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microarray data  (Biotechnology Information)

 
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    Biotechnology Information microarray data
    Microarray Data, supplied by Biotechnology Information, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/microarray data/product/Biotechnology Information
    Average 90 stars, based on 1 article reviews
    microarray data - by Bioz Stars, 2026-04
    90/100 stars

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    Image Search Results


    Baf60c regulates Musclin transcription through modification of chromatin accessibility. (a) Chromatin accessibility analysis in quadriceps muscles from 3-month-old BcMKO and Bc flox/flox mice based on ATAC-seq data. (b) Venn diagram of DEGs from microarray data of BcMKO and Bc flox/flox mice mentioned in (cutoff: P < 0.05 and log 2 (FC) > 0.5) and differential peak-annotated genes in ATAC-seq data indicated in (cutoff: P adjust < 0.05 and log 2 (FC) > 0.5). (c) Heatmap depicting the differential peaks in ATAC-seq analysis associated with secreted proteins mentioned in . (d) Genome browser tracks of ATAC-seq of BcMKO and Bc flox/flox mice and the indicated ChIP-seq data in the Musclin gene locus. H3K4me3 and H3K27ac are well-known histone hallmarks for transcription initiation and active enhancers, respectively, and H3K4me2 is reported to modulate the stability of RNA polymerase Ⅱ pausing.

    Journal: Life Metabolism

    Article Title: Baf60c in skeletal muscle regulates adipose tissue thermogenesis via Musclin-mediated endocrine signaling

    doi: 10.1093/lifemeta/loaf015

    Figure Lengend Snippet: Baf60c regulates Musclin transcription through modification of chromatin accessibility. (a) Chromatin accessibility analysis in quadriceps muscles from 3-month-old BcMKO and Bc flox/flox mice based on ATAC-seq data. (b) Venn diagram of DEGs from microarray data of BcMKO and Bc flox/flox mice mentioned in (cutoff: P < 0.05 and log 2 (FC) > 0.5) and differential peak-annotated genes in ATAC-seq data indicated in (cutoff: P adjust < 0.05 and log 2 (FC) > 0.5). (c) Heatmap depicting the differential peaks in ATAC-seq analysis associated with secreted proteins mentioned in . (d) Genome browser tracks of ATAC-seq of BcMKO and Bc flox/flox mice and the indicated ChIP-seq data in the Musclin gene locus. H3K4me3 and H3K27ac are well-known histone hallmarks for transcription initiation and active enhancers, respectively, and H3K4me2 is reported to modulate the stability of RNA polymerase Ⅱ pausing.

    Article Snippet: The heatmap of representative secreted protein-encoding gene expression indicated in was analyzed using the microarray data of skeletal muscles from BcMKO and control mice, which had been deposited in Mendeley data ( https://doi.org/10.17632/28ks32hwxh.1 ).

    Techniques: Modification, Muscles, Microarray, ChIP-sequencing