monoclonal glutaryl lysine antibodies  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc monoclonal glutaryl lysine antibodies
    Protein acylation by four- and five-carbon dicarboxylic acyl-CoAs. The terminal carboxylic acids <t>in</t> <t>succinyl-CoA,</t> <t>glutaryl-CoA,</t> HMG-CoA, and 3-methylglutaryl-CoA facilitate non-enzymatic lysine acylation through intramolecular general base catalysis-mediated formation of a highly reactive cyclic anhydride intermediate. In a mouse model of the human disorder HMG-CoA lyase deficiency, HMG-CoA and 3-methylglutaryl-CoA accumulate and, consequently, protein lysine HMGylation and 3-MGylation are elevated. In a mouse model of the human disorder glutaric academia (GA I), glutaryl-CoA accumulates and, consequently, protein lysine glutarylation is elevated.
    Monoclonal Glutaryl Lysine Antibodies, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/monoclonal glutaryl lysine antibodies/product/Cell Signaling Technology Inc
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    monoclonal glutaryl lysine antibodies - by Bioz Stars, 2023-05
    93/100 stars

    Images

    1) Product Images from "A Class of Reactive Acyl-CoA Species Reveals the Non-Enzymatic Origins of Protein Acylation"

    Article Title: A Class of Reactive Acyl-CoA Species Reveals the Non-Enzymatic Origins of Protein Acylation

    Journal: Cell metabolism

    doi: 10.1016/j.cmet.2017.03.006

    Protein acylation by four- and five-carbon dicarboxylic acyl-CoAs. The terminal carboxylic acids in succinyl-CoA, glutaryl-CoA, HMG-CoA, and 3-methylglutaryl-CoA facilitate non-enzymatic lysine acylation through intramolecular general base catalysis-mediated formation of a highly reactive cyclic anhydride intermediate. In a mouse model of the human disorder HMG-CoA lyase deficiency, HMG-CoA and 3-methylglutaryl-CoA accumulate and, consequently, protein lysine HMGylation and 3-MGylation are elevated. In a mouse model of the human disorder glutaric academia (GA I), glutaryl-CoA accumulates and, consequently, protein lysine glutarylation is elevated.
    Figure Legend Snippet: Protein acylation by four- and five-carbon dicarboxylic acyl-CoAs. The terminal carboxylic acids in succinyl-CoA, glutaryl-CoA, HMG-CoA, and 3-methylglutaryl-CoA facilitate non-enzymatic lysine acylation through intramolecular general base catalysis-mediated formation of a highly reactive cyclic anhydride intermediate. In a mouse model of the human disorder HMG-CoA lyase deficiency, HMG-CoA and 3-methylglutaryl-CoA accumulate and, consequently, protein lysine HMGylation and 3-MGylation are elevated. In a mouse model of the human disorder glutaric academia (GA I), glutaryl-CoA accumulates and, consequently, protein lysine glutarylation is elevated.

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    monoclonal glutaryl lysine antibodies  (Cell Signaling Technology Inc)


    Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
    Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
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  • About
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    • 93
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    Structured Review

    Cell Signaling Technology Inc monoclonal glutaryl lysine antibodies
    Protein acylation by four- and five-carbon dicarboxylic acyl-CoAs. The terminal carboxylic acids <t>in</t> <t>succinyl-CoA,</t> <t>glutaryl-CoA,</t> HMG-CoA, and 3-methylglutaryl-CoA facilitate non-enzymatic lysine acylation through intramolecular general base catalysis-mediated formation of a highly reactive cyclic anhydride intermediate. In a mouse model of the human disorder HMG-CoA lyase deficiency, HMG-CoA and 3-methylglutaryl-CoA accumulate and, consequently, protein lysine HMGylation and 3-MGylation are elevated. In a mouse model of the human disorder glutaric academia (GA I), glutaryl-CoA accumulates and, consequently, protein lysine glutarylation is elevated.
    Monoclonal Glutaryl Lysine Antibodies, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/monoclonal glutaryl lysine antibodies/product/Cell Signaling Technology Inc
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    monoclonal glutaryl lysine antibodies - by Bioz Stars, 2023-05
    93/100 stars

    Images

    1) Product Images from "A Class of Reactive Acyl-CoA Species Reveals the Non-Enzymatic Origins of Protein Acylation"

    Article Title: A Class of Reactive Acyl-CoA Species Reveals the Non-Enzymatic Origins of Protein Acylation

