mouse monoclonal anti kchip2  (NeuroMab)

 
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    NeuroMab mouse monoclonal anti kchip2
    Mouse Monoclonal Anti Kchip2, supplied by NeuroMab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    mouse monoclonal anti kchip2  (NeuroMab)

     
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    NeuroMab mouse monoclonal anti kchip2
    (A, B) Kv4.2 protein (A) and mRNA levels (B) are significantly reduced in Kv4.2HET mice compared with WT control (unpaired t-tests, WT: n=11, HET: n=12; A: t(21)=7.4, *p<0.0001; B: t(21)=8.3, *p<0.0001). (C) In contrast, Kv4.3 protein levels were unchanged (unpaired t-test, WT: n=11, HET: n=12; t(21)=1.1, p=0.286). (D-I) Of all tested auxiliary subunits of the Kv4.2 complex, only KChIP3 (D,F) was significantly reduced, whereas DPP6 (E,F), <t>KChIP2</t> (G,I) and DPP10 (H,I) were unchanged (D: unpaired t-test, n=11, t(20)=2.97, p=0.008; E: unpaired t-test, n=11, t(20)=1.67, p=0.11; G: Mann Whitney test, WT: n=11, HET: n=12, p=0.83; H: Mann Whitney test, WT: n=11, HET: n=12, p=0.79). Example Western Blots are shown on top in A and C, as well as in F for D and E, and in I for G and H. An additional example of western blots shown in F is shown in Fig. S1A. DPP6 and KChIP3 were either normalized to Akt or βActin, which did not differ between genotypes (Fig. S1B). Error bars represent SEM.
    Mouse Monoclonal Anti Kchip2, supplied by NeuroMab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal anti kchip2/product/NeuroMab
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    mouse monoclonal anti kchip2 - by Bioz Stars, 2023-02
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    1) Product Images from "The potassium channel Kv4.2 regulates dendritic spine morphology, electroencephalographic characteristics and seizure susceptibility in mice"

    Article Title: The potassium channel Kv4.2 regulates dendritic spine morphology, electroencephalographic characteristics and seizure susceptibility in mice

    Journal: Experimental neurology

    doi: 10.1016/j.expneurol.2020.113437

    (A, B) Kv4.2 protein (A) and mRNA levels (B) are significantly reduced in Kv4.2HET mice compared with WT control (unpaired t-tests, WT: n=11, HET: n=12; A: t(21)=7.4, *p<0.0001; B: t(21)=8.3, *p<0.0001). (C) In contrast, Kv4.3 protein levels were unchanged (unpaired t-test, WT: n=11, HET: n=12; t(21)=1.1, p=0.286). (D-I) Of all tested auxiliary subunits of the Kv4.2 complex, only KChIP3 (D,F) was significantly reduced, whereas DPP6 (E,F), KChIP2 (G,I) and DPP10 (H,I) were unchanged (D: unpaired t-test, n=11, t(20)=2.97, p=0.008; E: unpaired t-test, n=11, t(20)=1.67, p=0.11; G: Mann Whitney test, WT: n=11, HET: n=12, p=0.83; H: Mann Whitney test, WT: n=11, HET: n=12, p=0.79). Example Western Blots are shown on top in A and C, as well as in F for D and E, and in I for G and H. An additional example of western blots shown in F is shown in Fig. S1A. DPP6 and KChIP3 were either normalized to Akt or βActin, which did not differ between genotypes (Fig. S1B). Error bars represent SEM.
    Figure Legend Snippet: (A, B) Kv4.2 protein (A) and mRNA levels (B) are significantly reduced in Kv4.2HET mice compared with WT control (unpaired t-tests, WT: n=11, HET: n=12; A: t(21)=7.4, *p<0.0001; B: t(21)=8.3, *p<0.0001). (C) In contrast, Kv4.3 protein levels were unchanged (unpaired t-test, WT: n=11, HET: n=12; t(21)=1.1, p=0.286). (D-I) Of all tested auxiliary subunits of the Kv4.2 complex, only KChIP3 (D,F) was significantly reduced, whereas DPP6 (E,F), KChIP2 (G,I) and DPP10 (H,I) were unchanged (D: unpaired t-test, n=11, t(20)=2.97, p=0.008; E: unpaired t-test, n=11, t(20)=1.67, p=0.11; G: Mann Whitney test, WT: n=11, HET: n=12, p=0.83; H: Mann Whitney test, WT: n=11, HET: n=12, p=0.79). Example Western Blots are shown on top in A and C, as well as in F for D and E, and in I for G and H. An additional example of western blots shown in F is shown in Fig. S1A. DPP6 and KChIP3 were either normalized to Akt or βActin, which did not differ between genotypes (Fig. S1B). Error bars represent SEM.

