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monoclonal mouse anti human antibodies against hnp1 3  (BMA Biomedicals)

 
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    BMA Biomedicals monoclonal mouse anti human antibodies against hnp1 3
    Immunohistochemistry of human neutrophil peptides 1-3 <t>(HNP1-3)</t> and human β-defensin 2 (HBD 2) in the synovial lining and sublining area of an RA patient (similar in OA patients) . Antibodies to HNP1-3 stained positive in the lining and adjacent sublining area, whereas HBD-2 was found only in deep sublining zones. Magnification 400×.
    Monoclonal Mouse Anti Human Antibodies Against Hnp1 3, supplied by BMA Biomedicals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/monoclonal mouse anti human antibodies against hnp1 3/product/BMA Biomedicals
    Average 86 stars, based on 1 article reviews
    monoclonal mouse anti human antibodies against hnp1 3 - by Bioz Stars, 2025-04
    86/100 stars

    Images

    1) Product Images from "Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis"

    Article Title: Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis

    Journal: Arthritis Research & Therapy

    doi: 10.1186/ar3044

    Immunohistochemistry of human neutrophil peptides 1-3 (HNP1-3) and human β-defensin 2 (HBD 2) in the synovial lining and sublining area of an RA patient (similar in OA patients) . Antibodies to HNP1-3 stained positive in the lining and adjacent sublining area, whereas HBD-2 was found only in deep sublining zones. Magnification 400×.
    Figure Legend Snippet: Immunohistochemistry of human neutrophil peptides 1-3 (HNP1-3) and human β-defensin 2 (HBD 2) in the synovial lining and sublining area of an RA patient (similar in OA patients) . Antibodies to HNP1-3 stained positive in the lining and adjacent sublining area, whereas HBD-2 was found only in deep sublining zones. Magnification 400×.

    Techniques Used: Immunohistochemistry, Staining

    Double immunofluorescence of human neutrophil peptides 1-3 (HNP1-3) and human β-defensin 2 (HBD 2) in synovial tissue of an RA patient . Arrowheads show double-positive cells. Left panels: HNP1-3 (red staining) were co-localized with neutrophil elastase (green staining), as indicated by the yellow color in this overlay image. Right panels : HBD-2 (red fluorescence) was rarely detected. Some fibroblasts (green fluorescence in the upper right panel) and some CD19 + B lymphocytes (green fluorescence in the lower right panel) stained positive for HBD-2 (yellow overlay). Magnification 400×.
    Figure Legend Snippet: Double immunofluorescence of human neutrophil peptides 1-3 (HNP1-3) and human β-defensin 2 (HBD 2) in synovial tissue of an RA patient . Arrowheads show double-positive cells. Left panels: HNP1-3 (red staining) were co-localized with neutrophil elastase (green staining), as indicated by the yellow color in this overlay image. Right panels : HBD-2 (red fluorescence) was rarely detected. Some fibroblasts (green fluorescence in the upper right panel) and some CD19 + B lymphocytes (green fluorescence in the lower right panel) stained positive for HBD-2 (yellow overlay). Magnification 400×.

    Techniques Used: Immunofluorescence, Staining, Fluorescence

    Secretion of defensins from synovial tissue/cells and density of synovial neutrophils . (a) Levels of human neutrophil peptides 1-3 (HNP1-3) in superfusate of synovial tissue of two patients with rheumatoid arthritis (RA) and osteoarthritis (OA) (four replicates per patient). The dotted line indicates the detection limit. (b) Levels of human β-defensin-2 (HBD 2) in supernatant of synovial tissue of two patients with RA and OA (four replicates per patient). The dotted line indicates the detection limit. (c) Levels of defensins in supernatant of cultured mixed synovial cells over time. Compare the levels with the detection levels in panels (a) and (b). After 20 hours, HNP1-3 were in the detectable range, which was not the case for HBD-2. The data of four OA patients are given (two replicates of every patient), which was similar in RA patients (data not shown). (d) Density of synovial neutrophils in RA and OA synovial tissue. Every symbol represents the average density of neutrophils of one patient, as measured in 17 high-power fields (400×) of two to three synovial tissue sections, including deep sublining areas.
    Figure Legend Snippet: Secretion of defensins from synovial tissue/cells and density of synovial neutrophils . (a) Levels of human neutrophil peptides 1-3 (HNP1-3) in superfusate of synovial tissue of two patients with rheumatoid arthritis (RA) and osteoarthritis (OA) (four replicates per patient). The dotted line indicates the detection limit. (b) Levels of human β-defensin-2 (HBD 2) in supernatant of synovial tissue of two patients with RA and OA (four replicates per patient). The dotted line indicates the detection limit. (c) Levels of defensins in supernatant of cultured mixed synovial cells over time. Compare the levels with the detection levels in panels (a) and (b). After 20 hours, HNP1-3 were in the detectable range, which was not the case for HBD-2. The data of four OA patients are given (two replicates of every patient), which was similar in RA patients (data not shown). (d) Density of synovial neutrophils in RA and OA synovial tissue. Every symbol represents the average density of neutrophils of one patient, as measured in 17 high-power fields (400×) of two to three synovial tissue sections, including deep sublining areas.

