ml297 (Alomone Labs)


Structured Review

Ml297, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ml297/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Encephalopathy-causing mutations in Gβ 1 ( GNB1 ) alter regulation of neuronal GIRK channels"
Article Title: Encephalopathy-causing mutations in Gβ 1 ( GNB1 ) alter regulation of neuronal GIRK channels
Journal: iScience
doi: 10.1016/j.isci.2021.103018

Figure Legend Snippet: Rescue of GIRK channel activity by VU0529331 and ML297 in the presence of LoF mutants I80N and I80T Oocytes expressed GIRK2 (2 ng RNA) or GIRK1/3 (3 ng) channels, with or without Gβ WT (5 ng), I80N and I80T (10 ng), and Gγ (1/5 of Gβ). (A) Representative records of GIRK2 currents and their activation by 40 μM of VU0529331 in oocytes expressing Gβγ. (B and C) Summary of GIRK2 currents with and without Gβγ before (B) and after (C) the application of 40 μM VU0529331. (D) Fold activation of GIRK2 by 40 μM of VU0529331. (E) GIRK1/3 currents and their activation by 10 μM of ML297 in the presence of Gβγ. (F and G) Summary of GIRK1/3 currents with and without Gβγ before (F) and after (G) the application of 10 μM ML297. (H) Fold activation of GIRK1/3 by 10 μM of ML297 (N = 1).
Techniques Used: Activity Assay, Activation Assay, Expressing

Figure Legend Snippet:
Techniques Used: Recombinant, Modification, Mutagenesis, Software
ml297 (Alomone Labs)


Structured Review

Ml297, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ml297/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Encephalopathy-causing mutations in Gβ 1 ( GNB1 ) alter regulation of neuronal GIRK channels"
Article Title: Encephalopathy-causing mutations in Gβ 1 ( GNB1 ) alter regulation of neuronal GIRK channels
Journal: iScience
doi: 10.1016/j.isci.2021.103018

Figure Legend Snippet: Rescue of GIRK channel activity by VU0529331 and ML297 in the presence of LoF mutants I80N and I80T Oocytes expressed GIRK2 (2 ng RNA) or GIRK1/3 (3 ng) channels, with or without Gβ WT (5 ng), I80N and I80T (10 ng), and Gγ (1/5 of Gβ). (A) Representative records of GIRK2 currents and their activation by 40 μM of VU0529331 in oocytes expressing Gβγ. (B and C) Summary of GIRK2 currents with and without Gβγ before (B) and after (C) the application of 40 μM VU0529331. (D) Fold activation of GIRK2 by 40 μM of VU0529331. (E) GIRK1/3 currents and their activation by 10 μM of ML297 in the presence of Gβγ. (F and G) Summary of GIRK1/3 currents with and without Gβγ before (F) and after (G) the application of 10 μM ML297. (H) Fold activation of GIRK1/3 by 10 μM of ML297 (N = 1).
Techniques Used: Activity Assay, Activation Assay, Expressing

Figure Legend Snippet:
Techniques Used: Recombinant, Modification, Mutagenesis, Software
ml297 (Alomone Labs)


Structured Review

Ml297, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ml297/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Encephalopathy-causing mutations in Gβ 1 ( GNB1 ) alter regulation of neuronal GIRK channels"
Article Title: Encephalopathy-causing mutations in Gβ 1 ( GNB1 ) alter regulation of neuronal GIRK channels
Journal: iScience
doi: 10.1016/j.isci.2021.103018

Figure Legend Snippet: Rescue of GIRK channel activity by VU0529331 and ML297 in the presence of LoF mutants I80N and I80T Oocytes expressed GIRK2 (2 ng RNA) or GIRK1/3 (3 ng) channels, with or without Gβ WT (5 ng), I80N and I80T (10 ng), and Gγ (1/5 of Gβ). (A) Representative records of GIRK2 currents and their activation by 40 μM of VU0529331 in oocytes expressing Gβγ. (B and C) Summary of GIRK2 currents with and without Gβγ before (B) and after (C) the application of 40 μM VU0529331. (D) Fold activation of GIRK2 by 40 μM of VU0529331. (E) GIRK1/3 currents and their activation by 10 μM of ML297 in the presence of Gβγ. (F and G) Summary of GIRK1/3 currents with and without Gβγ before (F) and after (G) the application of 10 μM ML297. (H) Fold activation of GIRK1/3 by 10 μM of ML297 (N = 1).
Techniques Used: Activity Assay, Activation Assay, Expressing

Figure Legend Snippet:
Techniques Used: Recombinant, Modification, Mutagenesis, Software