    Techniques Used: MANN-WHITNEY, Western Blot

    mouse monoclonal anti kchip2  (NeuroMab)

     
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    NeuroMab mouse monoclonal anti kchip2
    (A, B) Kv4.2 protein (A) and mRNA levels (B) are significantly reduced in Kv4.2HET mice compared with WT control (unpaired t-tests, WT: n=11, HET: n=12; A: t(21)=7.4, *p<0.0001; B: t(21)=8.3, *p<0.0001). (C) In contrast, Kv4.3 protein levels were unchanged (unpaired t-test, WT: n=11, HET: n=12; t(21)=1.1, p=0.286). (D-I) Of all tested auxiliary subunits of the Kv4.2 complex, only KChIP3 (D,F) was significantly reduced, whereas DPP6 (E,F), <t>KChIP2</t> (G,I) and DPP10 (H,I) were unchanged (D: unpaired t-test, n=11, t(20)=2.97, p=0.008; E: unpaired t-test, n=11, t(20)=1.67, p=0.11; G: Mann Whitney test, WT: n=11, HET: n=12, p=0.83; H: Mann Whitney test, WT: n=11, HET: n=12, p=0.79). Example Western Blots are shown on top in A and C, as well as in F for D and E, and in I for G and H. An additional example of western blots shown in F is shown in Fig. S1A. DPP6 and KChIP3 were either normalized to Akt or βActin, which did not differ between genotypes (Fig. S1B). Error bars represent SEM.
    Mouse Monoclonal Anti Kchip2, supplied by NeuroMab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal anti kchip2/product/NeuroMab
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    mouse monoclonal anti kchip2 - by Bioz Stars, 2023-02
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    1) Product Images from "The potassium channel Kv4.2 regulates dendritic spine morphology, electroencephalographic characteristics and seizure susceptibility in mice"

    Article Title: The potassium channel Kv4.2 regulates dendritic spine morphology, electroencephalographic characteristics and seizure susceptibility in mice

    Journal: Experimental neurology

    doi: 10.1016/j.expneurol.2020.113437

    (A, B) Kv4.2 protein (A) and mRNA levels (B) are significantly reduced in Kv4.2HET mice compared with WT control (unpaired t-tests, WT: n=11, HET: n=12; A: t(21)=7.4, *p<0.0001; B: t(21)=8.3, *p<0.0001). (C) In contrast, Kv4.3 protein levels were unchanged (unpaired t-test, WT: n=11, HET: n=12; t(21)=1.1, p=0.286). (D-I) Of all tested auxiliary subunits of the Kv4.2 complex, only KChIP3 (D,F) was significantly reduced, whereas DPP6 (E,F), KChIP2 (G,I) and DPP10 (H,I) were unchanged (D: unpaired t-test, n=11, t(20)=2.97, p=0.008; E: unpaired t-test, n=11, t(20)=1.67, p=0.11; G: Mann Whitney test, WT: n=11, HET: n=12, p=0.83; H: Mann Whitney test, WT: n=11, HET: n=12, p=0.79). Example Western Blots are shown on top in A and C, as well as in F for D and E, and in I for G and H. An additional example of western blots shown in F is shown in Fig. S1A. DPP6 and KChIP3 were either normalized to Akt or βActin, which did not differ between genotypes (Fig. S1B). Error bars represent SEM.
    Figure Legend Snippet: (A, B) Kv4.2 protein (A) and mRNA levels (B) are significantly reduced in Kv4.2HET mice compared with WT control (unpaired t-tests, WT: n=11, HET: n=12; A: t(21)=7.4, *p<0.0001; B: t(21)=8.3, *p<0.0001). (C) In contrast, Kv4.3 protein levels were unchanged (unpaired t-test, WT: n=11, HET: n=12; t(21)=1.1, p=0.286). (D-I) Of all tested auxiliary subunits of the Kv4.2 complex, only KChIP3 (D,F) was significantly reduced, whereas DPP6 (E,F), KChIP2 (G,I) and DPP10 (H,I) were unchanged (D: unpaired t-test, n=11, t(20)=2.97, p=0.008; E: unpaired t-test, n=11, t(20)=1.67, p=0.11; G: Mann Whitney test, WT: n=11, HET: n=12, p=0.83; H: Mann Whitney test, WT: n=11, HET: n=12, p=0.79). Example Western Blots are shown on top in A and C, as well as in F for D and E, and in I for G and H. An additional example of western blots shown in F is shown in Fig. S1A. DPP6 and KChIP3 were either normalized to Akt or βActin, which did not differ between genotypes (Fig. S1B). Error bars represent SEM.

