRAY Assay Design Suite, V.1.0 (Sequenom Inc). ..

    Article Title: Identification of regulatory variants associated with genetic susceptibility to meningococcal disease
    Article Snippet: .. Finally, 42 SNPs were selected for validation and submitted to design a custom Sequenom Multiplex MassArray assay. ..

    Mutagenesis:

    Article Title: Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers
    Article Snippet: .. Primer extension-based assays with a multiplex design, such as the Sequenom MassARRAY system, detect multiple hotspots in a single reaction while retaining an analytic sensitivity of 5% mutant alleles or less. ..

    Article Title: Non-p.V600E BRAF Mutations Are Common Using a More Sensitive and Broad Detection Tool
    Article Snippet: .. Primer extension-based assays with a multiplex design, such as the Sequenom MassARRAY system (Sequenom, San Diego, CA) or the multiplex SNaPshot assay, detect multiple hotspots in a single reaction while also retaining an analytic sensitivity of 5% mutant alleles or less.4,9,36 Previous validation processes by others and by us have shown that NGS platforms are sufficiently robust for clinical detection of BRAF mutations.30,45-47 In this study, an NGS platform using an AmpliSeq panel and the PGM demonstrated an analytic sensitivity to detect specimens with 1% to 2% p.V600E mutations in an LN with scant subscapular metastasis and in an LN with an infiltrative metastasis, as well as a broad reportable range to identify uncommon mutations in both exons 11 and 15. ..

    other:

    Article Title: Genetic polymorphisms of pharmacogenomic VIP variants in the Lisu population of southwestern China
    Article Snippet: [ , ] Multiplex SNPs were designed by Sequenom MassARRAY Assay Design 3.0 software (San Diego, CA).

    Article Title: Genetic polymorphisms of pharmacogenomic VIP variants in the Lisu population of southwestern China
    Article Snippet: [14,15] Multiplex SNPs were designed by Sequenom MassARRAY Assay Design 3.0 software (San Diego, CA).

    Biomarker Discovery:

    Article Title: Non-p.V600E BRAF Mutations Are Common Using a More Sensitive and Broad Detection Tool
    Article Snippet: .. Primer extension-based assays with a multiplex design, such as the Sequenom MassARRAY system (Sequenom, San Diego, CA) or the multiplex SNaPshot assay, detect multiple hotspots in a single reaction while also retaining an analytic sensitivity of 5% mutant alleles or less.4,9,36 Previous validation processes by others and by us have shown that NGS platforms are sufficiently robust for clinical detection of BRAF mutations.30,45-47 In this study, an NGS platform using an AmpliSeq panel and the PGM demonstrated an analytic sensitivity to detect specimens with 1% to 2% p.V600E mutations in an LN with scant subscapular metastasis and in an LN with an infiltrative metastasis, as well as a broad reportable range to identify uncommon mutations in both exons 11 and 15. ..

    Article Title: Identification of regulatory variants associated with genetic susceptibility to meningococcal disease
    Article Snippet: .. Finally, 42 SNPs were selected for validation and submitted to design a custom Sequenom Multiplex MassArray assay. ..

    Next-Generation Sequencing:

    Article Title: Non-p.V600E BRAF Mutations Are Common Using a More Sensitive and Broad Detection Tool
    Article Snippet: .. Primer extension-based assays with a multiplex design, such as the Sequenom MassARRAY system (Sequenom, San Diego, CA) or the multiplex SNaPshot assay, detect multiple hotspots in a single reaction while also retaining an analytic sensitivity of 5% mutant alleles or less.4,9,36 Previous validation processes by others and by us have shown that NGS platforms are sufficiently robust for clinical detection of BRAF mutations.30,45-47 In this study, an NGS platform using an AmpliSeq panel and the PGM demonstrated an analytic sensitivity to detect specimens with 1% to 2% p.V600E mutations in an LN with scant subscapular metastasis and in an LN with an infiltrative metastasis, as well as a broad reportable range to identify uncommon mutations in both exons 11 and 15. ..

    Polymerase Chain Reaction:

    Article Title: SERPINE2 rs16865421 polymorphism is associated with a lower risk of chronic obstructive pulmonary disease in the Uygur population: A case-control study.
    Article Snippet: Background: To investigate the relationship between 7 polymorphisms of the serine protease inhibitor-2 (SERPINE2) gene and the risk of chronic obstructive pulmonary disease (COPD) in a Uygur population by a case-control study.. Methods: A total of 440 Uygur patients with COPD were included in the patient group, and 384 healthy individuals were recruited in the matched control group.. Data on demographic variables, smoking status, occupational dust exposure history, and living conditions were collected.

    Synthesized:

    Article Title: SERPINE2 rs16865421 polymorphism is associated with a lower risk of chronic obstructive pulmonary disease in the Uygur population: A case-control study.
    Article Snippet: Background: To investigate the relationship between 7 polymorphisms of the serine protease inhibitor-2 (SERPINE2) gene and the risk of chronic obstructive pulmonary disease (COPD) in a Uygur population by a case-control study.. Methods: A total of 440 Uygur patients with COPD were included in the patient group, and 384 healthy individuals were recruited in the matched control group.. Data on demographic variables, smoking status, occupational dust exposure history, and living conditions were collected.

    Software:

    Article Title: SERPINE2 rs16865421 polymorphism is associated with a lower risk of chronic obstructive pulmonary disease in the Uygur population: A case-control study.
    Article Snippet: Background: To investigate the relationship between 7 polymorphisms of the serine protease inhibitor-2 (SERPINE2) gene and the risk of chronic obstructive pulmonary disease (COPD) in a Uygur population by a case-control study.. Methods: A total of 440 Uygur patients with COPD were included in the patient group, and 384 healthy individuals were recruited in the matched control group.. Data on demographic variables, smoking status, occupational dust exposure history, and living conditions were collected.



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    Associations of PIK3CG tagging SNPs with plasma lipid concentrations (N OGTT = 2,016).
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    Image Search Results


    Associations of PIK3CG tagging SNPs with plasma lipid concentrations (N OGTT = 2,016).

    Journal: PLoS ONE

    Article Title: Variation in the Phosphoinositide 3-Kinase Gamma Gene Affects Plasma HDL-Cholesterol without Modification of Metabolic or Inflammatory Markers

    doi: 10.1371/journal.pone.0144494

    Figure Lengend Snippet: Associations of PIK3CG tagging SNPs with plasma lipid concentrations (N OGTT = 2,016).

    Article Snippet: SNPs rs849405, rs2037718, and rs10216210 resisted massARRAY multiplex assay design and were, therefore, genotyped by allelic discrimination using commercial TaqMan assays (Applied Biosystems, Foster City, CA, USA).

    Techniques: Clinical Proteomics