    Techniques Used: Cell Culture

    Influence of tumor necrosis factor (TNF) on levels of human neutrophil peptides 1-3 (HNP1-3) of mixed synoviocytes . The data are derived from five OA and five RA patients (two replicates of every patient). Control HNP1-3 levels were 58.3 ± 7.0 pg/ml in OA patients and 147.2 ± 37.5 pg/ml in RA patients.
    Figure Legend Snippet: Influence of tumor necrosis factor (TNF) on levels of human neutrophil peptides 1-3 (HNP1-3) of mixed synoviocytes . The data are derived from five OA and five RA patients (two replicates of every patient). Control HNP1-3 levels were 58.3 ± 7.0 pg/ml in OA patients and 147.2 ± 37.5 pg/ml in RA patients.

    Techniques Used: Derivative Assay

    Influence of norepinephrine (NE) and cortisol (Cort) on human neutrophil peptides 1-3 (HNP1-3) levels in patients with rheumatoid arthritis (RA) and osteoarthritis (OA) . (a, b) Influence of norepinephrine on HNP1-3 levels in supernatants of mixed synoviocytes. The data are derived from five OA and five RA patients (two replicates of every patient). Control HNP1-3 values were as described in the legend of Figure 4. (c, d) Influence of cortisol or norepinephrine plus cortisol on HNP1-3 levels in supernatants of mixed synoviocytes. The data are derived from nine OA and seven RA patients (three replicates of every patient). Control HNP1-3 levels were 160.2 ± 50.3 pg/ml in OA patients and 73.5 ± 19.9 pg/ml in RA patients.
    Figure Legend Snippet: Influence of norepinephrine (NE) and cortisol (Cort) on human neutrophil peptides 1-3 (HNP1-3) levels in patients with rheumatoid arthritis (RA) and osteoarthritis (OA) . (a, b) Influence of norepinephrine on HNP1-3 levels in supernatants of mixed synoviocytes. The data are derived from five OA and five RA patients (two replicates of every patient). Control HNP1-3 values were as described in the legend of Figure 4. (c, d) Influence of cortisol or norepinephrine plus cortisol on HNP1-3 levels in supernatants of mixed synoviocytes. The data are derived from nine OA and seven RA patients (three replicates of every patient). Control HNP1-3 levels were 160.2 ± 50.3 pg/ml in OA patients and 73.5 ± 19.9 pg/ml in RA patients.

    Techniques Used: Derivative Assay



    Similar Products

    monoclonal mouse anti human antibodies against hnp1 3  (BMA Biomedicals)
    86
    BMA Biomedicals monoclonal mouse anti human antibodies against hnp1 3
    Immunohistochemistry of human neutrophil peptides 1-3 <t>(HNP1-3)</t> and human β-defensin 2 (HBD 2) in the synovial lining and sublining area of an RA patient (similar in OA patients) . Antibodies to HNP1-3 stained positive in the lining and adjacent sublining area, whereas HBD-2 was found only in deep sublining zones. Magnification 400×.
    Monoclonal Mouse Anti Human Antibodies Against Hnp1 3, supplied by BMA Biomedicals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/monoclonal mouse anti human antibodies against hnp1 3/product/BMA Biomedicals
    Average 86 stars, based on 1 article reviews
    monoclonal mouse anti human antibodies against hnp1 3 - by Bioz Stars, 2025-04
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    Immunohistochemistry of human neutrophil peptides 1-3 (HNP1-3) and human β-defensin 2 (HBD 2) in the synovial lining and sublining area of an RA patient (similar in OA patients) . Antibodies to HNP1-3 stained positive in the lining and adjacent sublining area, whereas HBD-2 was found only in deep sublining zones. Magnification 400×.

    Journal: Arthritis Research & Therapy

    Article Title: Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis

    doi: 10.1186/ar3044

    Figure Lengend Snippet: Immunohistochemistry of human neutrophil peptides 1-3 (HNP1-3) and human β-defensin 2 (HBD 2) in the synovial lining and sublining area of an RA patient (similar in OA patients) . Antibodies to HNP1-3 stained positive in the lining and adjacent sublining area, whereas HBD-2 was found only in deep sublining zones. Magnification 400×.

    Article Snippet: Then, sections were incubated with either monoclonal mouse anti-human antibodies against HNP1-3 (BMA Biomedicals, Augst, Switzerland, no. T 1034; dilution, 1:1,000; these antibodies recognize HNP-1 to -3) or polyclonal rabbit anti-human antibodies against HBD-2 (Biologo, Kronshagen, Germany, no. DEF002; dilution, 1:100).

    Techniques: Immunohistochemistry, Staining

    Double immunofluorescence of human neutrophil peptides 1-3 (HNP1-3) and human β-defensin 2 (HBD 2) in synovial tissue of an RA patient . Arrowheads show double-positive cells. Left panels: HNP1-3 (red staining) were co-localized with neutrophil elastase (green staining), as indicated by the yellow color in this overlay image. Right panels : HBD-2 (red fluorescence) was rarely detected. Some fibroblasts (green fluorescence in the upper right panel) and some CD19 + B lymphocytes (green fluorescence in the lower right panel) stained positive for HBD-2 (yellow overlay). Magnification 400×.

    Journal: Arthritis Research & Therapy

    Article Title: Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis

    doi: 10.1186/ar3044

    Figure Lengend Snippet: Double immunofluorescence of human neutrophil peptides 1-3 (HNP1-3) and human β-defensin 2 (HBD 2) in synovial tissue of an RA patient . Arrowheads show double-positive cells. Left panels: HNP1-3 (red staining) were co-localized with neutrophil elastase (green staining), as indicated by the yellow color in this overlay image. Right panels : HBD-2 (red fluorescence) was rarely detected. Some fibroblasts (green fluorescence in the upper right panel) and some CD19 + B lymphocytes (green fluorescence in the lower right panel) stained positive for HBD-2 (yellow overlay). Magnification 400×.

    Article Snippet: Then, sections were incubated with either monoclonal mouse anti-human antibodies against HNP1-3 (BMA Biomedicals, Augst, Switzerland, no. T 1034; dilution, 1:1,000; these antibodies recognize HNP-1 to -3) or polyclonal rabbit anti-human antibodies against HBD-2 (Biologo, Kronshagen, Germany, no. DEF002; dilution, 1:100).

    Techniques: Immunofluorescence, Staining, Fluorescence

    Secretion of defensins from synovial tissue/cells and density of synovial neutrophils . (a) Levels of human neutrophil peptides 1-3 (HNP1-3) in superfusate of synovial tissue of two patients with rheumatoid arthritis (RA) and osteoarthritis (OA) (four replicates per patient). The dotted line indicates the detection limit. (b) Levels of human β-defensin-2 (HBD 2) in supernatant of synovial tissue of two patients with RA and OA (four replicates per patient). The dotted line indicates the detection limit. (c) Levels of defensins in supernatant of cultured mixed synovial cells over time. Compare the levels with the detection levels in panels (a) and (b). After 20 hours, HNP1-3 were in the detectable range, which was not the case for HBD-2. The data of four OA patients are given (two replicates of every patient), which was similar in RA patients (data not shown). (d) Density of synovial neutrophils in RA and OA synovial tissue. Every symbol represents the average density of neutrophils of one patient, as measured in 17 high-power fields (400×) of two to three synovial tissue sections, including deep sublining areas.

    Journal: Arthritis Research & Therapy

    Article Title: Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis

    doi: 10.1186/ar3044

    Figure Lengend Snippet: Secretion of defensins from synovial tissue/cells and density of synovial neutrophils . (a) Levels of human neutrophil peptides 1-3 (HNP1-3) in superfusate of synovial tissue of two patients with rheumatoid arthritis (RA) and osteoarthritis (OA) (four replicates per patient). The dotted line indicates the detection limit. (b) Levels of human β-defensin-2 (HBD 2) in supernatant of synovial tissue of two patients with RA and OA (four replicates per patient). The dotted line indicates the detection limit. (c) Levels of defensins in supernatant of cultured mixed synovial cells over time. Compare the levels with the detection levels in panels (a) and (b). After 20 hours, HNP1-3 were in the detectable range, which was not the case for HBD-2. The data of four OA patients are given (two replicates of every patient), which was similar in RA patients (data not shown). (d) Density of synovial neutrophils in RA and OA synovial tissue. Every symbol represents the average density of neutrophils of one patient, as measured in 17 high-power fields (400×) of two to three synovial tissue sections, including deep sublining areas.

    Article Snippet: Then, sections were incubated with either monoclonal mouse anti-human antibodies against HNP1-3 (BMA Biomedicals, Augst, Switzerland, no. T 1034; dilution, 1:1,000; these antibodies recognize HNP-1 to -3) or polyclonal rabbit anti-human antibodies against HBD-2 (Biologo, Kronshagen, Germany, no. DEF002; dilution, 1:100).

    Techniques: Cell Culture

    Influence of tumor necrosis factor (TNF) on levels of human neutrophil peptides 1-3 (HNP1-3) of mixed synoviocytes . The data are derived from five OA and five RA patients (two replicates of every patient). Control HNP1-3 levels were 58.3 ± 7.0 pg/ml in OA patients and 147.2 ± 37.5 pg/ml in RA patients.

    Journal: Arthritis Research & Therapy

    Article Title: Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis

    doi: 10.1186/ar3044

    Figure Lengend Snippet: Influence of tumor necrosis factor (TNF) on levels of human neutrophil peptides 1-3 (HNP1-3) of mixed synoviocytes . The data are derived from five OA and five RA patients (two replicates of every patient). Control HNP1-3 levels were 58.3 ± 7.0 pg/ml in OA patients and 147.2 ± 37.5 pg/ml in RA patients.

    Article Snippet: Then, sections were incubated with either monoclonal mouse anti-human antibodies against HNP1-3 (BMA Biomedicals, Augst, Switzerland, no. T 1034; dilution, 1:1,000; these antibodies recognize HNP-1 to -3) or polyclonal rabbit anti-human antibodies against HBD-2 (Biologo, Kronshagen, Germany, no. DEF002; dilution, 1:100).

    Techniques: Derivative Assay

    Influence of norepinephrine (NE) and cortisol (Cort) on human neutrophil peptides 1-3 (HNP1-3) levels in patients with rheumatoid arthritis (RA) and osteoarthritis (OA) . (a, b) Influence of norepinephrine on HNP1-3 levels in supernatants of mixed synoviocytes. The data are derived from five OA and five RA patients (two replicates of every patient). Control HNP1-3 values were as described in the legend of Figure 4. (c, d) Influence of cortisol or norepinephrine plus cortisol on HNP1-3 levels in supernatants of mixed synoviocytes. The data are derived from nine OA and seven RA patients (three replicates of every patient). Control HNP1-3 levels were 160.2 ± 50.3 pg/ml in OA patients and 73.5 ± 19.9 pg/ml in RA patients.

    Journal: Arthritis Research & Therapy

    Article Title: Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis

    doi: 10.1186/ar3044

    Figure Lengend Snippet: Influence of norepinephrine (NE) and cortisol (Cort) on human neutrophil peptides 1-3 (HNP1-3) levels in patients with rheumatoid arthritis (RA) and osteoarthritis (OA) . (a, b) Influence of norepinephrine on HNP1-3 levels in supernatants of mixed synoviocytes. The data are derived from five OA and five RA patients (two replicates of every patient). Control HNP1-3 values were as described in the legend of Figure 4. (c, d) Influence of cortisol or norepinephrine plus cortisol on HNP1-3 levels in supernatants of mixed synoviocytes. The data are derived from nine OA and seven RA patients (three replicates of every patient). Control HNP1-3 levels were 160.2 ± 50.3 pg/ml in OA patients and 73.5 ± 19.9 pg/ml in RA patients.

    Article Snippet: Then, sections were incubated with either monoclonal mouse anti-human antibodies against HNP1-3 (BMA Biomedicals, Augst, Switzerland, no. T 1034; dilution, 1:1,000; these antibodies recognize HNP-1 to -3) or polyclonal rabbit anti-human antibodies against HBD-2 (Biologo, Kronshagen, Germany, no. DEF002; dilution, 1:100).

    Techniques: Derivative Assay