    Techniques Used: MANN-WHITNEY, Western Blot

    mouse monoclonal anti kchip2  (NeuroMab)

     
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    NeuroMab mouse monoclonal anti kchip2
    The expression of Kv4.3 and <t>KChIP2</t> was unchanged after 25-min ischemia. (A & B) In contrast to Kv4.2, no obvious decrease of immunoreactivity for other somatodendritic IA channel subunits, Kv4.3 (A) and KChIP2 (B), was noticed in the brain of either non-seizure and seizure rats at 1 day after ischemia. (C & D) Western blotting showing that Kv4.3 and <t>KChIP2</t> <t>protein</t> levels remained unchanged in the hippocampus (C) and cortex (D) in both seizure and non-seizure rats after ischemia. The dashed line indicates the control value against which the other values are measured. CTL, control; NSZ, non-seizures; SZ, seizures.
    Mouse Monoclonal Anti Kchip2, supplied by NeuroMab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal anti kchip2/product/NeuroMab
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    mouse monoclonal anti kchip2 - by Bioz Stars, 2023-02
    86/100 stars

    Images

    1) Product Images from "Reduced expression of I A channels is associated with post-ischemic seizures"

    Article Title: Reduced expression of I A channels is associated with post-ischemic seizures

    Journal: Epilepsy research

    doi: 10.1016/j.eplepsyres.2016.05.008

    The expression of Kv4.3 and KChIP2 was unchanged after 25-min ischemia. (A & B) In contrast to Kv4.2, no obvious decrease of immunoreactivity for other somatodendritic IA channel subunits, Kv4.3 (A) and KChIP2 (B), was noticed in the brain of either non-seizure and seizure rats at 1 day after ischemia. (C & D) Western blotting showing that Kv4.3 and KChIP2 protein levels remained unchanged in the hippocampus (C) and cortex (D) in both seizure and non-seizure rats after ischemia. The dashed line indicates the control value against which the other values are measured. CTL, control; NSZ, non-seizures; SZ, seizures.
    Figure Legend Snippet: The expression of Kv4.3 and KChIP2 was unchanged after 25-min ischemia. (A & B) In contrast to Kv4.2, no obvious decrease of immunoreactivity for other somatodendritic IA channel subunits, Kv4.3 (A) and KChIP2 (B), was noticed in the brain of either non-seizure and seizure rats at 1 day after ischemia. (C & D) Western blotting showing that Kv4.3 and KChIP2 protein levels remained unchanged in the hippocampus (C) and cortex (D) in both seizure and non-seizure rats after ischemia. The dashed line indicates the control value against which the other values are measured. CTL, control; NSZ, non-seizures; SZ, seizures.

    Techniques Used: Expressing, Western Blot

    mouse monoclonal anti kchip2  (NeuroMab)

     
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    NeuroMab mouse monoclonal anti kchip2
    The expression of Kv4.3 and <t>KChIP2</t> was unchanged after 25-min ischemia. (A & B) In contrast to Kv4.2, no obvious decrease of immunoreactivity for other somatodendritic IA channel subunits, Kv4.3 (A) and KChIP2 (B), was noticed in the brain of either non-seizure and seizure rats at 1 day after ischemia. (C & D) Western blotting showing that Kv4.3 and <t>KChIP2</t> <t>protein</t> levels remained unchanged in the hippocampus (C) and cortex (D) in both seizure and non-seizure rats after ischemia. The dashed line indicates the control value against which the other values are measured. CTL, control; NSZ, non-seizures; SZ, seizures.
    Mouse Monoclonal Anti Kchip2, supplied by NeuroMab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal anti kchip2/product/NeuroMab
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    mouse monoclonal anti kchip2 - by Bioz Stars, 2023-02
    86/100 stars

    Images

    1) Product Images from "Reduced expression of I A channels is associated with post-ischemic seizures"

    Article Title: Reduced expression of I A channels is associated with post-ischemic seizures