    Journal: Cell metabolism

    doi: 10.1016/j.cmet.2017.03.006

    Protein acylation by four- and five-carbon dicarboxylic acyl-CoAs. The terminal carboxylic acids in succinyl-CoA, glutaryl-CoA, HMG-CoA, and 3-methylglutaryl-CoA facilitate non-enzymatic lysine acylation through intramolecular general base catalysis-mediated formation of a highly reactive cyclic anhydride intermediate. In a mouse model of the human disorder HMG-CoA lyase deficiency, HMG-CoA and 3-methylglutaryl-CoA accumulate and, consequently, protein lysine HMGylation and 3-MGylation are elevated. In a mouse model of the human disorder glutaric academia (GA I), glutaryl-CoA accumulates and, consequently, protein lysine glutarylation is elevated.
    Figure Legend Snippet: Protein acylation by four- and five-carbon dicarboxylic acyl-CoAs. The terminal carboxylic acids in succinyl-CoA, glutaryl-CoA, HMG-CoA, and 3-methylglutaryl-CoA facilitate non-enzymatic lysine acylation through intramolecular general base catalysis-mediated formation of a highly reactive cyclic anhydride intermediate. In a mouse model of the human disorder HMG-CoA lyase deficiency, HMG-CoA and 3-methylglutaryl-CoA accumulate and, consequently, protein lysine HMGylation and 3-MGylation are elevated. In a mouse model of the human disorder glutaric academia (GA I), glutaryl-CoA accumulates and, consequently, protein lysine glutarylation is elevated.

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    • monoclonal glutaryl lysine antibodies  (Cell Signaling Technology Inc)
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    Cell Signaling Technology Inc monoclonal glutaryl lysine antibodies
    Protein acylation by four- and five-carbon dicarboxylic acyl-CoAs. The terminal carboxylic acids <t>in</t> <t>succinyl-CoA,</t> <t>glutaryl-CoA,</t> HMG-CoA, and 3-methylglutaryl-CoA facilitate non-enzymatic lysine acylation through intramolecular general base catalysis-mediated formation of a highly reactive cyclic anhydride intermediate. In a mouse model of the human disorder HMG-CoA lyase deficiency, HMG-CoA and 3-methylglutaryl-CoA accumulate and, consequently, protein lysine HMGylation and 3-MGylation are elevated. In a mouse model of the human disorder glutaric academia (GA I), glutaryl-CoA accumulates and, consequently, protein lysine glutarylation is elevated.
    Monoclonal Glutaryl Lysine Antibodies, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/monoclonal glutaryl lysine antibodies/product/Cell Signaling Technology Inc
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    monoclonal glutaryl lysine antibodies - by Bioz Stars, 2023-05
    93/100 stars
    		  Buy from Supplier

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    Protein acylation by four- and five-carbon dicarboxylic acyl-CoAs. The terminal carboxylic acids in succinyl-CoA, glutaryl-CoA, HMG-CoA, and 3-methylglutaryl-CoA facilitate non-enzymatic lysine acylation through intramolecular general base catalysis-mediated formation of a highly reactive cyclic anhydride intermediate. In a mouse model of the human disorder HMG-CoA lyase deficiency, HMG-CoA and 3-methylglutaryl-CoA accumulate and, consequently, protein lysine HMGylation and 3-MGylation are elevated. In a mouse model of the human disorder glutaric academia (GA I), glutaryl-CoA accumulates and, consequently, protein lysine glutarylation is elevated.

    Journal: Cell metabolism

    Article Title: A Class of Reactive Acyl-CoA Species Reveals the Non-Enzymatic Origins of Protein Acylation

    doi: 10.1016/j.cmet.2017.03.006

    Figure Lengend Snippet: Protein acylation by four- and five-carbon dicarboxylic acyl-CoAs. The terminal carboxylic acids in succinyl-CoA, glutaryl-CoA, HMG-CoA, and 3-methylglutaryl-CoA facilitate non-enzymatic lysine acylation through intramolecular general base catalysis-mediated formation of a highly reactive cyclic anhydride intermediate. In a mouse model of the human disorder HMG-CoA lyase deficiency, HMG-CoA and 3-methylglutaryl-CoA accumulate and, consequently, protein lysine HMGylation and 3-MGylation are elevated. In a mouse model of the human disorder glutaric academia (GA I), glutaryl-CoA accumulates and, consequently, protein lysine glutarylation is elevated.

    Article Snippet: Antibodies used were a polyclonal acetyl-lysine and monoclonal glutaryl-lysine antibodies (Cell Signaling, non-commercial), polyclonal succinyl-lysine, butyryl-lysine, and malonyl-lysine antibodies (PTM Biolabs, Inc.), and custom-made polyclonal glutaryl-lysine, succinyl-lysine, hydroxylmethylglutaryl-lysine (custom made from Yenzym Antibodies) and anti-myc (Santa Cruz Biotechnology).

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