mouse il 21  (Sino Biological)


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    • 90
    Name:
    IL21 cDNA ORF Clone in Cloning Vector Mouse
    Description:
    Full length Clone DNA of Mouse interleukin 21
    Catalog Number:
    MG50137-M
    Price:
    75.0
    Category:
    cDNA Clone
    Size:
    1Unit
    Product Aliases:
    IL-21 cDNA ORF Clone Mouse
    Molecule Name:
    IL21,IL-21,
    		Buy from Supplier

    Structured Review

    Sino Biological mouse il 21
    Serum <t>IL-21</t> and IL-33 are stimulated in B6 HDI mice but not BPS HDI mice. Sera from BPS, B6 and pUC18 HDI BALB/c mice were collected at indicated time points and levels of selected cytokines quantitated using multiplex-based assay. Group means and s.e.m. within group of serum IL-21 ( a ) and IL-33 ( b ) measurements are presented with group sizes ( n ) indicated. BPS and B6 mice data are compared against pUC18 mice and statistical significance calculated using unpaired two-tailed t -test. * p
    Full length Clone DNA of Mouse interleukin 21
    https://www.bioz.com/result/mouse il 21/product/Sino Biological
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    mouse il 21 - by Bioz Stars, 2021-04
    90/100 stars

    Images

    1) Product Images from "Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of viral clearance"

    Article Title: Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of viral clearance

    Journal: Nature Communications

    doi: 10.1038/s41467-017-02304-7

    Serum IL-21 and IL-33 are stimulated in B6 HDI mice but not BPS HDI mice. Sera from BPS, B6 and pUC18 HDI BALB/c mice were collected at indicated time points and levels of selected cytokines quantitated using multiplex-based assay. Group means and s.e.m. within group of serum IL-21 ( a ) and IL-33 ( b ) measurements are presented with group sizes ( n ) indicated. BPS and B6 mice data are compared against pUC18 mice and statistical significance calculated using unpaired two-tailed t -test. * p
    Figure Legend Snippet: Serum IL-21 and IL-33 are stimulated in B6 HDI mice but not BPS HDI mice. Sera from BPS, B6 and pUC18 HDI BALB/c mice were collected at indicated time points and levels of selected cytokines quantitated using multiplex-based assay. Group means and s.e.m. within group of serum IL-21 ( a ) and IL-33 ( b ) measurements are presented with group sizes ( n ) indicated. BPS and B6 mice data are compared against pUC18 mice and statistical significance calculated using unpaired two-tailed t -test. * p

    Techniques Used: Mouse Assay, Multiplex Assay, Two Tailed Test

    IL-21 or IL-33 treatments induce clearance of established BPS persistence. Plasmids expressing murine IL-21 or IL-33 and empty vector control were injected into BPS HDI mice at 4 and 7 weeks post injection (w.p.i.) (arrows). Sera were collected at indicated time points and levels of IL-21 and IL-33 ( a ), HBsAg ( b ), HBsAb ( c ) and HBeAg ( d ) were analysed using ELISA. Group means and s.e.m. within group are presented with group sizes ( n ) indicated. Group positivity percentage data are also presented for HBsAg ( b , right panel), HBsAb ( c , right panel) and HBeAg ( d , right panel). HBV DNA for each group were analysed using pooled serum in commercial quantitative assay ( e ). Dotted lines represent cut-off thresholds ( a , b – d , right panels) and lower limit of quantification ( e ) respectively. geq genome equivalents
    Figure Legend Snippet: IL-21 or IL-33 treatments induce clearance of established BPS persistence. Plasmids expressing murine IL-21 or IL-33 and empty vector control were injected into BPS HDI mice at 4 and 7 weeks post injection (w.p.i.) (arrows). Sera were collected at indicated time points and levels of IL-21 and IL-33 ( a ), HBsAg ( b ), HBsAb ( c ) and HBeAg ( d ) were analysed using ELISA. Group means and s.e.m. within group are presented with group sizes ( n ) indicated. Group positivity percentage data are also presented for HBsAg ( b , right panel), HBsAb ( c , right panel) and HBeAg ( d , right panel). HBV DNA for each group were analysed using pooled serum in commercial quantitative assay ( e ). Dotted lines represent cut-off thresholds ( a , b – d , right panels) and lower limit of quantification ( e ) respectively. geq genome equivalents

    Techniques Used: Expressing, Plasmid Preparation, Injection, Mouse Assay, Enzyme-linked Immunosorbent Assay

    IL-21-induced or IL-33-induced clearance of BPS persistence engenders protection from re-challenge. HDI mice harbouring BPS persistence were treated with injections of plasmids expressing IL-21 ( a ) or IL-33 ( b ) at 4 and 7 w.p.i. and those displaying at least 4 weeks of sustained HBsAg negativity (see Fig. 6 ) were re-challenged in the same way as initial BPS HDI. BPS HDI mice treated with vector control were used as control and re-challenged similarly ( c ). Sera were collected at indicated time points and levels of HBsAg (left), HBsAb (middle) and HBeAg (right) were analysed using ELISA. Dotted lines represent cut-off thresholds. w.p.i. weeks post injection of BPS re-challenge
    Figure Legend Snippet: IL-21-induced or IL-33-induced clearance of BPS persistence engenders protection from re-challenge. HDI mice harbouring BPS persistence were treated with injections of plasmids expressing IL-21 ( a ) or IL-33 ( b ) at 4 and 7 w.p.i. and those displaying at least 4 weeks of sustained HBsAg negativity (see Fig. 6 ) were re-challenged in the same way as initial BPS HDI. BPS HDI mice treated with vector control were used as control and re-challenged similarly ( c ). Sera were collected at indicated time points and levels of HBsAg (left), HBsAb (middle) and HBeAg (right) were analysed using ELISA. Dotted lines represent cut-off thresholds. w.p.i. weeks post injection of BPS re-challenge

    Techniques Used: Mouse Assay, Expressing, Plasmid Preparation, Enzyme-linked Immunosorbent Assay, Injection

    Related Articles

    Expressing:

    Article Title: Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of viral clearance
    Article Snippet: HBV HDI plasmid harbouring AAV sequences (pAAV/HBV) was a gift from Professor Pei-Jer Chen, National Taiwan University . .. Mouse IL-21 (MG50137-M-N) and IL-33 (MG50118-M-N) expression plasmids (Sino Biological, China) and rat monoclonal antibodies (anti-mIL-21: 16-9333; anti-mIL-33, 16-7211) (eBioscience, China) were purchased. .. Transfection and analysis of HBV markers and virions Culture and transfection of Huh-7 (TCHu182, Cell Bank of Chinese Academy of Sciences, China) and HepG2 (American Tissue Culture Collection, ATCC® Number: HB-8065™, Manassas, VA) cells were performed as previously described , .

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    • mouse il 21  (Sino Biological)
    90
    Sino Biological mouse il 21
    Serum <t>IL-21</t> and IL-33 are stimulated in B6 HDI mice but not BPS HDI mice. Sera from BPS, B6 and pUC18 HDI BALB/c mice were collected at indicated time points and levels of selected cytokines quantitated using multiplex-based assay. Group means and s.e.m. within group of serum IL-21 ( a ) and IL-33 ( b ) measurements are presented with group sizes ( n ) indicated. BPS and B6 mice data are compared against pUC18 mice and statistical significance calculated using unpaired two-tailed t -test. * p
    Mouse Il 21, supplied by Sino Biological, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse il 21/product/Sino Biological
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    mouse il 21 - by Bioz Stars, 2021-04
    90/100 stars
    		  Buy from Supplier
    IL21 Protein Mouse Recombinant  (Sino Biological)
    N/A
    A DNA sequence encoding the soluble form of mouse IL21 Q9ES17 Pro 25 Ser 146 was expressed with an initial Met at the C terminus
    		   Buy from Supplier
    IL21 Receptor Protein Mouse Recombinant  (Sino Biological)
    N/A
    A DNA sequence encoding the mouse Il21r AAL82636 1 Met1 Pro236 was expressed with the Fc region of human IgG1 at the C terminus
    		   Buy from Supplier

    Image Search Results


    Serum IL-21 and IL-33 are stimulated in B6 HDI mice but not BPS HDI mice. Sera from BPS, B6 and pUC18 HDI BALB/c mice were collected at indicated time points and levels of selected cytokines quantitated using multiplex-based assay. Group means and s.e.m. within group of serum IL-21 ( a ) and IL-33 ( b ) measurements are presented with group sizes ( n ) indicated. BPS and B6 mice data are compared against pUC18 mice and statistical significance calculated using unpaired two-tailed t -test. * p

    Journal: Nature Communications

    Article Title: Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of viral clearance

    doi: 10.1038/s41467-017-02304-7

    Figure Lengend Snippet: Serum IL-21 and IL-33 are stimulated in B6 HDI mice but not BPS HDI mice. Sera from BPS, B6 and pUC18 HDI BALB/c mice were collected at indicated time points and levels of selected cytokines quantitated using multiplex-based assay. Group means and s.e.m. within group of serum IL-21 ( a ) and IL-33 ( b ) measurements are presented with group sizes ( n ) indicated. BPS and B6 mice data are compared against pUC18 mice and statistical significance calculated using unpaired two-tailed t -test. * p

    Article Snippet: Mouse IL-21 (MG50137-M-N) and IL-33 (MG50118-M-N) expression plasmids (Sino Biological, China) and rat monoclonal antibodies (anti-mIL-21: 16-9333; anti-mIL-33, 16-7211) (eBioscience, China) were purchased.

    Techniques: Mouse Assay, Multiplex Assay, Two Tailed Test

    IL-21 or IL-33 treatments induce clearance of established BPS persistence. Plasmids expressing murine IL-21 or IL-33 and empty vector control were injected into BPS HDI mice at 4 and 7 weeks post injection (w.p.i.) (arrows). Sera were collected at indicated time points and levels of IL-21 and IL-33 ( a ), HBsAg ( b ), HBsAb ( c ) and HBeAg ( d ) were analysed using ELISA. Group means and s.e.m. within group are presented with group sizes ( n ) indicated. Group positivity percentage data are also presented for HBsAg ( b , right panel), HBsAb ( c , right panel) and HBeAg ( d , right panel). HBV DNA for each group were analysed using pooled serum in commercial quantitative assay ( e ). Dotted lines represent cut-off thresholds ( a , b – d , right panels) and lower limit of quantification ( e ) respectively. geq genome equivalents

    Journal: Nature Communications

    Article Title: Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of viral clearance

    doi: 10.1038/s41467-017-02304-7

    Figure Lengend Snippet: IL-21 or IL-33 treatments induce clearance of established BPS persistence. Plasmids expressing murine IL-21 or IL-33 and empty vector control were injected into BPS HDI mice at 4 and 7 weeks post injection (w.p.i.) (arrows). Sera were collected at indicated time points and levels of IL-21 and IL-33 ( a ), HBsAg ( b ), HBsAb ( c ) and HBeAg ( d ) were analysed using ELISA. Group means and s.e.m. within group are presented with group sizes ( n ) indicated. Group positivity percentage data are also presented for HBsAg ( b , right panel), HBsAb ( c , right panel) and HBeAg ( d , right panel). HBV DNA for each group were analysed using pooled serum in commercial quantitative assay ( e ). Dotted lines represent cut-off thresholds ( a , b – d , right panels) and lower limit of quantification ( e ) respectively. geq genome equivalents

    Article Snippet: Mouse IL-21 (MG50137-M-N) and IL-33 (MG50118-M-N) expression plasmids (Sino Biological, China) and rat monoclonal antibodies (anti-mIL-21: 16-9333; anti-mIL-33, 16-7211) (eBioscience, China) were purchased.

    Techniques: Expressing, Plasmid Preparation, Injection, Mouse Assay, Enzyme-linked Immunosorbent Assay

    IL-21-induced or IL-33-induced clearance of BPS persistence engenders protection from re-challenge. HDI mice harbouring BPS persistence were treated with injections of plasmids expressing IL-21 ( a ) or IL-33 ( b ) at 4 and 7 w.p.i. and those displaying at least 4 weeks of sustained HBsAg negativity (see Fig. 6 ) were re-challenged in the same way as initial BPS HDI. BPS HDI mice treated with vector control were used as control and re-challenged similarly ( c ). Sera were collected at indicated time points and levels of HBsAg (left), HBsAb (middle) and HBeAg (right) were analysed using ELISA. Dotted lines represent cut-off thresholds. w.p.i. weeks post injection of BPS re-challenge

    Journal: Nature Communications

    Article Title: Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of viral clearance

    doi: 10.1038/s41467-017-02304-7

    Figure Lengend Snippet: IL-21-induced or IL-33-induced clearance of BPS persistence engenders protection from re-challenge. HDI mice harbouring BPS persistence were treated with injections of plasmids expressing IL-21 ( a ) or IL-33 ( b ) at 4 and 7 w.p.i. and those displaying at least 4 weeks of sustained HBsAg negativity (see Fig. 6 ) were re-challenged in the same way as initial BPS HDI. BPS HDI mice treated with vector control were used as control and re-challenged similarly ( c ). Sera were collected at indicated time points and levels of HBsAg (left), HBsAb (middle) and HBeAg (right) were analysed using ELISA. Dotted lines represent cut-off thresholds. w.p.i. weeks post injection of BPS re-challenge

    Article Snippet: Mouse IL-21 (MG50137-M-N) and IL-33 (MG50118-M-N) expression plasmids (Sino Biological, China) and rat monoclonal antibodies (anti-mIL-21: 16-9333; anti-mIL-33, 16-7211) (eBioscience, China) were purchased.

    Techniques: Mouse Assay, Expressing, Plasmid Preparation, Enzyme-linked Immunosorbent Assay, Injection