    Journal: Epilepsy research

    doi: 10.1016/j.eplepsyres.2016.05.008

    The expression of Kv4.3 and KChIP2 was unchanged after 25-min ischemia. (A & B) In contrast to Kv4.2, no obvious decrease of immunoreactivity for other somatodendritic IA channel subunits, Kv4.3 (A) and KChIP2 (B), was noticed in the brain of either non-seizure and seizure rats at 1 day after ischemia. (C & D) Western blotting showing that Kv4.3 and KChIP2 protein levels remained unchanged in the hippocampus (C) and cortex (D) in both seizure and non-seizure rats after ischemia. The dashed line indicates the control value against which the other values are measured. CTL, control; NSZ, non-seizures; SZ, seizures.
    Figure Legend Snippet: The expression of Kv4.3 and KChIP2 was unchanged after 25-min ischemia. (A & B) In contrast to Kv4.2, no obvious decrease of immunoreactivity for other somatodendritic IA channel subunits, Kv4.3 (A) and KChIP2 (B), was noticed in the brain of either non-seizure and seizure rats at 1 day after ischemia. (C & D) Western blotting showing that Kv4.3 and KChIP2 protein levels remained unchanged in the hippocampus (C) and cortex (D) in both seizure and non-seizure rats after ischemia. The dashed line indicates the control value against which the other values are measured. CTL, control; NSZ, non-seizures; SZ, seizures.

    Techniques Used: Expressing, Western Blot

    mouse monoclonal anti kchip2  (NeuroMab)

     
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    NeuroMab mouse monoclonal anti kchip2
    Mouse Monoclonal Anti Kchip2, supplied by NeuroMab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal anti kchip2/product/NeuroMab
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    86/100 stars

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    mouse monoclonal anti kchip2 antibody  (NeuroMab)

     
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    NeuroMab mouse monoclonal anti kchip2 antibody
    Table 2
    Mouse Monoclonal Anti Kchip2 Antibody, supplied by NeuroMab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal anti kchip2 antibody/product/NeuroMab
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    mouse monoclonal anti kchip2 antibody - by Bioz Stars, 2023-02
    86/100 stars

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    1) Product Images from "Stabilization of Kv4 protein by the accessory K + channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K + currents"

    Article Title: Stabilization of Kv4 protein by the accessory K + channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K + currents

    Journal: The Journal of Physiology

    doi: 10.1113/jphysiol.2013.255836

    Table 2
    Figure Legend Snippet: Table 2

    Techniques Used:

    Table 3
    Figure Legend Snippet: Table 3

    Techniques Used:

    mouse monoclonal anti kchip2 antibody  (NeuroMab)

     
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    NeuroMab mouse monoclonal anti kchip2 antibody
    Table 2
    Mouse Monoclonal Anti Kchip2 Antibody, supplied by NeuroMab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal anti kchip2 antibody/product/NeuroMab
    Average 86 stars, based on 1 article reviews
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    1) Product Images from "Stabilization of Kv4 protein by the accessory K + channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K + currents"

    Article Title: Stabilization of Kv4 protein by the accessory K + channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K + currents

    Journal: The Journal of Physiology

    doi: 10.1113/jphysiol.2013.255836

    Table 2
    Figure Legend Snippet: Table 2

    Techniques Used:

    Table 3
    Figure Legend Snippet: Table 3

    Techniques Used:

    mouse monoclonal anti kchip2  (NeuroMab)

     
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    NeuroMab mouse monoclonal anti kchip2
    Mouse Monoclonal Anti Kchip2, supplied by NeuroMab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal anti kchip2/product/NeuroMab
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    mouse monoclonal anti kchip2 - by Bioz Stars, 2023-02
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    mouse monoclonal anti kchip2  (NeuroMab)

     
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    Structured Review

    NeuroMab mouse monoclonal anti kchip2
    Mouse Monoclonal Anti Kchip2, supplied by NeuroMab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal anti kchip2/product/NeuroMab
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
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    NeuroMab mouse monoclonal anti kchip2
    Mouse Monoclonal Anti Kchip2, supplied by NeuroMab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal anti kchip2/product/NeuroMab
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    mouse monoclonal anti kchip2 antibody  (NeuroMab)
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    NeuroMab mouse monoclonal anti kchip2 antibody
    Table 2
    Mouse Monoclonal Anti Kchip2 Antibody, supplied by NeuroMab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal anti kchip2 antibody/product/NeuroMab
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
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    Table 2

    Journal: The Journal of Physiology

    Article Title: Stabilization of Kv4 protein by the accessory K + channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K + currents

    doi: 10.1113/jphysiol.2013.255836

    Figure Lengend Snippet: Table 2

    Article Snippet: The mouse monoclonal anti-KChIP2 antibody was developed by and obtained from the UC Davis/NIH NeuroMab Facility, supported by NIH grant U24NS050606 and maintained by the University of California, Davis.

    Techniques: